A new and efficient method for the synthesis of a variety of N-substituted pyrroles from condensation reactions of 2,5-hexanedione with amines or diamines using ZrOCl 2 ·8H 2 O as a water-tolerant Lewis acid catalyst at room temperature is described.The use of nontoxic, inexpensive, easily available and reusable catalyst under solvent-free conditions make this protocol practical, environmentally friendly and economically attractive.