DISCUSSIONThe first description of Hemophilus paraphrophilus was given by Zinneman et al. It was described as a fastidious, catalase-negative, oxidase -positive, V-factor dependant, gram negative cocco-bacillus that needed a carbon dioxide enriched atmosphere for supporting its growth [4]. A recent reclassification has placed these organisms in a new genus of Aggregatibacter, as they are independent of factor X and variably dependent on factor V for their growth in vitro [5].This organism is a normal commensal inhabiting the oro-pharynx, nasopharynx and lower gastrointestinal tract [6]. Human diseases microbiology Section
ABSTRACTAggregatibacter paraphrophilus (former name, Haemophilus paraphrophilus) is a normal inhabitant of the naso-and oropharynx and has been rarely reported as a cause of human infections. A case of infective endocarditis by this organism is being reported and literature of endocarditis cases caused by Aggregatibacter paraphrophilus is being reviewed.