Burkitt’s lymphoma masquerading as appendicitis – two case reports and review of the literature

Weledji, Elroy Patrick; Ngowe, Marcelin Ngowe; Abba, John S

doi:10.1186/1477-7819-12-187

Cited by 16 publications

(10 citation statements)

References 16 publications

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“…A short-coming of the surgical practice in resource-limited and endemic areas is that appendicectomy specimens are rarely sent for histological examination. Being an extranodal lymphoid organ it could be the only initial indication of a lymphoma or an underlying pathology [20] . CMV has also been isolated from appendix specimens raising the possibility that CMV may be causative or a co-factor [11,15,24,25] .…”

Section: Abdominal Pain In Hiv/aidsmentioning

confidence: 99%

Gastrointestinal surgery and the acquired immune deficiency syndrome

Weledji

Nsagha

Chichom

et al. 2015

Annals of Medicine &Amp; Surgery

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Acquired immune-deficiency syndrome (AIDS) is becoming an increasing problem to the surgeon. The impact of HIV/AIDS on surgical practice include the undoubted risk to which the surgeon will expose him or herself, the atypical conditions that may be encountered and the outcome and long term benefit of the surgical treatment in view of disease progression. The two factors most associated with surgical outcome and poor wound healing were AIDS and poor performance status (ASA score). This article questions whether gastrointestinal surgical procedures can be safe and effective therapeutic measures in HIV/AIDS patients and if surgical outcome is worthy of the surgeon's ethical responsibility to treat. As HIV/AIDS patients are not a homogeneous group, with careful patient selection, emergency laparotomy for peritonitis confers worthwhile palliation. However, aggressive surgical intervention must be undertaken with caution and adequate peri-operative care is required. Symptomatic improvement of anorectal pathology may make delayed wound healing an acceptable complication. Alternatives to surgery can be contemplated for diagnosis, prophylaxis or palliation.

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Section: Abdominal Pain In Hiv/aidsmentioning

confidence: 99%

Gastrointestinal surgery and the acquired immune deficiency syndrome

Weledji

Nsagha

Chichom

et al. 2015

Annals of Medicine &Amp; Surgery

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“…Being an extranodal lymphoid organ appendicitis could be the only initial indication of a lymphoma or lymphadenopathy from Myocobacterium avium-intracellulare obstructing the appendiceal ostium. Thus appendi-cectomy specimens should routinely be examined histologically [32]. With careful patient selection, emergency laparotomy confers worthwhile palliation [30,31,33].…”

Section: The Aids Patientmentioning

confidence: 99%

The Dilemma of Acute Appendicitis

Weledji¹

2016

Actual Problems of Emergency Abdominal Surgery

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Acute appendicitis is one of a relatively dwindling number of conditions in which a decision to operate may be based solely on clinical findings. Regular re-assessment of patients and making use of the investigative options available will meet the standard of care expected by patients with acute abdominal pain. In this article, the greater importance of history and examination over investigations in the early diagnosis of acute appendicitis is emphasized. The ability to identify the presence of peritoneal inflammation probably has the greatest influence on the final surgical decision.

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“… 7 Ileo-caecal Burkitt’s lymphoma which is usually of the sporadic type may masquerade as appendicitis. Thus, the importance of routine examination of appendectomy specimens, especially in high-risk areas where also the immunodeficiency-associated type has an intestinal preponderance, 39 should be considered. The endemic Burkitt’s lymphoma type of the tropics where chronic malaria reduces the resistance to the causative EBV, mostly present as jaw tumors in children.…”

Section: Emergency Surgerymentioning

confidence: 99%

“…44 , 45 Appendectomy and colectomy are the commonest abdominal operations in AIDS patients. 39 Being an extranodal lymphoid organ it could be the only initial indication of a lymphoma or an underlying pathology although citomegalovirus (CMV) has also been isolated from appendix specimens raising the possibility that CMV may be causative or a co-factor. 44 , 46 It is crucial to have close liaison between AIDS physicians and AIDS surgeons to exclude pre-terminal cases and keep down negative laparotomies to acceptable rate.…”

Section: Impact Of Hiv/aids On Surgery For Non-hodgkin’s Lymphomamentioning

confidence: 99%

Surgery for non-Hodgkin’s lymphoma

Weledji

Orock

2015

Oncol Rev

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Non-Hodgkin lymphomas (NHLs) are a diverse group of blood cancers derived from lymphocytes that vary significantly in their severity. Surgery is not often used as a treatment because of the efficacy of chemotherapy, biological therapy, radiotherapy and hematopoietic stem cell transplantation. We reviewed the natural history and possible role of surgery for NHL. Surgery may be useful in confirming or refuting an equivocal radiological diagnosis through biopsy, removing symptomatic limited disease from an affected organ and in splenectomy for primary splenic lymphoma. Emergency abdominal surgery for acute complications of NHL provides palliation and diagnosis. There is as yet no consensus as to the optimum treatment for symptomatic limited disease affecting an organ and timing of chemotherapy perioperatively. Prospective randomized trials are required.

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Burkitt’s lymphoma masquerading as appendicitis – two case reports and review of the literature

Cited by 16 publications

References 16 publications

Gastrointestinal surgery and the acquired immune deficiency syndrome

Gastrointestinal surgery and the acquired immune deficiency syndrome

The Dilemma of Acute Appendicitis

Surgery for non-Hodgkin’s lymphoma

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