Immediate psychological distress in quarantined patients with COVID-19 and its association with peripheral inflammation: A mixed-method study

Guo, Qian; Zheng, Yuchen; Shi, Jia; Wang, Jijun; Li, Guanjun; Li, Chunbo; Fromson, John A.; Xu, Yong; Liu, Xiaohua; Xu, Hua; Zhang, Tianhong; Lu, Yao; Chen, Xiaorong; Hu, Hao; Tang, Yingying; Yang, Shuwen; Zhou, Han; Wang, Xiaoliang; Chen, Haiying; Wang, Zhen; Yang, Zongguo

doi:10.1016/j.bbi.2020.05.038

Cited by 344 publications

(398 citation statements)

References 52 publications

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“…The research by Guo et al, 2020 resumes the topic of the highest rates of depression and anxiety among infected patients in relation to the control group. In this light, psychiatric disorders can become more intense, since apathy and anxiety are increasing in individuals with mild cognitive impairment, while agitation and aberrant motor behavior are aggravated in Alzheimer's disease patients ( Beatriz Lara et al, 2020 ).…”

Section: Disorders and Epidemiological Profilesmentioning

confidence: 99%

“…The levels of C-reactive protein, a peripheral inflammatory indicator, correlated positively with patients who showed symptoms of depression. Thus, it is noticed that psychological suffering is something experienced by patients with COVID-19, and that inflammatory markers are related to the levels of depressive characteristics in these patients ( Guo et al, 2020 ).…”

Section: Main Repercussionsmentioning

confidence: 99%

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The psychiatric and neuropsychiatric repercussions associated with severe infections of COVID-19 and other coronaviruses

Moreira

Barbosa

Vieira

et al. 2021

Progress in Neuro-Psychopharmacology and Biological Psychiatry

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Introduction It is known that viral infections are epidemiologically prevalent and some of them are harmful to the central nervous system (CNS) due to the development of neuropsychiatric syndromes which affect the cognitive, affective, behavioral and perceptual domains. Objective To carry out a comprehensive analysis of the psychiatric and neuropsychiatric repercussions of COVID-19 based on epidemiological, pathophysiological and clinical foundations observed in previous and recent pandemic events, and also to make a proposition about effective therapeutic interventions to help tackle this serious public health problem, more specifically in its neuropsychiatric developments. Method This current literature review has utilized literature reserves and scientific search engines MEDLINE, EMBASE and Web of Science. The search terms included, “SARS-CoV-2”, “etiology,” “psychiatric and neuropsychiatric repercussions”, “severe infections” “COVID-19”. Specific choices of unique papers from each of the searches were identified. The inclusion criteria were relevance and availability of full-text. Papers were excluded on the basis of relevance and non-availability of full-text. Papers were identified in the general literature reserve as pertinent to the search terms. Results The main psychiatric and neuropsychiatric repercussions analyzed were depression, anxiety, post-traumatic stress disorder, psychosis, nonspecific neurological symptoms, delirium, cerebrovascular complications, encephalopathies, neuromuscular disorders, anosmia and ageusia. Conclusion The psychiatric and neuropsychiatric symptoms of acute respiratory syndromes can appear during or after the infectious stage. Among the risk factors pointed out for such effects are the female gender, health professionals, presence of avascular necrosis and distressing pain.

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Section: Disorders and Epidemiological Profilesmentioning

confidence: 99%

Section: Main Repercussionsmentioning

confidence: 99%

The psychiatric and neuropsychiatric repercussions associated with severe infections of COVID-19 and other coronaviruses

Moreira

Barbosa

Vieira

et al. 2021

Progress in Neuro-Psychopharmacology and Biological Psychiatry

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“…The worldwide impact of the COVID-19 pandemic is significant and growing with the escalation of global cases, leading to increased mortality and morbidity of patients who survive ( 1 ). As of October 25, 2020, there have been 42,522,402 total cases worldwide with 1,148,490 deaths ( 2 ).…”

Section: Introductionmentioning

confidence: 99%

Cytokine storm induced new onset depression in patients with COVID-19. A new look into the association between depression and cytokines -two case reports

Alpert

Begun

Garren

et al. 2020

Brain, Behavior, & Immunity - Health

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Background Depression appears to be a common complication in patients during and post–COVID-19 infection. Understanding the mechanism of action of cytokines such as interleukin-6, interleukin-10 and others in depression and in cytokine storm syndrome, the core component of COVID- 19, could shine a new light on future treatment options for both disorders. Objective This review demonstrates the role of interleukins in COVID-19 pathogenesis and their role in depression. Results We described cases we have treated as an example for the dual role interleukins have in COVID-19 infection and depression and reviewed approximately 70 articles focusing on the role of interleukins in cytokine storm syndrome and depression. Conclusion This review highlights the key features of cytokines in both diseases. As the scientific community has more time to recover and process the effect of the current pandemic, we believe that additional research will pave the way to diverse pathways to treat depression in these patient and others.

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“…Furthermore, COVID-19 prevention mechanisms, such as lockdowns, self-isolation, and social distancing measures, as well as COVID-19-induced medical resources rationing, have curbed or cut cancer patients' access to traditional healthcare services [42][43][44][45]. As a result, cancer caregivers often have to step up to address patients' healthcare needs and wants [37,[46][47][48][49], which, in turn, could exert substantial mental and physical stress on informal caregivers, above and beyond COVID-19-related burdens the general public shoulders on a daily basis [17][18][19]. Technology-based health solutions can bypass spatial distancing constraints caused by COVID-19 and have the abilities to address unique challenges cancer patients and their caregivers face amid COVID-19 [50][51][52][53].…”

Section: Resultsmentioning

confidence: 99%

Technology-based Health Solutions for Cancer Caregivers to Better Shoulder the Impact of COVID-19: A Systematic Review Protocol

McDonnell

Liang

et al. 2020

Preprint

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Background Cancer patients are particularly vulnerable to COVID-19, partially owing to their compromised immune systems and curbed or cut cancer healthcare services caused by the pandemic. As a result, cancer caregivers may have to shoulder triple crises: the COVID-19 pandemic, pronounced healthcare needs from the patient, and elevated need for care from within. While technology-based health interventions have the potential to address unique challenges cancer caregivers face amid COVID-19, limited insights are available. Thus, to bridge this gap, we aim to identify technology-based interventions designed for cancer caregivers and report the characteristics and effects of these interventions concerning the distinctive challenges cancer caregivers face amid COVID-19. Additionally, this paper will present practical insights into the diverse intervention approaches that can assist in the delivery of digital health solutions for cancer caregivers amid and beyond COVID-19.Methods A systematic review of the literature will be conducted in PubMed, PsycINFO, CINAHL, and Scopus in September, 2020. Articles that center on technology-based interventions for cancer caregivers will be included in the review. The search strategy was developed in consultation with an academic librarian who is experienced in systematic review studies. Titles, abstracts, and full-text articles will be screened against eligibility criteria developed a priori. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses procedures will be followed for the reporting process.Results NA—This is a protocol study.Conclusions COVID-19 has uprooted cancer care as we know it. Due to barriers introduced by the COVID-19 pandemic, such as medical resources rationing, cancer caregivers often have to step up to address patients' healthcare needs and wants. This, in turn, will exert substantial stress on informal caregivers, above and beyond COVID-19-related burdens the general public shoulders on a daily basis. Findings of this study can shed light on evidence-based and practical solutions cancer caregivers can utilize to mitigate the unique challenges they face amid COVID-19. Furthermore, results of this study will also offer valuable insights for researchers who aim to develop interventions for cancer caregivers in the context of COVID-19. In addition, we also expect to be able to identify areas for improvement that need to be addressed in order for health experts to more adequately help cancer caregivers weather the storm of global health crises like COVID-19 and beyond.Study Protocol Registration: PROSPERO CRD42020196301

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Immediate psychological distress in quarantined patients with COVID-19 and its association with peripheral inflammation: A mixed-method study

Cited by 344 publications

References 52 publications

The psychiatric and neuropsychiatric repercussions associated with severe infections of COVID-19 and other coronaviruses

The psychiatric and neuropsychiatric repercussions associated with severe infections of COVID-19 and other coronaviruses

Cytokine storm induced new onset depression in patients with COVID-19. A new look into the association between depression and cytokines -two case reports

Technology-based Health Solutions for Cancer Caregivers to Better Shoulder the Impact of COVID-19: A Systematic Review Protocol

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