Impact of Non-Pharmacological Interventions on the Mechanisms of Atherosclerosis

Abstract

Atherosclerosis remains the leading cause of mortality and morbidity worldwide characterized by the deposition of lipids and fibrous elements in the form of atheroma plaques in vascular areas which are hemodynamically overloaded. The global burden of atherosclerotic cardiovascular disease is steadily increasing and is considered the largest known non-infectious pandemic. The management of atherosclerotic cardiovascular disease is increasing the cost of health care worldwide, which is a concern for researchers and physicians and has caused them to strive to find effective long-term strategies to improve the efficiency of treatments by managing conventional risk factors. Primary prevention of atherosclerotic cardiovascular disease is the preferred method to reduce cardiovascular risk. Fasting, a Mediterranean diet, and caloric restriction can be considered useful clinical tools. The protective impact of physical exercise over the cardiovascular system has been studied in recent years with the intention of explaining the mechanisms involved; the increase in heat shock proteins, antioxidant enzymes and regulators of cardiac myocyte proliferation concentration seem to be the molecular and biochemical shifts that are involved. Developing new therapeutic strategies such as vagus nerve stimulation, either to prevent or slow the disease’s onset and progression, will surely have a profound effect on the lives of millions of people.

Physical Activity of the Elderly with Cardiovascular Disease During the COVID -19 Pandemic

“…Lifestyle modification was recommended as the first line to reduce the risk of cardiovascular disease in addition to pharmacological treatment (1) . Non-pharmacological RINC therapy for hypertension was achieved through lifestyle changes such as a hypertension diet, physical exercise, stress management, and patient compliance with frequently regulating blood pressure (2) (3) .…”

Differences in explosive strength values for students of the faculty of physical education and sports (male) according to body mass index levels

“…Sports subjects (team sports games, combat sports, track and field) have higher explosive force values compared to physically active but nonsporting subjects, as a result of adaptive changes of the body [20]. A direct effect of physical effort and systematic training is the improvement of physical performance, as a result of morphological and functional adaptations to various demands [21,22,23]. However, the installation of muscle fatigue affects the performance related to the strength of the lower body, being found significantly lower values in the vertical and horizontal jumps after physical effort, compared to those before the effort.…”

Оцінка Якості Життя Хворих На Цукровий Діабет При Застосуванні Телереабілітації

“…Фізичні вправи впливають на діяльність нервової системи та стабілізують емоційний стан, що має велике значення в патогенезі ЦД. Методи реабілітації впливають також на показники серцево-судинної системи, оскільки сприяють профілактиці атеросклерозу та стабілізують діяльність серця (зниження артеріального тиску та частоти серцевих скорочень, зменшення індексу маси тіла, зниження холестерину та ліпопротеїдів низької щільності) [5].…”