“…Although most patients with AD have high concentrations of total and allergen‐specific serum IgE levels and positive skin prick and intracutaneous test reactions of the immediate type to common environmental allergens, a subgroup of AD patients, both children and adults, suffer from a skin disease with features that clinically resemble the skin lesions and distribution pattern of AD, but that is not associated with sensitization to aero‐ or food allergens (3, 4, 7, 10–12). As the main clinical characteristic, these patients suffer from a “pure” type of AD, without previous or actual associated respiratory diseases (7, 11, 12).…”