<i>Stachytarpheta jamaicensis</i> (L.) Vahl: From Traditional Usage to Pharmacological Evidence

Liew, Pearl Majorie; Yong, Yoke Keong

doi:10.1155/2016/7842340

Cited by 27 publications

(31 citation statements)

References 31 publications

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“…Carbohydrates, alkaloids, saponins, phenolic compounds, and flavonoids were present in the powdered sample. The presence of these phytochemicals agrees with the earlier report of Liew and Yong, 19 who identified additional phytochemicals like terpenoids, steroids, proteins and glycosides in the leaves of S. jamaicensis. Figure 1 represents the percentage free radical scavenging activity of the methanol and ethyl acetate extracts of S. jamaicensis leaves.…”

Section: Phytochemical Constituents Of Stachytarpheta Jamaicensis Leavessupporting

confidence: 91%

Evaluation of the Antioxidant and Hypoglycaemic Potentials of the Leaf Extracts of Stachytarphyta jamaicensis (Verbenaceae)

Egharevba¹,

Chukwuemeke-Nwani²,

Eboh³

et al. 2019

TJNPR

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Stachytarpheta jamaicensis (family Verbanaceae) commonly known as blue porterweed is widely used in folk medicine for the treatment of various diseases including diabetes mellitus. The present study investigated the blood glucose lowering effect and the antioxidant activity of the leaf extracts of Stachytarpheta jamaicensis. The phytochemical screening of the powdered leaf sample was done according to standard procedures. The antioxidant activity of the methanol and ethyl acetate extracts of the leaves were investigated using the 1,1-diphenyl-2-picrylhydrazine (DPPH) radical scavenging assay, the total phenolic and flavonoid contents were also evaluated following standard procedures. The hypoglycaemic effect of the extracts was evaluated using streptozotocin-induced diabetes in rats. Phytochemical screening shows the presence of carbohydrates, alkaloids, saponins, tannins, phenolic compounds, and flavonoids. The extracts demonstrated appreciable and concentration-dependent radical scavenging effect with IC50 values of 16.95 µg/mL and 33.12 µg/mL, for the methanol extract and ethyl acetate extract, respectively. Oral administration of the extracts at 200 mg/kg and 400 mg/kg daily dose significant lowers blood glucose levels in streptozotocin-induced diabetes in experimental rats compared to the control group (untreated diabetic animals). The present findings have therefore shown that S. jamaicensis leaves has hypoglycaemic and antioxidant effects and may therefore serve as a potential source of hypoglycaemic agent as well as antioxidant agents for the prevention and management of free radical induced metabolic diseases.

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Section: Phytochemical Constituents Of Stachytarpheta Jamaicensis Leavessupporting

confidence: 91%

Evaluation of the Antioxidant and Hypoglycaemic Potentials of the Leaf Extracts of Stachytarphyta jamaicensis (Verbenaceae)

Egharevba¹,

Chukwuemeke-Nwani²,

Eboh³

et al. 2019

TJNPR

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“…S. jamaicensis has been reported to contain secondary metabolites alkaloids, flavonoids, phenols, steroids, and terpenoids; and has traditionally been used for medicinal purpose in various countries (Putera and Shazura 2010). The active compounds have pharmacological effects as antacid, analgesic, anti-inflammatory, hypotensive, antihelminthic, diuretic, laxative, lactagogue, purgative, sedative, spasmogenic, vasodilator, vulnerary, and vermifuge properties (Liew and Yong 2016). Our study showed that the polyisoprenoid of S. jamaicensis had moderate inhibitory effects on the growth of E. coli and S. aureus.…”

Section: Resultsmentioning

confidence: 61%

Antimicrobial activity of polyisoprenoids of sixteen mangrove species from North Sumatra, Indonesia

Sumardi¹,

Basyuni

Wati

2018

Biodiversitas

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Sumardi, Basyuni M, Wati R. 2018. Antimicrobial activity of polyisoprenoids of sixteen mangrove species from North Sumatra, Indonesia. Biodiversitas 19: 1243-1248. Mangroves including those that are distributed in the coast of North Sumatra containpolyisoprenoid with varying levels of polyprenol and dolichol constituents. Differences in polyisoprenoid levels were closely related tothe salinity of sea but the information about their biological activities is scarce. The present study aimed to describe the biologicalactivities, antimicrobial, antioxidant, and antifungal effects of polyisoprenoid extracts from sixteen mangrove species of North Sumatra,Indonesia. Polyisoprenoids were isolated from mangrove leaves and tested for their antimicrobial activity against Escherichia coli,Staphylococcus aureus, and Candida albicans. Meanwhile, their antioxidant activity was represented by their capacity in scavengingDPPH (2,2-diphenyl-1-picrylhydrazyl) free-radical agents. The most predominant polyisoprenoids found in sixteen mangrove leafextracts was dolichols (75%). Polyprenols-dominant species, Acacia auriculiformis, Hibiscus tiliaceus, Pongamia pinnata, and Ricinuscommunis, and dolichols-dominant species, Avicennia lanata, Av. marina, Av. officinalis, Barringtonia asiatica, Bruguieragymnorrhiza, Calophyllum inophyllum, Nypa fruticans, and Pandanus odoratissimus, inhibited the growth of E. coli and S. aureus.However, the antioxidant activity of those sixteen mangrove species was of a weak category. Surprisingly, all other mangrovespolyisoprenoid extracts did not inhibit C. albicans growth. This study suggested that polyisoprenoids in mangroves have potentialantibacterial properties to be developed further.

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“…Plant-derived medicines have been part of traditional healthcare in most parts of the world for thousands of years. As such, there is increasing interest in ethnobotany for the subsequent isolation and identification of novel therapeutic agents to help stem the high prevalence of hospital-acquired and community-acquired bacterial infections (Chariandy et al 1999;Palombo and Semple 2001;Liew and Yong 2016). Further, given the increasing incidence of antibiotic resistance (Monroe and Polk 2003), there is a continual need for new and effective bactericidal agents (Palombo and Semple 2001).…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Antimicrobial and anti-inflammatory activities of australian native plants in the context of wound healing: A review

Manirujjaman

Collet

2020

Biologia

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Wound healing is an essential biological process which involves tissue repair and recovery and includes the action of a complex system of blood cells, cytokines, and growth factors. It is a process attended by integrated cellular and biochemical events and characterized by four phases: haemostasis, inflammation, proliferation, and remodelling. Medicinal plants which have healing applications, continue to play a central role in the healthcare system of a large proportion of the world's population. Numerous studies have shown that several Australian plant species used medicinally, contain biologically active extracts and compounds which have enormous potential for the treatment and management of a wound. Medicinal plants contain a wide range of chemical compounds as the unique flora of Australia offers an array of diverse bioactives, which elicit antibacterial, antioxidant, antiinflammatory and wound healing abilities. Such properties are not limited to the edible sections of plants as the roots, bark, sap, leaves and seeds from a vast array of plants have demonstrated similar effects. In this review article, various Australian native plants which are scientifically proven to have antibacterial and anti-inflammatory properties that support wound healing, are discussed. This review also briefly discusses the general wound healing process, wound-colonizing bacteria, factors that affect wound healing, and costs involved in the treatment and management of chronic wounds.

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Stachytarpheta jamaicensis (L.) Vahl: From Traditional Usage to Pharmacological Evidence

Cited by 27 publications

References 31 publications

Evaluation of the Antioxidant and Hypoglycaemic Potentials of the Leaf Extracts of Stachytarphyta jamaicensis (Verbenaceae)

Evaluation of the Antioxidant and Hypoglycaemic Potentials of the Leaf Extracts of Stachytarphyta jamaicensis (Verbenaceae)

Antimicrobial activity of polyisoprenoids of sixteen mangrove species from North Sumatra, Indonesia

Antimicrobial and anti-inflammatory activities of australian native plants in the context of wound healing: A review

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