The impact of an intensive antimicrobial control program in a Taiwanese medical center

Wu, Tzong–Lin; Wang, Chun Yu; Jang, Tsrang Neng; Huang, Chiung Chun

doi:10.1007/s11096-006-9035-5

Cited by 15 publications

(17 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A hospital in Italy reported an overall decrease of 8.5% in antibiotic use in the first year following adoption of an antibiotic control programme [24]. A hospital in Taiwan that adopted a policy similar to ours reported a decline of 13.2% in DDD/100 PD for parenteral antimicrobials immediately before and after implementation [25]. A novel feature of our study is that it spans a 9-year period following the implementation of an antimicrobial control policy, allowing an evaluation of the extent to which the provisions have been followed over time.…”

Section: Discussionsupporting

confidence: 55%

Decline in the incidence of healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) correlates with deceased antimicrobial consumption at a tertiary care hospital in Taiwan, 2001–2009

Lee

Tsao

Lin

et al. 2010

International Journal of Antimicrobial Agents

View full text Add to dashboard Cite

The present study investigated the long-term impact of antibiotic use policy on the rates of consumption (expressed as daily-defined doses/1000 patient-days) of various parenteral antibiotics and on the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) and the incidence of healthcare-associated MRSA (HA-MRSA) infection at a tertiary care hospital from 2001 to 2009. During this time, consumption of all antimicrobials for systemic use decreased by 33%. This change was driven by a 44% decrease in the consumption of unrestricted antibacterials, which was offset by a 42% increase in the consumption of restricted agents. The trends in MRSA prevalence (number of isolates/1000 patient-days) and HA-MRSA incidence (number of HA-MRSA-infected persons/1000 patient-days) correlated with the trend in overall consumption of antimicrobials. Significant positive correlations were observed between MRSA prevalence and the consumption of extended-spectrum and β-lactamase-resistant penicillins, first-generation cephalosporins, macrolides, lincosamides and streptogramins, aminoglycosides, and glycopeptides. Significant positive correlations were found between the incidence of HA-MRSA infection and the consumption of tetracyclines, extended-spectrum and β-lactamase-resistant penicillins, sulfonamides and trimethoprim, macrolides, lincosamides and streptogramins, and aminoglycosides. In conclusion, we have documented the ongoing successful reduction in total consumption of antimicrobials associated with a decrease in the incidence of HA-MRSA and the prevalence of MRSA over a 9-year period.

show abstract

Section: Discussionsupporting

confidence: 55%

Decline in the incidence of healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) correlates with deceased antimicrobial consumption at a tertiary care hospital in Taiwan, 2001–2009

Lee

Tsao

Lin

et al. 2010

International Journal of Antimicrobial Agents

View full text Add to dashboard Cite

show abstract

“…For example, the trend of resistance in the intensive care may differ markedly from the general wards. Although there are publications where no impact on antimicrobial resistance rates were reported, 13 , 18 , 40 , 51 the general trend has been that implementation of ASPs has led to reduction of resistance, 50 , 52 - 56 but publication bias cannot be excluded.…”

Section: Outcomes For Antimicrobial Stewardship Interventionsmentioning

confidence: 99%

Antimicrobial stewardship

Chung

Yeo

et al. 2013

Virulence

View full text Add to dashboard Cite

Antimicrobial stewardship is an emerging field currently defined by a series of strategies and interventions aimed toward improving appropriate prescription of antibiotics in humans in all healthcare settings. The ultimate goal is the preservation of current and future antibiotics against the threat of antimicrobial resistance, although improving patient safety and reducing healthcare costs are important concurrent aims. Prospective audit and feedback interventions are probably the most widely practiced of all antimicrobial stewardship strategies. Although labor-intensive, they are more easily accepted by physicians compared with formulary restriction and preauthorization strategies and have a higher potential for educational opportunities. Objective evaluation of antimicrobial stewardship is critical for determining the success of such programs. Nonetheless, there is controversy over which outcomes to measure and there is a pressing need for novel study designs that can objectively assess antimicrobial stewardship interventions despite the limitations inherent in the structure of most such programs.

show abstract

“…Various studies have evaluated the impacts of antimicrobial stewardship programmes. 8 However, there are few studies on the long-term effects of antimicrobial management in China. In this retrospective study, the effects of national plans on the promotion of the rational use of antibacterial agents in the hospital were assessed by investigating the use of antibiotics from 2011 to 2014.…”

Section: What Is Known and Objectivementioning

confidence: 99%

Impact of an antimicrobial stewardship programme on antibiotic usage and resistance in a tertiary hospital in China

Zhang

Chen

2017

J Clin Pharm Ther

View full text Add to dashboard Cite

show abstract

The impact of an intensive antimicrobial control program in a Taiwanese medical center

Cited by 15 publications

References 22 publications

Decline in the incidence of healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) correlates with deceased antimicrobial consumption at a tertiary care hospital in Taiwan, 2001–2009

Decline in the incidence of healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) correlates with deceased antimicrobial consumption at a tertiary care hospital in Taiwan, 2001–2009

Antimicrobial stewardship

Impact of an antimicrobial stewardship programme on antibiotic usage and resistance in a tertiary hospital in China

Contact Info

Product

Resources

About