Impact of Female Sex on Death and Bleeding After Fibrinolytic Treatment of Myocardial Infarction in GUSTO V

Reynolds, Harmony R.

doi:10.1001/archinte.167.19.2054

Cited by 64 publications

(40 citation statements)

References 45 publications

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“…Compared with male patients, women with CAD have a worse prognosis in the early phase after acute cardiovascular events, 1,2 which may be related to older age at the time of myocardial infarction (MI) and more complex comorbidities, such as diabetes, renal failure, and arterial hypertension. 3,4 Additionally, higher periprocedural bleeding rates, 5 underuse of glycoprotein IIb=IIIa receptor blockers, 6 and a lower rate of revascularization 7 have been reported.…”

Section: Introductionmentioning

confidence: 99%

Elevated Risk Profile of Women in Secondary Prevention of Coronary Artery Disease: A 6-Year Survey of 117,913 Patients

Reibis¹,

Bestehorn

Pittrow³

et al. 2009

Journal of Women's Health

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Section: Introductionmentioning

confidence: 99%

Elevated Risk Profile of Women in Secondary Prevention of Coronary Artery Disease: A 6-Year Survey of 117,913 Patients

Reibis¹,

Bestehorn

Pittrow³

et al. 2009

Journal of Women's Health

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“…Female sex and older age have consistently been linked with an increased risk of ventricular septal rupture after infarction in previous studies [8][9][10]. Matrix metalloproteinase-9 (MMP-9), the enzyme most frequently implicated in myocardial rupture and which has been reported to be elevated in unstable angina, may be playing a role in the absence of frank infarction [11].…”

Section: Discussionmentioning

confidence: 99%

Ventricular septal rupture complicating acute myocardial infarction following percutaneous coronary intervention

Rajan

Padmaja

Pillai

et al. 2012

IMAS

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Ventricular septal rupture (VSR) is a rather rare, but at the same time very dreadful complication of acute myocardial infarction in the percutaneous coronary intervention (PCI) era and only limited evidence exist on the optimal treatment of this critical medical condition. VSR is less common following successful early thrombolysis and PCI occurring in myocardium supplied by infarct-related artery (IRA). We report two well-documented cases of successful VSR treatment which will provide valuable information for clinical practice especially due to the longtem follow-up. Both cases underwent delayed elective surgical closure of VSR. This report clearly describes the incidence, potential risks and timing of occurrence, clinical features, and outcomes of ventricular septal rupture complicating acute myocardial infarction (AMI) after PCI. Hence the topic of this report is of great importance. Although the prognosis of patients who develop VSR is generally grave without immediate surgical repair, both our patients remained hemodynamically stable at discharge and during follow-up of more than 4 years.Keywords: ventricular septal rupture, acute myocardial infarction, percutaneous coronary intervention c a s e r e p o r t

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“…Observational and trial data indicate that women are less likely than men to be selected for coronary angiography after presentation with chest pain in the outpatient setting, in emergency departments, with non-ST-segment elevation acute coronary syndromes (NSTE ACS) [ 1 ], and during and after ST-segment elevation myocardial infarction (STEMI) [ 2 ]. The lower rates of use of angiography in women are independent of older age and levels of risk.…”

Section: Selection For Angiographymentioning

confidence: 99%

“…As in other clinical circumstances, women are less likely to be referred for angiography and revascularization after thrombolytic treatment of STEMI [ 2 ]. Routine angiography after thrombolysis has never been shown to be benefi cial.…”

Section: Angiography and Revascularization After Thrombolysismentioning

confidence: 99%

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Percutaneous and surgical revascularization procedures in women

Reynolds

2008

Curr Cardio Risk Rep

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There has been an important increase in the availability of sex-specifi c data on the use and outcomes of revascularization procedures in women over the past year. Our understanding of the impact of female sex on the use and outcomes of revascularization procedures is limited by bias against inclusion of women in randomized trials and by the fact that coronary angiography, a necessary step in the evaluation of any patient for revascularization, is performed less frequently in women. Available information suggests that women and men usually receive equal benefi t from revascularization procedures. This article reviews recent literature on the use of invasive coronary procedures in women.

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Impact of Female Sex on Death and Bleeding After Fibrinolytic Treatment of Myocardial Infarction in GUSTO V

Cited by 64 publications

References 45 publications

Elevated Risk Profile of Women in Secondary Prevention of Coronary Artery Disease: A 6-Year Survey of 117,913 Patients

Elevated Risk Profile of Women in Secondary Prevention of Coronary Artery Disease: A 6-Year Survey of 117,913 Patients

Ventricular septal rupture complicating acute myocardial infarction following percutaneous coronary intervention

Percutaneous and surgical revascularization procedures in women

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