Elsholtzia blandaBenth: New Citral-rich Chemotypes from India

The antimicrobial activity and chemical composition of Elsholtzia blanda (Benth.) Benth. essential oils in Lam Dong Province, Viet Nam

“…This species has been used as traditional medicine by local people in their daily life. The chemical constituents of E. blanda and compositional variations in the essential oils of this species also have been reported in previous studies (Fang & Lin, 1990;Bestmann et al, 1992;Thappa et al, 1999;Ping et al, 2002;Lesueur et al, 2007;Rana et al, 2012;Kotoky et al, 2017), and indicating geranial acetate, 1,8-cineole, citral, and linalool are dominant components. However, significant variation in the essential oil content and its associated chemical components with time and geographical variation was also reported (Cheng et al, 1989;Lesueur et al, 2007;Saei-Dehkordi et al, 2010).…”

“…The sesquiterpene composed 25.81%, while the monoterpene made up 74.19%, of which the monoterpene hydrocarbons had the most important contribution (56.52%). and linalool (57.9%), geranial (43.5%) were found to be major components in the essential oil of this species distributed in China and India respectively (Fang et al, 1990;Bestmann et al, 1992;Ping et al, 2002;Rana et al, 2012;Kotoky et al, 2017). In addition, comparing the main compounds of essential oil of E. blanda growing in Son La, and Lao Cai Province of Viet Nam is 1,8-cineole (20.8%) and linalool (75.2%) (Lesueur et al, 2007).…”

GC-MS combined with multivariate analysis for the determination of the geographical origin of Elsholtzia rugulosa Hemsl. in Yunnan province

“…Among them, Elsholtzia ketone, linalool, artemisyl ketone, humulenol, isospathulenol, andrographolide, and many chemical components isolated from E. rugulosa have bio-medical activities such as anti-cancer, anti-inflammatory, anti-oxidation, anti-malarial, and anti-influenza virus. 5–18 These compounds are also the material basis of the medicinal effect of E. rugulosa . It can be seen from Table 1 that under the significance level P < 0.05, the differential volatile components of E. rugulosa in the four origins reach more than 50, indicating that the origin has a great influence on the volatile components of E. rugulosa .…”

“…Among them, Elsholtzia ketone, linalool, artemisyl ketone, humulenol, isospathulenol, andrographolide, and many chemical components isolated from E. rugulosa have biomedical activities such as anti-cancer, anti-inammatory, antioxidation, anti-malarial, and anti-inuenza virus. [5][6][7][8][9][10][11][12][13][14][15][16][17][18] These compounds are also the material basis of the medicinal effect of E. rugulosa. It can be seen from Table 1 that under the signicance level P < 0.05, the differential volatile components of E. rugulosa in the four origins reach more than 50, indicating that the origin has a great inuence on the volatile components of E. Under the high signicance of difference level (F > 50, P < 0.05), the E. rugulosa pharmaceutical components with the highest relative content of the four origins were Elsholtzia ketone in Fumin, (1R,7S,E)-7-isopropyl-4,10dimethylenecyclodec-5-enol in Dali, squalene in Lijiang, and these compounds can be labeled as origin characteristic medicinal components.…”

“…[4][5][6][7][8][9][10] In addition to the abovementioned medicinal functions, recent studies have shown that many compounds isolated from E. rugulosa have anticancer and even relieve Alzheimer's symptoms. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Through phytochemical methods, a variety of terpenoids, polyphenols, avonoids, and other non-volatile components were identied, such as anti-inammatory triterpene ursolic acid, 16,18 antioxidant polyphenol rosmarinic acid, 26 anti-inuenza and anti-Alzheimer's avonoid Luteolin, 11,12 etc. In the essential oil of E. rugulosa, b-dehydroelsholtzia ketone and Elsholtzia ketone were identied.…”