2017
DOI: 10.1371/journal.pone.0180302
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Image quality, diagnostic accuracy, and potential for radiation dose reduction in thoracoabdominal CT, using Sinogram Affirmed Iterative Reconstruction (SAFIRE) technique in a longitudinal study

Abstract: ObjectiveTo step-wise evaluate image quality of sinogram-affirmed iterative reconstruction (SAFIRE) in reduced-dose (RD) thoracoabdominal computed tomography (CT) compared to full-dose (FD) and RD filtered back projection (FBP) in a longitudinal study.Materials and methods122 patients were included in this prospective study. 49 patients (14 men: mean age ± SD, 56±0.4 years; 35 women: 58±1.3 years) completed FD, RD1 (80%-dose) and RD2 (60%-dose) thoracoabdominal CT. Each CT dataset was reconstructed with FBP an… Show more

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Cited by 11 publications
(10 citation statements)
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References 30 publications
(44 reference statements)
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“…L'amp erage est modul e automatiquement par l'appareil (CARE Dose 4D, Siemens) [26]. Les images sont reconstruites par un algorithme it eratif appliqu e aux donn ees brutes (Safire, Siemens) [27][28][29].…”
Section: Appareil Param Etres Et Protocole D'acquisitionunclassified
“…L'amp erage est modul e automatiquement par l'appareil (CARE Dose 4D, Siemens) [26]. Les images sont reconstruites par un algorithme it eratif appliqu e aux donn ees brutes (Safire, Siemens) [27][28][29].…”
Section: Appareil Param Etres Et Protocole D'acquisitionunclassified
“…It can extremely reduce the noises of CT images and has a significant effect on the removal of spiral CTartifacts. is algorithm can be applied in CT image reconstruction to effectively improve the image quality, which can further reduce the radiation dose of CT scans [12]. Moreover, related studies have proved that the improvement of SAFIRE technology can decrease the CTscan dose without increasing the noise of the CT image, and the impact on the image quality is relatively small [13].…”
Section: Introductionmentioning
confidence: 99%
“…3 Thorax MSCT examination has a better level of sensitivity and specificity, but high radiation exposure causes higher cumulative effective radiation dose to patients compared to other examination. 4 High radiation exposure is detrimental to cancer patients undergoing follow-up and increases the level of concern for the harmful effects of radiation doses received by patients and other health professionals. 2,4 For this reason, it is necessary to reduce the radiation dose.…”
Section: Introductionmentioning
confidence: 99%
“…4 High radiation exposure is detrimental to cancer patients undergoing follow-up and increases the level of concern for the harmful effects of radiation doses received by patients and other health professionals. 2,4 For this reason, it is necessary to reduce the radiation dose.…”
Section: Introductionmentioning
confidence: 99%
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