ChemInform Abstract: N‐Substituted Pyrrole Synthesis by Paal—Knorr Condensation Using Recyclable Cationic Exchange Resin in Water.

Abstract

A simple and effective Paal-Knorr condensation catalyzed by a reusable cationic exchange resin is reported. The reaction is temperature-sensitive: at 100 °C formation of the corresponding furan from an intramolecular condensation dominates and above 140 °C the resin decomposes. At 130 °C the reaction exclusively provides the targeted pyrroles. -(HE, Y.-H.; WANG, G.-Q.; GUAN*