Ileocecal Burkitt's Lymphoma Presenting as Ileocolic Intussusception With Appendiceal Invagination and Acute Appendicitis

Abstract

Intussusception is a common cause of abdominal pain in children. Although most cases are idiopathic, about 10% of cases have a pathologic lead point. Burkitt's lymphoma is not a common etiology. Burkitt's lymphoma might present primarily as intussusception in children but has rarely been associated with appendicitis. We report a case in which a 10-year-old obese boy who initially presented with acute appendicitis due to ileocolic intussusception with appendiceal invagination. He underwent one-trocar laparoscopy and antibiotic treatment. The symptoms recurred 10 days after discharge. Colonoscopy disclosed ileocecal Burkitt's lymphoma as the pathological lead point. This case emphasizes the importance of the age of the patient and the anatomic location of the intussusception related to possible etiology, and hence the most appropriate surgical procedure.

Acute Appendicitis in a Man Undergoing Therapy for Mantle Cell Lymphoma

“…Lymphoma involving an appendectomy specimen has been previously described, albeit rarely [2–15]. We found less than 20 cases of acute appendicitis in association with lymphomatous infiltration in the English literature.…”

“…Carcinomas are the most frequent neoplasms encountered in the appendix; however, other less frequently encountered neoplasms include carcinoid tumors and lymphomas [1]. Lymphoma involving the appendix in association with acute appendicitis has been rarely described previously, with the majority of cases being Burkitt or large B-cell lymphoma [2–15]. Here we report an unusual example of acute appendicitis presenting in a patient undergoing treatment for mantle cell lymphoma.…”

One Month Ongoing Intussusception: Case Report

“…Burkitt's lymphoma originated from B lymphocytes serves very good response to combination chemotherapy. It was rapidly responsive and has prolonged remission [13]. But there are many opposing papers in the literature.…”

Burkitt’s lymphoma masquerading as appendicitis – two case reports and review of the literature

“…This is because the transformation of these cells compromises host defence and evolves mechanisms to escape immune surveillance [12]. Patients with a rapidly growing extranodal intra-abdominal Burkitt's tumour present with symptoms of bowel obstruction, intussusception, or appendicitis [13]. Both cases reported here gave an atypical history for appendicitis especially regarding the duration of the abdominal pain [14].…”