Impact of irradiation on the microbial ecology of foods

Ünlütürk, Sevcan

doi:10.1002/9781118823071.ch8

Cited by 5 publications

(3 citation statements)

References 109 publications

(129 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gamma rays can cause mutations in cell genes, resulting in an overexpressing of the secondary metabolites (Unluturk 2016 ) responsible for silica bioleaching as well as Ag salt reduction. Here, 200 Gy gamma radiation dose was shown to be optimal for increasing anti-bacterial activity of the biofabricated nanocomposite by irradiated F. oxysporum- fermented rice husk, with significant variations in the obtained ZoI values.…”

Section: Discussionmentioning

confidence: 99%

Novel fabrication of SiO2/Ag nanocomposite by gamma irradiated Fusarium oxysporum to combat Ralstonia solanacearum

2022

View full text Add to dashboard Cite

The bacterial wilt is a global destructive plant disease that initiated by the phytopathogenic Ralstonia solanacearum. This study display a novel biofabrication of silica/silver nanocomposite using Fusarium oxysporum-fermented rice husk (RH) under solid state fermentation (SSF). The biofabricated nanocomposite was characterized by XRD, UV–Vis. spectroscopy, DLS, SEM, EDX elemental mapping, and TEM analyses as well as investigated for anti-R. solanacearum activity. Response surface methodology was also processed for optimizing the biofabrication process and improving the anti-bacterial activity of the fabricated nanocomposite. Maximum suppression zone of 29.5 mm against R. solanacearum was reached at optimum RH content of 6.0 g, AgNO3 concentration of 2.50 mM, reaction pH of 6.3, and reaction time of 2 days. The anti-R. solanacearum activity of the fabricated nanocomposite was further improved by exposing the F. oxysporum strain to a gamma irradiation dose of 200 Gy. In conclusion, RH recycling under SSF by F. oxysporum could provide an innovative, facile, non-expensive, and green approach for fabricating SiO2/Ag nanocomposite that could be applied efficiently as an eco-friendly antibacterial agent to combat R. solanacearum in agricultural applications. Moreover, the developed method could serve as a significant platform for the designing of new nanostructures for broad applications.

show abstract

Section: Discussionmentioning

confidence: 99%

Novel fabrication of SiO2/Ag nanocomposite by gamma irradiated Fusarium oxysporum to combat Ralstonia solanacearum

2022

View full text Add to dashboard Cite

show abstract

“…Subjecting the microbial cells to radiation leads to physiological, chemical, and metabolic differences as radiation imposes an extra stress to cells disturbing their organization (Unluturk 2017). Microbial strain mutation can be achieved by exposing the microbial cells to chemical or physical agents (such as UV.…”

Section: Dendrimementioning

confidence: 99%

Microbial acetylcholinesterase inhibitors for Alzheimer’s therapy: recent trends on extraction, detection, irradiation-assisted production improvement and nano-structured drug delivery

Zaki

El‐Sayed

Elkodous

et al. 2020

Appl Microbiol Biotechnol

View full text Add to dashboard Cite

Neurodegenerative disorders especially Alzheimer's disease (AD) are significantly threatening the public health. Acetylcholinesterase (AChE) inhibitors are compounds of great interest which can be used as effective agents for the symptomatic treatment of AD. Although plants are considered the largest source for these types of inhibitors, the microbial production of AChE inhibitors represents an efficient, easily manipulated, eco-friendly, cost-effective, and alternative approach. This review highlights the recent advances on the microbial production of AChE inhibitors and summarizes all the previously reported successful studies on isolation, screening, extraction, and detecting methodologies of AChE inhibitors from the microbial fermentation, from the earliest trials to the most promising anti-AD drug, huperzine A (HupA). In addition, improvement strategies for maximizing the industrial production of AChE inhibitors by microbes will be discussed. Finally, the promising applications of nano-material-based drug delivery systems for natural AChE inhibitor (HupA) will also be summarized. Key Points • AChE inhibitors are potential therapies for Alzheimer's disease. • Microorganisms as alternate sources for prospective production of such inhibitors. • Research advances on extraction, detection, and strategies for production improvement. • Nanotechnology-based approaches for an effective drug delivery for Alzheimer's disease.

show abstract

“…Irradiation causes an extra stress to microbial cells. Exposing the microbial cells to radiation (as a mutagen), results in mutations due to chemical, physiological, and metabolic changes (Unluturk 2016). Additionally, irradiation mutagenesis could develop desired, modified and improved mutants (Koutchma 2009).…”

Section: Introductionmentioning

confidence: 99%

Response surface methodology‐mediated improvement of the irradiated endophytic fungal strain, Alternaria brassicae AGF041 for Huperzine A‐hyperproduction

Zaki

El-Shatoury

Ahmed

et al. 2020

Lett Appl Microbiol

View full text Add to dashboard Cite

Huperzine A (HupA) is an anti‐Alzheimer’s therapeutic and a dietary supplement for memory boosting that is extracted mainly from Huperziacae plants. Endophytes represent the upcoming refuge to protect the plant resource from distinction but their HupA yield is still far from commercialization. In this context, UV and gamma radiation mutagenesis of the newly isolated HupA‐producing Alternaria brassicae AGF041 would be applied in this study for improving the endophytic HupA yield. Compared to non‐irradiated cultures, UV (30–40 min, exposure) and γ (0·5 KGy, dose) irradiated cultures, each separately, showed a significant higher HupA yield (17·2 and 30·3%, respectively). While, application of a statistically optimized compound irradiation (0·70 KGy of γ treatment and 42·49 min of UV exposure, sequentially) via Response Surface Methodology (RSM) resulted in 53·1% production increase. Moreover, a stable selected mutant strain CM003 underwent batch cultivation using a 6·6 l bioreactor for the first time and was successful for scaling up the HupA production to 261·6 µg l−1. Findings of this research are demonstrated to be valuable as the employed batch fermentation represents a successful starting step towards the promising endophytic HupA production at an industrial scale.

show abstract

Impact of irradiation on the microbial ecology of foods

Cited by 5 publications

References 109 publications

Novel fabrication of SiO2/Ag nanocomposite by gamma irradiated Fusarium oxysporum to combat Ralstonia solanacearum

Novel fabrication of SiO2/Ag nanocomposite by gamma irradiated Fusarium oxysporum to combat Ralstonia solanacearum

Microbial acetylcholinesterase inhibitors for Alzheimer’s therapy: recent trends on extraction, detection, irradiation-assisted production improvement and nano-structured drug delivery

Response surface methodology‐mediated improvement of the irradiated endophytic fungal strain, Alternaria brassicae AGF041 for Huperzine A‐hyperproduction

Contact Info

Product

Resources

About