Immunosensors in medical diagnostics - major hurdles to commercial success

Manning, Brendan D.; Maley, Thomas C.

doi:10.1016/0956-5663(92)85037-b

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A Immunoassays1

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1997

2010

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Cited by 6 publications

(1 citation statement)

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“…Unfortunately, the cost, size, and mechanical complexity of immunosensors often precludes their use in settings other than clinical laboratories, where they provide only minimal advantages over existing techniques [3].…”

Section: A Immunoassaysmentioning

confidence: 99%

A high-sensitivity micromachined biosensor

Baselt¹

1997

Biosensors and Bioelectronics

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Section: A Immunoassaysmentioning

confidence: 99%

A high-sensitivity micromachined biosensor

Baselt¹

1997

Biosensors and Bioelectronics

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Pollution Treatment, Remediation and Sensing

Sugunan

Dutta

2010

Nanotechnology

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Environmental pollution has become a matter of grave concern and it is clear that the issue must be dealt with early in the 21st century, before it is too late. Nanotechnology is a promising discipline that shows promise of impacting diverse fields, including environmental pollution. In this chapter, various types of environmental pollution and the scope of nanotechnology in addressing these problems are discussed. The literature on the treatment, remediation and detection (sensors) of various environmental pollutants is surveyed, with focus on the timely detection of the pollutants. Cost‐effective strategies and niche approaches that offer good potential for application not only in real‐time pollution detection, but also in pollution treatment and remediation, are discussed.

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Advances in electrochemical immunosensors

Skládal

1997

Electroanalysis

194

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The developments in the field of electrochemical immunosensors and immunoassays are reviewed. The enzyme labels suitable for amperometric, potentiometric and conductimetric detection are mentioned. Indirect immunosensors (i.e., that involving enzymatic or electroactive labels) use either heterogeneous or homogeneous formats. Immunoelectrodes are based on conventional electrodes, semiconductor devices are represented by ISFETs and light addressable potentiometric sensors (LAPS). Direct label-free monitoring of immunoreactions is demonstrated on capacitance systems and pulsed detection using polypyrrole-modified electrodes. The approaches to regeneration of sensing surfaces are discussed. Examples are given on applications of electrochemical immunodevices in clinical medicine and in environmental monitoring.

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Immunosensors in medical diagnostics - major hurdles to commercial success

Cited by 6 publications

References 2 publications

A high-sensitivity micromachined biosensor

A high-sensitivity micromachined biosensor

Pollution Treatment, Remediation and Sensing

Advances in electrochemical immunosensors

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