Immunocytochemical localization of mouse placental lactogen in the mouse placenta.

Hall, Jody N.; Talamantes, Frank

doi:10.1177/32.4.6368678

Cited by 51 publications

(23 citation statements)

References 18 publications

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“…This RNA increases to a high level as a percentage of total placental RNA by day 12 and remains elevated until term. The identification of mPL-II mRNA in the fetal (as opposed to the maternal) portion of the placenta is consistent with the immunocytochemical identification of mPL-II in placental giant cells and labyrinth cells (32).…”

Section: Resultssupporting

confidence: 84%

Molecular cloning of mouse placental lactogen cDNA.

Jackson¹,

Colosi²,

Talamantes³

et al. 1986

Proc. Natl. Acad. Sci. U.S.A.

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103

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We have isolated a cDNA clone for the 23-kDa mouse placental lactogen II (mPL-II) from a phage Agtll expression library containing cDNA synthesized from BALB/c placental RNA. Translation in vitro of placental mRNA selected by hybridization to the mPL-ll cDNA clones yields a 26-kDa polypeptide that is the size of the expected precursor protein and that is immunoprecipitated with anti-mPL-II antiserum. The mPL-ll cDNA clones hybridize to a 1.0-kilobase placentalspecific mRNA. This mRNA, found in the fetal portion of the placenta, appears as early as day 10 of gestation and increases to a maximal level by day 12. The mPL-ll cDNA nucleotide sequence has been determined. This sequence contains an open reading frame encoding a polypeptide of 222 amino acids with the amino-terminal 31 amino acids forming the signal sequence for secretion. The predicted secreted protein has 51% amino acid homology with mouse prolactin.

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Section: Resultssupporting

confidence: 84%

Molecular cloning of mouse placental lactogen cDNA.

Jackson¹,

Colosi²,

Talamantes³

et al. 1986

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

103

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“…During the second half of gestation the content of placental lactogen in the chorioallantoic placenta increases progressively (Kelly et al, 1975). The labyrinth zone is responsible for the continued increase in placental lactogen content during gestation ( (Hall & Talamantes, 1984 Alkaline phosphatase is a well established biochemical marker of the chorioallantoic placenta (Padykula, 1959). Our studies indicate that alkaline phosphatase is a particularly good marker for the labyrinth zone of the rat (Table 2).…”

Section: Discussionmentioning

confidence: 99%

“…Trophoblast giant cells are the putative cellular source of placental lactogens (Hall & Talamantes, 1984;Soares et al, 1985). The content of placental lactogen in the entire chorioallantoic placenta of the rat and mouse increases as gestation progresses (Kelly et al, 1975;.…”

Section: Introductionmentioning

confidence: 99%

Developmental changes in the intraplacental distribution of placental lactogen and alkaline phosphatase in the rat

Soares¹

1987

Reproduction

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“…Later in gestation, mPL-II is also synthesized by giant cells within the labyrinth region of the placenta (12), suggesting that additional changes in the patterns of gene expression or of cell differentiation and migration are occurring. For both mPL-I and mPL-II, changes in these hormone mRNA levels correlate closely with hormone protein levels.…”

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confidence: 99%