[1] It has recently been found that solar wind dynamic pressure changes can dramatically affect the precipitation of magnetospheric particles on the high-latitude ionosphere. We have examined the effect of large solar wind dynamic pressure increases on the location, size, and intensity of the auroral oval using particle precipitation data from Defense Meteorological Satellite Program (DMSP) spacecraft. Three events have been selected for study during the time period after 1997 when four DMSP spacecraft (F11-F14) were simultaneously operational. Interplanetary magnetic field (IMF) orientation is different from event to event. For each event, we determine equatorward and poleward boundaries of the auroral oval before and after an increase in solar wind pressure. Also, using measured integral fluxes, we construct precipitating particle energy input maps for the auroral oval. All cases studied show a significant change of the auroral oval location, size, and intensity in response to the solar wind pressure pulse. Most prominent are an increase of the auroral zone width and a decrease of the polar cap size when the solar wind dynamic pressure increases under steady southward IMF conditions. An increase in total precipitating particle energy flux is also observed. A smaller response is seen when the IMF B z has a simultaneous northward turning and when it is nearly zero before the pressure enhancement. Our results also point to significant differences between the auroral precipitation response to solar wind pressure changes and its response to isolated substorms, the former inducing a global auroral reaction while the latter is related to more localized premidnight disturbances. Auroral UV observations from the Polar spacecraft during our events are found to give results consistent with the results we get from the precipitating particle observations.

A prospective, observational study of 110 patients with serious infections due to Enterococcus spp. in 6 university and community teaching hospitals in Connecticut was conducted to define the epidemiology of community and nosocomial serious enterococcal infections and to determine risk factors, including antibiotic resistances, that contribute to outcome. Serious community and nosocomial enterococcal infections involved a variety of sites, and antibiotic resistance was common. Types of infection by major organ system were cardiovascular, 54% (catheter-related bacteremia 28%, primary bacteremia 18%, endocarditis 6%, septic thrombophlebitis 1%); intra-abdominal, 13% (including cholangitis, 6%); renal, 13%; skin and soft tissue, 5%; bone and joint, 4%; pleuropulmonary, 4%; central nervous system, 3%; deep surgical wound, 3%; and endometritis, 2%. Sixty-one percent of infections were nosocomial; 48% of these occurred in the intensive care unit. Enterococcus faecium was responsible for 20% of all infections. Antibiotic resistances among the infections included high-level gentamicin resistance (26%), ampicillin resistance (10%), and vancomycin resistance (8%). Clinical cure was achieved in 64% of patients; 6.8% of patients relapsed, 6.8% had recurrence of the infection with a different pathogen, and overall mortality was 23%. Ampicillin resistance and a high acute physiology and chronic health evaluation (APACHE) II score were highly predictive of lack of cure.