Imine-based multicomponent polymerization: Concepts, structural diversity and applications

Catalyst-free synthesis of diverse fluorescent polyoxadiazoles for the facile formation and morphology visualization of microporous films and cell imaging

“…1B). [24][25][26] By rationally designing the monomer structures or combinations, a series of Ugi-type MCPs have been developed for the preparation of polyamides and polypeptoids. [27][28][29][30][31][32][33] However, the product structures of Ugi-type polycondensations are generally limited to diverse polyamide derivatives with linear structures.…”

A Comprehensive Review on Cu‐Catalysed Aerobic Oxidation of Amines to Imines

“…Copper and its complexes are becoming popular as replacement catalysts because they are cheaper and easy to available. They have been widely used for longer time as analytical, anticancer, [26][27][28][29][30][31][32][33] anti-inflammatory, [34,35] polymers [36][37][38][39][40][41][42] and liquid crystalline materials. [43][44][45][46] In industrial [47][48][49][50][51] and commercial synthetic processes, imines actively participate as crucial intermediates in the synthesis of numerous physiologically active N-heterocyclic molecules, [52][53][54] antifungal, antimalarial, antibacterial compounds, etc (Figure 1).…”

Polymeric Copper Chelator for Long-term Inhibition of Breast Cancer Proliferation and Lung Metastasis

“…Multicomponent reactions (MCRs) have been recently employed to investigate new functional polymers. These MCRs include the Ugi, Passerini, Biginelli, Hantzsch, and Kabachnik–Fields (K–F) reactions, as well as alkyne-based and metal-catalyzed MCRs. − We believe that MCRs may overcome the restrictions in developing durable polymeric copper chelators to inhibit cancer metastasis for the following reasons: (1) Certain MCRs effectively generate products with excellent copper-chelating abilities through a one-step reaction. Typical examples are 1,2-dihydropyrimidines by the Biginelli reaction and α-aminophosphonates by the K–F reaction. , Polymers containing these groups can be easily prepared, and these polymers are potential polymer copper chelators.…”