Impact of an antimicrobial formulary and restriction policy in the largest hospital in Italy

The impact of an intensive antimicrobial control program in a Taiwanese medical center

“…Increased usage of ciprofloxacin (by 40%) and meropenem (by 50%) may be attributable to the prescription preferences of physicians or to the trend towards increased resistance rates of pathogens to ciprofloxacin. Furthermore, the usage of two glycopeptide antibiotics was similar to, or less than, the DDD/100 PDs found in the Bassetti et al [27] study in Italy. More conservative use, and close monitoring, of glycopeptide antibiotics should be adopted within this medical center.…”

“…Nevertheless, the absolute consumption of cefazolin was 20.3-22.3, which was still ten times higher than that reported in Italy [27].…”

Glycopeptide Use at Four University Hospitals in Southern Germany

“…Vancomycin use in a French university hospital during 1999 was 1.19 DDD/100 patient days [22]. In a large Italian teaching hospital glycopeptide use ranged between 2.44 and 2.74 DDD/100 patient days [23]. According to the only recent study from Germany we are aware of, estimated vancomycin use densities at a university hospital were 2.69 DDD/100 patient days before and 2.15 DDD/100 patient days after a restriction program, respectively [24].…”

Impact of an Antimicrobial Stewardship Initiative on Ertapenem Use and Carbapenem Susceptibilities at Four Community Hospitals

“…Antimicrobial stewardship programs, which often track antibiotic prescribing trends and assess for optimal use, have demonstrated the ability to improve patient safety, reverse antimicrobial resistance rates, and decrease healthcare expenditures [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. With the urgent threat from carbapenem-resistant organisms, the utilization of carbapenems and other broad-spectrum antibiotics has drawn attention [18].…”