Immunomodulatory and antiarthritic activities of Smilax zeylanica

Babu, Pva; Ashwini, TS; Krishna, Marothu Vamsi; Raju, M. Ganga

doi:10.5138/09750185.1963

Cited by 5 publications

(3 citation statements)

References 9 publications

(9 reference statements)

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“…If pollination occurs, the plant will produce a bright red to blue-black spherical berry fruit about 5-10 mm in diameter that matures in the fall (Jena 2011). S. zeylanica also often founded in temperature zone, tropics and subtropics worldwide (Babu 2017).…”

Section: Smilax Zeylanica Lmentioning

confidence: 99%

The diversity of Smilax (Smilacaceae) in Besiq-Bermai and Bontang Forests, East Kalimantan, Indonesia

Sofiah

Sulistyaningsih

2018

Biodiversitas

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Sofiah S, Sulistyaningsih LD. 2019. The diversity of Smilax (Smilacaceae) in Besiq-Bermai and Bontang Forests, East Kalimantan, Indonesia. Biodiversitas 20: 279-287. The genus Smilax has taxonomic complexity problems and spacious distribution. Taxonomic study to reveal the diversity of Smilax species had been done in some regions, such as America, China, Japan, Thailand, and Indonesia. However, there is lack of information of Smilax species diversity in Kalimantan especially in East Kalimantan which lies in Sundaland biogeographic. This study was carried out to explore and record the diversity of Smilax species including the ecological and environmental data in Besiq-Bermai and Bontang forests in East Kalimantan, Indonesia. This research conducted on February and August in 2012 and July-August 2015 using exploration methods. Purposive random sampling was used to do the botanical sampling. The principal component analysis (PCA) was performed to determine the relationships between environmental components and Smilax species occurrences. There were five species of Smilax which were housed in those forests in East Kalimantan, namely, Smilax leucophylla Blume, Smilax gigantea Merr., Smilax odoratissima Blume, Smilax zeylanica L., and Smilax modesta A.DC. Smilax leucophylla and Smilax zeylanica are the most widely used by the local people for medicine. The taxonomic description, distribution, use, and vernacular name were given. The environmental factors that contribute significantly to Smilax's growing environment are temperature and light intensity.

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Section: Smilax Zeylanica Lmentioning

confidence: 99%

The diversity of Smilax (Smilacaceae) in Besiq-Bermai and Bontang Forests, East Kalimantan, Indonesia

Sofiah

Sulistyaningsih

2018

Biodiversitas

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“…Antioxidant property of roots and rhizomes of Smilax zeylanica and concluded that the methanolic extract showed potential scavenging effect against DPPH [14].…”

Section: Antioxidant Activitymentioning

confidence: 99%

Smilax zeylanica: An overview

Sharma¹,

Tyagi²,

Majhi³

2018

IJRDPL

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Available online on:15.01.2018@http://ijrdpl.com http://dx.doi.org/10.21276/IJRDPL. 2278-0238.2018.7(1). [2893][2894][2895] ABSTRACT: Smilax zeylanica is a plant species in the genus smilax. Its leaves and roots are used for medicinal purposes. The plant is widespread in India, and native in other parts of the Indian subcontinent as well as in Myanmar, Malaysia, java and islands. It is perennial, dioecious shrub of climbing nature. Leaves of Smilax zeylanica are found in various shapes like ovate, elliptic, oblanceolate which are generally round at base. It is known with different names like in Hindi-Chobchini, Bhitura, Kumarika and Ramdatun; Sanskrit: Chopachinee, Vanamadhusnuhi: Tamil-ayadi, Tirunamappalai. The plants contain 1-3% steroidal Saponins, phytosterols, starch, resin, sarsapic acid and minerals. Leaves and roots contain diosgenin. It is traditionally used for ulcers. Antiulcer activity of Smilax zeylanica it is one of the larval host plants of the butterfly Zesius chrysomallus. It is one of the safe and efficacious medicinal used traditionally for the treatment of various ailments. As per Ayurveda the plant is useful against skin diseases pitta, insanity, diarrhea, colic, vata, syphilis, gonorrhea, fever, arthritis, leucorrhoea, impotency and general weakness etc. its roots are used as substitute for sarsaparilla. It also possesses many pharmacological activities such as antidiabetic, anticancer, anthelmintic, antioxidant, antiepileptic, hepatoprotective, pesticidal, immunomodulatory, antibacterial and antarthritic.

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“…S. zeylanica is used ethnomedicinally for the treatment of different conditions such as abscesses, boils, dysentery, psoriasis, rheumatism, skin diseases, swellings, toothache and venereal diseases [6][7][8][9][10] . This plant is shown to exhibit several bioactivities such as antimicrobial and analgesic 11,12 , antioxidant 12,13 , cytotoxic 13 , immunomodulatory and antiarthritic 14 , anthelmintic 15 , antipyretic 16 , anticonvulsant 16 , antidiabetic 17 , cytoprotective 18 , hepatoprotective 19 , antiinflammatory 20 , antiepileptic 21 , pesticidal 22 , thrombolytic 23 , and antidepressant 24 activities. Therefore, the present investigation focused to evaluate the invivo antioxidant potential of ethanolic extract of roots of Smilax zeylanica in different screening methods.…”

Section: Introductionmentioning

confidence: 99%

In vivo antioxidant activity of Ethanolic extract from root of Smilax zeylanica on Aluminium Chloride Induced oxidative stress in Wistar rats

Senthil

Kalaichelvan

Muthu

2018

J. Drug Delivery Ther.

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Objective: The objective of the present study was to investigate the Evaluation of In vivo antioxidant activity of Ethanolic extract of root of Smilax zeylanica(EESZ) on Aluminium Chloride Induced apoptosis suppressing oxidative stress in Wistar rats. Materials and Methods: The ethanolic extract from the roots of S. china by hot continuous percolation method. The rats were divided into 5 groups and each group consists of 6 animals. Rats were treated with EESC for 150 and 300 mg/ kg of body weight and piracetam, 0.5 mg/ kg of body weight for 14 successive days after inducing oxidative stress with aluminium chloride (100 mg/ kg of body weight) for 60 days. The lipid peroxidation level (TBARS) and antioxidant activities like Superoxide dismutase (SOD), Catalase (CAT) and reduced Glutathione (GSH) were estimated in rats. Results: AlCl3 induced rats showed increased the TBARS and decreased the antioxidant enzymes like Superoxide dismutase (SOD), Catalase (CAT) and reduced Glutathione (GSH) when compared with the control group. The EESZ at higher dose 300 mg/ kg of body weight animals were significantly (P < 0.001) reduced the TBARS and increased the anti oxidant enzymes Superoxide dismutase (SOD), Catalase (CAT) and reduced Glutathione (GSH) when compared with the AlCl3 treated group Conclusion: Findings of the present study revealed that Ethanolic extract from roots of Smilax zeylanica may be used as a significant source of natural antioxidant, which might be helpful in preventing the progress of various oxidative stresses. Keywords: S. zeylanica, antioxidant, ethanolic extract, TBARS, rats.

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Immunomodulatory and antiarthritic activities of Smilax zeylanica

Cited by 5 publications

References 9 publications

The diversity of Smilax (Smilacaceae) in Besiq-Bermai and Bontang Forests, East Kalimantan, Indonesia

The diversity of Smilax (Smilacaceae) in Besiq-Bermai and Bontang Forests, East Kalimantan, Indonesia

Smilax zeylanica: An overview

In vivo antioxidant activity of Ethanolic extract from root of Smilax zeylanica on Aluminium Chloride Induced oxidative stress in Wistar rats

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