Immunomodulatory action of propolis. V. Anticomplementary activity of a water-soluble derivative

Ivanovska, Nina; Dimov, Valentin; Pavlova, Stephanie T.; Bankova, Vassya; Попов, Симеон

doi:10.1016/0378-8741(95)01273-g

Cited by 25 publications

(18 citation statements)

References 13 publications

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“…It is likely that flavonoids are the active ingredients in propolis, considering the pharmacological roles of these compounds. Esters of cinnamic and cafferic acids are among the flavonoids in propolis that have been found to play various physiological and pharmacological roles (Miyataka et al 1997;Burdock 1998;Lee et al 2005) such as anticancer, antibacteria, antivirus, antibiotic, anti-repugnance, antifungal, antioxidant and cure for other allergic dermatitis (Ivanovska et al 1995;Choi et al 2006;Mani et al 2006). Similar to the trend in lysozyme activities and hematocrit in this study, high inclusion of flavonoids has been reported to decrease hematocrit value (Hasumura et al 2004).…”

Section: Discussionsupporting

confidence: 86%

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

et al. 2011

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This study was conducted to investigate the effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica, in order to evaluate its bioavailability as a feed additive for this species. A total of 540 fish averaging 7.7 ± 0.22 g (mean ± SD) were randomly distributed into 18 tanks in groups of 30, and each tank was then randomly assigned to one of three replicates of six diets containing 0 (P 0 ), 0.25 (P 0.25 ), 0.5 (P 0.5 ), 1.0 (P 1 ), 2.0 (P 2 ) and 4.0 (P 4 ) % dietary propolis. At the end of 12 weeks of feeding trial, weight gain (WG), specific growth rate (SGR), feed efficiency (FE) and protein efficiency ratio (PER) of fish fed P 0.5 diet were significantly higher than those of fish fed P 0 , P 1 , P 2 and P 4 diets (P \ 0.05). These parameters were 148.9%, 0.72% day -1 , 94.4% and 2.9, respectively for fish fed P 0.5 diet. Serum lysozyme activity of fish fed P 0.5 (105.7 units mL -1 ) and P 1 (106.0 units mL -1 ) diets were significantly higher than those of fish fed P 0 , P 0.25 , P 2 and P 4 diets. Mucus lysozyme activity of fish fed P 1 (8.4 units 10 cm -2 ) diet was significantly higher than those of fish fed P 0 , P 2 and P 4 diets. Results indicated that the optimum dietary propolis supplementation levels could be 0.25-0.5% for optimum growth and feed efficiency, and 0.5-1% for enhanced immune responses and disease resistance in eel, A. japonica. This study may suggest that the dietary propolis level for the optimum immune responses could be higher than the level for the optimum growth of eel.

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Section: Discussionsupporting

confidence: 86%

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

et al. 2011

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“…injection with WEP. Only one study has shown changes in the cellularity of mice injected with water-soluble derivatives of propolis, in which the number of leucocytes and the percentage of CD8 C and CD4 C cells were significantly increased [25]. In our study, seabream HK leucocyte phagocytosis, cytotoxicity and peroxidase content were slightly enhanced while respiratory burst was decreased.…”

Section: Discussionmentioning

confidence: 50%

“…EEP produced an increase after only one day, while WEP only showed an effect after 5 days. Other studies describe increments in the mobility, fungicidal and tumoricidal activities, and in the production of IL-1, TNF and lymphocyte activating factors of mammalian macrophages after in vitro or in vivo treatment with propolis, or some of its components [4,5,7,25]. The role played by propolis in one of the most important functions of macrophages, the production of free radicals, is not clear.…”

Section: Discussionmentioning

confidence: 94%

In vivo effects of propolis, a honeybee product, on gilthead seabream innate immune responses

Cuesta

Rodrı́guez

Meseguer

2005

Fish & Shellfish Immunology

116

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“…Grange e Davey (1990) A própolis é utilizada popularmente no tratamento de infecções, em problemas de pele e, também, como antiviral e anti ulceroso (Reis et al, 2000;Khalil, 2006). Ela estimula o sistema imunológico (Kosonocka, 1991;Ivanovska et al, 1995;Sforcin, 1996;Dos Santos et al, 2003;Khalil, 2006), é cicatrizante em escaras de decúbito (Azevedo et al, 1986) e apresenta atividade antibiótica frente às bactérias gram positivas (Grange;Davey 1990;Bankova et al, 1999;Kujumgiev et al, 1999;Fernandes Junior et. al., 2005).…”

Section: Introductionunclassified

Método para avaliação e pesquisa da atividade antimicrobiana de produtos de origem natural

Packer¹,

Luz²

2007

Rev. bras. farmacogn.

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RESUMO:As exigências do mercado consumidor induzem a indústria cosmética a formular produtos seguros cada vez menos agressivos e naturais. Durante a formulação para tais apelos a difi culdade maior encontra-se em conservar o produto fi nal. Com este objetivo avaliamos os óleos: de copaíba, alecrim, melaleuca, alho, andiroba; própolis, e dois ingredientes de origem natural: um ingrediente multifuncional extraído de folhas de oliva e o farnesol que estão disponíveis e são fornecidos à indústria cosmética, com a fi nalidade de comprovar a ação dos mesmos. O método de escolha foi o de ágar em placa com orifício modifi cado. As cepas selecionadas foram Staphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 8739), Pseudomonas aeruginosa (ATCC 9027) e Candida albicans (ATCC 10231). Dentre as amostras analisadas os melhores resultados foram obtidos com os óleos de melaleuca e alecrim que apresentaram atividade bacteriostática e fungistática para as quatro cepas em questão.Unitermos: Própolis, óleo de melaleuca, óleo de alecrim; óleo de copaíba, óleo de alho, óleo de andiroba.ABSTRACT: "Evaluation and research method for natural products inhibitory activity". The consumer market requirement induces the cosmetic industry to generate safer and less aggressive products including the natural products. Within the natural products formulation process, the most demanding challenge is the fi nal product conservation. In order to cope with the conservation factor, some natural oils (copaiba, rosemary, melaleuca, garlic, andiroba), propolis and two natural ingredients (one multifunctional ingredient extracted from olive leaves and farnesol) which are available and usually supplied to the cosmetic industry, were considered in this analysis. The chosen method was the agar in plaque with modifi ced hole. The chosen microorganisms were: Staphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 8739), Pseudomonas aeruginosa (ATCC 9027) and Candida albicans (ATCC 10231). The best results were achieved by melaleuca and rosemary oils, which showed bacteriostatic and fungistatic activity against the four microorganisms.Keywords: Propolis, melaleuca oil, rosemary oil, copaiba oil, garlic oil, andiroba oil. INTRODUÇÃOO consumidor tem se tornado cada vez mais exigente e mais criterioso com a qualidade do produto que consome. É crescente a sua preocupação em fazer uso de produtos menos agressivos de origem natural ou o mais próximo possível desta origem. Esta é a realidade à qual está submetida, também, a indústria cosmética; formulação de produtos naturais, portanto a não inclusão de matérias primas sintéticas para, por exemplo, conservação do produto fi nal. Neste quesito são poucas as formulações que resistem à primeira inoculação quando do Teste de Desafi o do Conservante. Por tal motivo remetese à pesquisa de produtos extraídos de fi toterápicos e produtos naturais com valor conhecido, comprovado ou não, que são ofertados à indústria cosmética.Um dos melhores exemplos são produtos que contenham em seus constituintes, fl avonóides. Flav...

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Immunomodulatory action of propolis. V. Anticomplementary activity of a water-soluble derivative

Cited by 25 publications

References 13 publications

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

Effects of dietary propolis supplementation on growth performance, immune responses, disease resistance and body composition of juvenile eel, Anguilla japonica

In vivo effects of propolis, a honeybee product, on gilthead seabream innate immune responses

Método para avaliação e pesquisa da atividade antimicrobiana de produtos de origem natural

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