Impact of N-acetyl cysteine (NAC) chit Nanocomposite as antioxidant on broiler chicks

Abstract

Nutrients nano-forms in livestock's feed are mainly intended to increase the production performance, enhance immunity and antioxidant activities. The current experiment was undertaken by feeding 150 (divided to five group control, N-acetyl cysteine (NAC), NAC chit nano-composite (different levels (30, 60, 120 μg / kg diet)), one day old broiler chicks for 42 days. The effect of these additives as antioxidant on liver and kidney function tests of broiler chicks were investigated. The results were compared with those obtained from feeding another group of broiler chicks on the normal diet but after addition of commercial antioxidant, NAC (5.2g/kg feed). The results showed that chicken in the groups fed on (60,120 μg / kg feed) of NAC chit revealed significant (P< 0.05) improved antioxidant status, liver and kidney function indices as compared with control and the other dietary treated groups. Structure of mitochondria in HRTEM examination showed slight to moderate swelling due to increase of NAC chit concentration and found NAC chit appeared inside the mitochondria.

N-Acetylcysteine Alleviated the Deltamethrin-Induced Oxidative Cascade and Apoptosis in Liver and Kidney Tissues

“…One-day-old, apparently healthy, Cobb broiler chicks were purchased from the El-Wataniya Poultry Company (Egypt). Chicks were divided into four experimental groups; each was performed into three replicates of five chicks: The first group (control) received a basal diet without any treatments; The second group (NAC) fed on a diet supplemented with NAC, 5.2 g/kg diet [ 21 ]; The third group (DLM) fed on a diet contaminated with DLM 300 mg/kg diet [ 22 ]; The fourth group (DLM+NAC) fed on a diet mixed with DLM and NAC, at the same rates of the above-mentioned doses. …”