<i>Mimosa pudica</i>
            floral nanoparticles: a potent antibiotic resistance breaker

Ranjani, S; Begum, Irshad; Santhoshini, J; Kumar, Nachimuthu Senthil; Ruckmani, K.; Hemalatha, S.

doi:10.1080/24701556.2020.1852429

Cited by 14 publications

(4 citation statements)

References 38 publications

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“…The plates were then incubated at 37ºC for overnight. The minimal concentration of MBNc which completely kills organisms were recorded as bactericidal concentration [24][25][26][27][28].…”

Section: Bactericidal Assaymentioning

confidence: 99%

“…1b). Myrobalans extract is reported to have phytocompounds, polymers of carbohydrates, polysaccharides, polyphenols, enzymes, coenzymes and other proteins which act as a bioreductant in reducing the silver ions [24][25][26][27].…”

Section: Biogenesis Of Myrobalans Mediated Green Nano Colloids (Mbnc) and Physicochemical Characterizationmentioning

confidence: 99%

“…EDAX integrated FESEM depicts the elemental composition of nanocolloidal particles[24][25][26]. HRTEM measurement was carried out by placing the drop of MBNc on copper grids and incubated under desiccation.…”

mentioning

confidence: 99%

“…HRTEM measurement was carried out by placing the drop of MBNc on copper grids and incubated under desiccation. The grid was loaded on the sample holder and HRTEM was taken using HRTEM: Jeol/JEM 2100 of 200kV under LaB6 Electron gun with 0.23nm resolution and lattice resolution 0.14 nm integrated with SAED[24][25][26].2.4 Antimicrobial property of biologically synthesized green nanocolloids (MBNc) against marine pathogensThe antimicrobial potential of MBNc was validated through four different assays namely, bacteriostatic assay (Minimum inhibitory concentration), time kill curve validating through different concentrations of MBNc, and Bactericidal assay (Minimum bactericidal concentration) and antibio lm assay.…”

mentioning

confidence: 99%

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Myrobalans Mediated Nanocolloids in Controlling Marine Pathogens

Ranjani

Parthasarathy

Rameshkumar

et al. 2021

Preprint

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Aquaculture production is affected by disease outbreak, which affect the production, profitability, and sustainability of the global aquaculture industry. Antibiotics have been widely used to control various pathogens. Due to its uncontrollable and indiscriminate usage, pathogens have developed resistance towards antibiotics. This current study aims to synthesize green silver- of silver nanocolloids (MBNc) from the extract of three myrobalans. MBNc was characterized by using UV-Vis spectroscopy, DLS, Zeta potential, FE-SEM. EDX, HRTEM, and SAED techniques. The array of antimicrobial assays were performed to evaluate the efficacy of MBNc against vibriosis causing pathogens including V. harveyi, V. alginolyticus, V. parahaemolyticus, and foodborne pathogen S. haemolyticus, isolated from infected fish. Further, the presence of ESBL genes including CTX-M-15 and Amp C were analyzed in control and MBNc treated strains. From our studies, it was observed that MBNc was very effective in controlling the growth and biofilm formation in all tested marine pathogens and effectively abolish the genes encoding ESBL CTX-M-15 in antibiotic-resistant pathogens tested. Thus, MBNc can be formulated to control the growth of marine pathogens and it can be used as an alternative to antibiotics to prevent infection in cage culturing and aquafarming.

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“…The plates were then incubated at 37ºC for overnight. The minimal concentration of MBNc which completely kills organisms were recorded as bactericidal concentration [24][25][26][27][28].…”

Section: Bactericidal Assaymentioning

confidence: 99%

Section: Biogenesis Of Myrobalans Mediated Green Nano Colloids (Mbnc) and Physicochemical Characterizationmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Myrobalans Mediated Nanocolloids in Controlling Marine Pathogens

Ranjani

Parthasarathy

Rameshkumar

et al. 2021

Preprint

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Citrus limon phytocompounds decorated nanoparticles control poultry pathogens

2023

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Silver Decorated Myconanoparticles Control Growth and Biofilm Formation in Uropathogenic E. coli

Ranjani

Kathun

Hemalatha

2021

Appl Biochem Biotechnol

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Nanotechnology involves the synthesis of nanoparticles that has been used in therapeutic application for treating diseases. In this present study we have adopted the synthesis of myconanoparticles from the extracellular extract of endophytic fungi Penicillium sclerotiorum (PsNps) and validated for its antibacterial potential against antibiotic resistant uropathogenic E. coli and ATCC (25922) strain of E. coli. Endophytic fungi were isolated from the healthy leaves of Tamarindus indica. The genomic DNA from endophytic fungi was isolated and ITS region was ampli ed by polymerase chain reaction (PCR) using universal fungal primers ITS1 and ITS4and sequenced for the identi cation of endophytic fungal isolates. Penicillium sclerotiorum extract were used for the synthesis silver nanoparticles (PsNps) and were characterized by UV-Vis spectroscopy, Fourier transform-infrared spectroscopy (FTIR), Zeta potential, FE-SEM and Energy-Dispersive X-ray analysis (EDAX). Antibacterial activity of PsNps was tested against the antibiotic resistant uropathogenic E. coli and ATCC (25922) strain of E. coli. Further experiments were carried out to explore the potential of PsNps in regulating the CTX-M-15 gene. The antimicrobial activity showed that the PsNps inhibited growth, bio lm formation in both the strains of E. coli. The expression of gene encoding CTX-M-15 was down regulated in resistant strain of uropathogenic E. coli. Our results suggest that the PsNps could be used as an alternative source for the antibiotics. Thus, further studies can be conducted to prove the in vivo potential of PsNps and can be formulated for commercialization.

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Mimosa pudica floral nanoparticles: a potent antibiotic resistance breaker

Cited by 14 publications

References 38 publications

Myrobalans Mediated Nanocolloids in Controlling Marine Pathogens

Myrobalans Mediated Nanocolloids in Controlling Marine Pathogens

Citrus limon phytocompounds decorated nanoparticles control poultry pathogens

Silver Decorated Myconanoparticles Control Growth and Biofilm Formation in Uropathogenic E. coli

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