Impact of gender on vitamin D deficiency in morbidly obese patients: a cross-sectional study

Johnson, Line Kristin; Hofsø, Dag; Aasheim, Erlend T.; Tanbo, Tom; Holven, Kirsten B.; Andersen, Lene Frost; Røislien, Jo; Hjelmesæth, Jøran

doi:10.1038/ejcn.2011.140

Cited by 59 publications

(49 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the present study there was no significant difference in dietary vitamin D intake between the central obesity group and the control group and both groups tended to have a dietary intake of low vitamin D content, so that the most of the vitamin D was obtained from Mean vitamin D levels of the subjects with central obesity was lower than those in the control group. This is in line with the results of the study by Johnson et al (20) who reported that subjects with obesity had low levels of vitamin D, particularly in the males compared with the females, with an odds ratio of 1.41 (95% CI: 1.17-1.70). Other studies that showed low levels of vitamin D in subjects with obesity were among others the studies conducted by Shafinaz et al, (18) Oommen et al, (21) and Tosunbayraktar et al (22) In our study we found a mean adiponectin level of 4.7 ± 0.26 ng/mL in subjects with central obesity, which was significantly lower than the mean adiponectin level of 6.8 ± 0.72 ng/mL in the control group.…”

Section: Discussionsupporting

confidence: 82%

Decreased adiponectin level in adults with central obesity and low 25-hydroxy vitamin D level

et al. 2017

View full text Add to dashboard Cite

BACKGROUNDVitamin D insufficiency is associated with obesity and central obesity, which is in turn associated with the accumulation of visceral fat. Visceral fat secretes adiponectin which has a role in the pathogenesis of the metabolic syndrome, diabetes mellitus and cerebrovascular disease. The aim of this study was to determine the relationship between serum 25-hydroxy vitamin D [25(OH)D] level and adiponectin level in adults with central obesity.

show abstract

Section: Discussionsupporting

confidence: 82%

Decreased adiponectin level in adults with central obesity and low 25-hydroxy vitamin D level

et al. 2017

View full text Add to dashboard Cite

show abstract

“…A growing body of epidemiological evidence [7–11] suggests that a lower level of vitamin D is not only associated with increased obesity, but also with a greater risk for weight gain over time. In US whiten [12], Hispanic, and African-American [13] populations, a negative relationship between adiposity and serum 25(OH)D concentration has been established.…”

Section: Introductionmentioning

confidence: 99%

Serum Vitamin D is Low and Inversely Associated with LDL Cholesterol in the Kazak Ethnic Population: A Cross-Sectional Study

Zhang

Liu

et al. 2014

Med Sci Monit

View full text Add to dashboard Cite

BackgroundAccumulating evidence suggests that low concentrations of serum 25(OH)D is coupled with increased risks of hypertension, obesity, and cardiovascular disease. However, this relationship has not been established in populations with very low levels of 25(OH)D. Therefore, the aim of our study was to clarify the associations between 25(OH)D and blood pressure, obesity, sex, and lipid profiles in the Kazak ethnic population, who have an extremely low level of 25(OH)D.Material/MethodsA multistage-cluster sampling survey was carried out for residents with Kazak ethnicity in Xinjiang, China. Anthropometric measurements of each participant were taken and the concentrations of 25(OH)D, calcium, alkaline phosphatase, and lipid profiles were measured. Individuals were classified into different groups in terms of vitamin D status, degree of adiposity, presence of hypertension, and other comorbidities.ResultsThe madian concentration of 25(OH)D was 16.2 (11.8–20.5) ng/mL and the prevalence of vitamin D deficiency was 72.4% in this Kazak population (n=928, 59.0% women). Females had a lower 25(OH)D concentration than males – 14.6 (10.5–19.4) ng/mL vs. 17.7 (14.8–22.5) ng/mL, P<0.001. The subjects were classified into 3 groups according to their vitamin D status. There were significant differences in BMI (P=0.046), waist circumference (P=0.037), hip circumference (P=0.003), systolic BP (P=0.035), and LDL cholesterol (P=0.008) among the groups after adjustment for sex and age. On the other hand, there was no significant difference in vitamin D levels between groups with or without hypertension (P=0.586), and groups with or without obesity (P=0.639). A multifactor-regression analysis revealed that every increment of 1mg/dL in LDL cholesterol was associated with a 1.0 ng/mL decline in serum 25(OH)D.ConclusionsThe insufficiency of vitamin D is highly prevalent in Kazaks. Sex, LDL cholesterol, and hip circumference are 3 variables strongly associated with serum 25(OH)D concentration. In a population with low levels of 25(OH)D, the negative relationship between obesity and serum 25(OH)D, a common finding from most previous studies, could not be established.

show abstract

“…28 A large cross-sectional study of 2,026 severely obese Norwegian adults found that about onehalf were vitamin D deficient, with male gender associated with a significantly greater odds of vitamin D deficiency. 29 Data from NHANES also demonstrate a strong association between higher 25(OH)D and lower percent body fat, particularly among patients who are centrally obese. 8 Nutritional deficiencies, compounded by higher intake of calorie-dense foods lacking nutrient value and limited access to unprocessed nutritious foods, may be important contributing factors in select obese and minority populations from disadvantaged neighborhoods.…”

Section: ■■ Discussionmentioning

confidence: 99%

Treatment of Vitamin D Deficiency Within a Large Integrated Health Care Delivery System

Stratton-Loeffler¹,

Lo²,

Hui³

et al. 2012

JMCP

View full text Add to dashboard Cite

show abstract

Impact of gender on vitamin D deficiency in morbidly obese patients: a cross-sectional study

Cited by 59 publications

References 46 publications

Decreased adiponectin level in adults with central obesity and low 25-hydroxy vitamin D level

Decreased adiponectin level in adults with central obesity and low 25-hydroxy vitamin D level

Serum Vitamin D is Low and Inversely Associated with LDL Cholesterol in the Kazak Ethnic Population: A Cross-Sectional Study

Treatment of Vitamin D Deficiency Within a Large Integrated Health Care Delivery System

Contact Info

Product

Resources

About