Immunological study of pulmonary aspergilloma

Ávila, Ramiro

doi:10.1136/thx.23.2.144

Cited by 12 publications

(9 citation statements)

References 9 publications

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“…Electrophoresis was done for 30 minutes with a constant 42 5 mA current, after which the slides were washed, dried, and stained with Amidoschwartz lOB (Avila, 1968).…”

mentioning

confidence: 99%

Respiratory disease caused by synthetic fibres: a new occupational disease.

Pimentel¹,

Ávila²,

Lourenço³

1975

Thorax

119

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Seven patients exposed to the inhalation of synthetic fibres presented with various bronchopulmonary diseases, such as asthma, extrinsic allergic alveolitis, chronic bronchitis with bronchiectasis, spontaneous pneumothorax, and chronic pneumonia. The histological features are described and an attempt has been made to set up immunological techniques for the diagnosis. A series of histochemical techniques, based on textile chemistry, are proposed for the identification of the inclusions found in bronchopulmonary lesions. The results of the experimental production of the disease in guinea-pigs by the inhalation of synthetic fibre dusts are presented. The prognosis of these cases is good in the acute or recently established cases but is poor when widespread and irreversible fibrosis has set in. The authors consider that pulmonary disease due to inhaled particles is probably set off by an individual factor, possibly immunological.

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“…Electrophoresis was done for 30 minutes with a constant 42 5 mA current, after which the slides were washed, dried, and stained with Amidoschwartz lOB (Avila, 1968).…”

mentioning

confidence: 99%

Respiratory disease caused by synthetic fibres: a new occupational disease.

Pimentel¹,

Ávila²,

Lourenço³

1975

Thorax

119

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“…(1964) state that it is unusual for an aspergilloma to be present in people with a negative precipitin test since the fungal mass of the aspergilloma provides abundant antigenic stimulation. The significance of precipitating antibodies to Aspergillus has been confirmed by Avila (1968), British Tuberculosis Association (1968) and Villar 1'1 al. (1967).…”

Section: Immunologymentioning

confidence: 84%

Pulmonary Aspergilloma

Joynson

1977

Int J Clinical Practice

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Mycotic infections continue to play an increasingly important role in the practice of medicine and particula rly in pulmonary disease.The histo ry of Aspergillus infection of the lung has been tr aced from the first recognised case to modern conc epts regarding the va rying ways in which the fungu s can manifest itself.The evidence for the possible aetiologies of the tumour-like form of pulmonary aspergillosis-the aspergilloma -has been presented . This has dem o nstrated the saprophytic nature of the infection with under lying pre -existing lung disease in the vast major ity of cases.T he role of corticosteroids. immunosuppressive drug s a nd anti biotic s is con sidered to be of importance

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“…Diagnosis is also made by isolation ofAspergillus spp. from the sputum, bronchial aspirates, or bronchoalveolar lavage fluid, and a positive precipitin test of anti- Aspergillusfumigatus antibody (3,4). Aspergillus does not usually invade normal lung tissue or other organs except for the wall of the cavity.…”

Section: Discussionmentioning

confidence: 99%

Aspergillus fumigatus Isolated from Blood Samples of a Patient with Pulmonary Aspergilloma after Embolization.

et al. 2000

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Aspergillus DNAwas detected by PCR in the serum sample of a 78-year-old man and galactomannan antigen ofAspergillus by sandwich ELISA was found. However, the infiltrative hyphae were not detected by the histopathologic examination of the lung. He developed hemoptysis, which required embolization of bronchial arteries. Aspergillus fumigatus was isolated from blood samples after embolization by the lysis centrifugation method. To our knowledge, this is probably the first case in which Aspergillus spp. has been isolated from the systemic circulatory blood in a patient with pulmonary aspergilloma after embolization.

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Immunological study of pulmonary aspergilloma

Cited by 12 publications

References 9 publications

Respiratory disease caused by synthetic fibres: a new occupational disease.

Respiratory disease caused by synthetic fibres: a new occupational disease.

Pulmonary Aspergilloma

Aspergillus fumigatus Isolated from Blood Samples of a Patient with Pulmonary Aspergilloma after Embolization.

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