Impact of Nano Hydroxyapatite, Nano Silver Fluoride and Sodium Fluoride Varnish on Primary Enamel Remineralization: An In Vitro Study

Nozari, Ali; Ajami, Shabnam; Rafiei, Azade; Niazi, Elmira

doi:10.7860/jcdr/2017/30108.10694

Cited by 55 publications

(99 citation statements)

References 27 publications

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“…Lowest values were reported for demineralized enamel (238.76 VHN). ese values are in agreement with previous reports that tested microhardness of intact and demineralized enamel [17][18][19][20][21]. Additionally, the present report tested also enamel after demineralization followed by remineralization treatment, showing intermediate values (278.97 VHN).…”

Section: Groupsupporting

confidence: 92%

“…Additionally, the present report tested also enamel after demineralization followed by remineralization treatment, showing intermediate values (278.97 VHN). To our knowledge, only few authors evaluated microhardness of enamel remineralized with nanohydroxyapatite serum [19] showing similar values. Previous studies evaluated other remineralizing agents such as fluoride varnish [18] or amorphous calcium phosphate [17] and showed a partial increase of microhardness values after remineralizing treatments, as in our study.…”

Section: Groupmentioning

confidence: 97%

“…As in previous reports that evaluated the microhardness of dental materials [17][18][19][20], each specimen's microhardness was determined with a microhardness tester (Isoscan HV2, LTF Spa, Antegnate, Bergamo, Italy) using a Vickers diamond indenter. ree indentations were made equally placed over a circle, each being no closer than 0.5 mm to the adjacent indentation, using a 25 g load with a 5 s dwell time [21].…”

Section: Microhardness Testmentioning

confidence: 99%

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Biomimetic Effect of Nano-Hydroxyapatite in Demineralized Enamel before Orthodontic Bonding of Brackets and Attachments: Visual, Adhesion Strength, and Hardness in In Vitro Tests

Scribante

Farahani

Marino

et al. 2020

BioMed Research International

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Dietary habits with high consumption of acidic food can induce in orthodontic patients an increased risk of demineralization lesions around orthodontic brackets and bands. The purpose of the present laboratory study is to assess the in vitro visual efficacy of a biomimetic nano-hydroxyapatite remineralizing solution in a hypomineralized enamel surface and its effect on adhesion of fixed orthodontic appliances and on enamel microhardness. Intact teeth were demineralized, and subsequently the areas of demineralization were visually recorded using a 0–100 scale. Subsequently, a remineralizing solution (Biorepair® Repair Shock Treatment) was applied for ten minutes once a day/for one week per month for a total remineralizing treatment of 3 months. Visual effects were recorded. Moreover, bond strength was recorded and adhesive remnant index scores were measured for both orthodontic brackets and composite attachments both before demineralization and after demineralization and application of remineralizing solution. Also, Vickers microhardness was measured. All data were submitted to statistical analysis. The application of remineralizing solution induced a significant in vitro reduction of demineralized areas after the first week of application. No significant differences between untreated enamel surfaces and remineralized surfaces were detected after 2 months of remineralizing treatment. Bond strength values were significantly reduced for both brackets and attachments after remineralizing treatment. However, attachments showed higher adhesion values than brackets in both conditions tested. Remineralized enamel showed significantly higher microhardness values than demineralized enamel and lower values than intact enamel.

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Section: Groupsupporting

confidence: 92%

Section: Groupmentioning

confidence: 97%

Section: Microhardness Testmentioning

confidence: 99%

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Biomimetic Effect of Nano-Hydroxyapatite in Demineralized Enamel before Orthodontic Bonding of Brackets and Attachments: Visual, Adhesion Strength, and Hardness in In Vitro Tests

Scribante

Farahani

Marino

et al. 2020

BioMed Research International

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“…In this study, premolars have been freshly extracted from patients (12)(13)(14) years old for standardization and free from any aging changes that may present in enamel surfaces.All premolars were selected free from caries and any anatomical and morphological anomalies or structural abnormality such as enamel hypoplasia, amelogenesis imperfecta which can affect scanning Electron microscope results (23 ) . Specimens were stored in normal saline at room temperature to prevent dehydration.…”

Section: Discussionmentioning

confidence: 99%

“…In vitro study was conducted on 2017 to determine the impact of Nano-Hydroxyapatite (NHAp), Nano Silver Fluoride (NSF) and Sodium Fluoride (NaF) varnishes on enamel remineralization, it was revealed that both NaF varnish and NHAp had similar effect in remineralizing initial enamel caries and that NSF have the greatest remineralization capability in comparison to the other two materials evaluated. (14,15) Until now From our knowledge's there is no study that evaluate and compare the effects of silver diamine fluoride commercial and lab prepared versus nano silver fluoride on demineralized human enamel surfaces. The null hypothesis was that there is no difference in remineralizing effect of these materials.…”

Section: Introductionmentioning

confidence: 99%

Comparative Evaluation of the Effects of Silver Diamine Fluoride (Commercial and Lab Prepared) versus Nano silver fluoride on Demineralized Human Enamel Surfaces (In Vitro Study)

Soud

Elsaied

Omar

2020

Egyptian Dental Journal

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Background: -To evaluate and compare the effects of Silver diamine fluoride (commercial and lab prepared) versus nano silver fluoride on demineralized human enamel surfaces.Materials and methods: -A total 20 Extracted premolars for orthodontic reasons were collected from the Outpatient Each premolar was sectioned buccolingually into two halves, to obtain (40) specimens. These halves were randomly allocated into 5 groups according to different treatment modalities.Group I included 8 specimens were left untreated (negative control), Group II included 8 specimens were treated with demineralizing solution, Group III included 8 specimens were treated by Silver diamine fluoride (commercial form) after demineralizing solution, Group IV included 8 specimens were treated with Silver diamine fluoride (lab prepared) after demineralizing solution and Group V included 8 specimens that were treated with Nano silver fluoride after demineralizing solution. Each half was evaluated by Environmental scanning electron microscope and Energy dispersive x-ray spectroscopy .Results: There were significant differences between groups at P-value (≤0.05) for Phosphrous, Calcium and Calcium/Phosphrous ratio except (Fluoide). The lowest value for elements was recorded in group (II) followed by control group and the highest value was recorded at group (V). Conclusion:Silver Diamine Fluoride (lab made) is as efficient as commercial one in remineralizing demineralized enamel surfaces. Nano Silver Fluoride is more efficient than Silver Diamine Fluoride (lab made & commercial) on demineralized enamel surfaces. (154)Asmaa Aly Abo El Soud, et al.

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Nano‐hydroxyapatite preparation for the remineralization of primary tooth enamel surface subjected to liquid medication: An observational study

Hassan

Jafar

Latif

2023

Health Science Reports

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Background and Aims Acid‐induced demineralization may be caused by the consumption of liquid medications routinely administered to children. Therefore, different remineralizing agents, such as fluorides and nano‐hydroxyapatite, have been added to oral care products to remineralize erosive lesions. This study was conducted to compare the effectiveness of 1% nano‐hydroxyapatite suspension and 2% sodium fluoride solution on the surface texture of primary teeth enamel previously exposed to liquid drugs. Methods Thirty posterior primary teeth were extracted and grouped depending on the remineralizing agent used: (A) nano‐hydroxyapatite and (B) sodium fluoride. Groups A and B were subjected to liquid medication in two subgroups: cephalexin (cephalexin monohydrate) and ParAzar (acetaminophen), followed by remineralization with 1% nano‐hydroxyapatite suspension and 2% sodium fluoride solution. An atomic force microscope was used to analyze the surface texture of the primary tooth enamel by measuring the roughness and waviness parameters of the tested surfaces. The examination was performed at baseline, 7 days after exposure to drugs, and after exposure to remineralizing agents. Results A significant difference in enamel surface roughness between nano‐hydroxyapatite‐treated surfaces and sodium fluoride‐treated surfaces was observed. A significant change was observed in the surface waviness of the primary enamel surface of sodium‐fluoride‐treated teeth that were subjected to cephalexin. Conclusion Routine use of liquid medications could have a negative impact on primary enamel surface topography, because the primary tooth enamel is less mineralized than permanent tooth enamel. Our results show that compared with a 2% sodium fluoride solution, a 1% nano‐hydroxyapatite suspension can be used for remineralizing and restoring defects of the enamel surface of primary teeth following exposure to liquid medication, thus reinforcing dental tissues with higher efficacy.

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Impact of Nano Hydroxyapatite, Nano Silver Fluoride and Sodium Fluoride Varnish on Primary Enamel Remineralization: An In Vitro Study

Cited by 55 publications

References 27 publications

Biomimetic Effect of Nano-Hydroxyapatite in Demineralized Enamel before Orthodontic Bonding of Brackets and Attachments: Visual, Adhesion Strength, and Hardness in In Vitro Tests

Biomimetic Effect of Nano-Hydroxyapatite in Demineralized Enamel before Orthodontic Bonding of Brackets and Attachments: Visual, Adhesion Strength, and Hardness in In Vitro Tests

Comparative Evaluation of the Effects of Silver Diamine Fluoride (Commercial and Lab Prepared) versus Nano silver fluoride on Demineralized Human Enamel Surfaces (In Vitro Study)

Nano‐hydroxyapatite preparation for the remineralization of primary tooth enamel surface subjected to liquid medication: An observational study

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