Dipteryx alataVogel May Improve Lipid Profile and Atherogenic Indices in Wistar RatsDipteryx alataand Atherogenic Indices

Abstract

Worldwide prevalence of noncommunicable chronic degenerative diseases is among the main causes of death worldwide. The consumption of some foods such as nuts and seeds may be beneficial in preventing these diseases. Dipteryx alata Vogel (DA), known popularly as Baru, belongs to the family Fabaceae and is a native fruit tree from the Brazilian savanna. The purpose of this study was to evaluate the use of seeds of DA on the metabolic and oxidative profile of Wistar rats. Animals were divided randomly into four groups (n = 10): G1 (control group), and G2 (treated with DA 20%), G3 (treated with DA 30%), and G4 (treated with DA 40%). After 40 days, animals were euthanized and metabolic and oxidative profiles were analyzed (glycemia, cholesterol, triglycerides [TGs], high-density lipoprotein-cholesterol [HDL-c], very low-density lipoprotein-cholesterol [VLDL-c], low-density lipoprotein-cholesterol [LDL-c], C reactive protein, aspartate aminotransferase, alanine aminotransferase, Lee index, weight, visceral fat, ferric reducing ability of plasma, and ferric-xylenol orange method. The use of the seeds was effective in reducing TGs, VLDL-c, LDL-c, and increasing HDL-c but did not interfere in the percentage of weight gain, visceral fat, levels of total cholesterol, and oxidative stress. Based on our results, it is possible to say that the use of DA may improve the lipid profile of Wistar rats and we may suggest that the consumption of DA almonds or products prepared with them may be an effective option for the intake of healthy products.

Hydrocolloids and partially defatted cake on encapsulation of baru oil (Dipteryx alata Vogel): a study on emulsion, particle, and oxidative stability

“…Several studies have shown antioxidant activity of the baru almond (and consequently of its oil) against oxidative stress, cardiovascular diseases risk, cancer, atherogenic indices, gastrointestinal diseases, abdominal adiposity, and wound healing. In addition, it helps to improve the lipid pro le in overweight individuals (Bailão et al, 2015;Bento et al, 2014;Coco et al, 2021;de Souza et al, 2018;Fetzer et al, 2018;Ragassi Fiorini et al, 2017). Furthermore, the increase in Cerrado deforestation and therefore the extinction of its species has been discussed.…”

Therapeutic Potential of Brazilian Cerrado Campomanesia Species on Metabolic Dysfunctions

“…These plants include graviola ( Annona muricata Linnaeus), which has displayed anti-ulcerogenic effects [ 24 ], bocaiuva ( Acrocomia aculeata ) which has presented anti-diabetic properties [ 25 ] and anti-inflammatory and diuretic actions [ 26 ], and baru ( Dipteryxalata Vog. ), which was observed to cause improvement in lipid profiles and atherogenic indexes [ 27 ]. Another important plant from the Brazilian Cerrado is pequi ( Caryocar brasiliense ) which has displayed anti-inflammatory and antioxidant properties, decreasing hepatic damage induced by carbon tetrachloride in rats [ 28 ].…”

APLICAÇÕES TERAPÊUTICAS DA ESPÉCIE Dipteryx alata Vogel

“…Por não haver aumento nos níveis de AST (aspartato aminotransferase) e ALT (alanina aminotransferase) os autores acreditam que não houve danos em células do fígado indicando que a amêndoa é segura para consumo. Em resumo a utilização de amêndoa na alimentação pode auxiliar na prevenção de doenças cardiovasculares porque houve redução significativa de razão de risco cardíaco, no coeficiente e índice aterogênico (FIORINI et al, 2017).…”