2020
DOI: 10.1111/jdv.16461
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Demodex: a skin resident in man and his best friend

Abstract: Demodex mites are microscopic arachnids found in the normal skin of many mammals. In humans, it is well established that Demodex mite density is higher in patients with the skin condition rosacea, and treatment with acaricidal agents is effective in resolving symptoms. However, pathophysiology of rosacea is complex and multifactorial. In dogs, demodicosis is a significant veterinary issue, particularly the generalized form of the disease which can be fatal if untreated. In each species, clinical and molecular … Show more

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Cited by 39 publications
(29 citation statements)
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References 89 publications
(126 reference statements)
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“…Humans are born without Demodex mites on the skin [43,54], and the mites are progressively acquired by direct contact with the skin of other humans [44,55]. As a commensal, the Demodex mite likely controls the immune system of the host, through undefined mechanisms, to ensure its own survival [8,10,[56][57][58][59][60].…”
Section: Demodex and Demodicosismentioning
confidence: 99%
“…Humans are born without Demodex mites on the skin [43,54], and the mites are progressively acquired by direct contact with the skin of other humans [44,55]. As a commensal, the Demodex mite likely controls the immune system of the host, through undefined mechanisms, to ensure its own survival [8,10,[56][57][58][59][60].…”
Section: Demodex and Demodicosismentioning
confidence: 99%
“…The average incidence rate of mite infection is 13–70% worldwide ( 2 4 ). Moreover, demodex has been reported in the eyelashes of 18% of healthy individuals aged 21–35 years ( 5 7 ). Demodex blepharitis is a chronic inflammatory disease caused by demodex infestation, affecting the lid margin and ocular surface, which can lead to serious eye problems ( 1 ).…”
Section: Introductionmentioning
confidence: 99%
“…Los ácaros de Demodex sp., de la familia Demodicidae, suborden trombidiformes, orden acariformes, son ácaros minúsculos, descritos por primera vez por Henle y Berger en 1841, 1 se consideran microorganismos comensales de la microfauna normal de la piel de los mamíferos, donde residen de forma permanente dentro o fuera del folículo piloso y glándulas sebáceas. Los Demodex folliculorum y Demodex brevis se consideran propios de los humanos y la Demodecidosis se ha reportado como una infección de la piel humana causada por estos ectoparásitos que han sido relacionados con diversas condiciones clínicas, en donde la unidad pilosebácea está afectada como en rosácea, dermatitis seborreica, Pitiriasis folliculorum, foliculitis y blefaritis.…”
Section: Introductionunclassified
“…Los Demodex folliculorum y Demodex brevis se consideran propios de los humanos y la Demodecidosis se ha reportado como una infección de la piel humana causada por estos ectoparásitos que han sido relacionados con diversas condiciones clínicas, en donde la unidad pilosebácea está afectada como en rosácea, dermatitis seborreica, Pitiriasis folliculorum, foliculitis y blefaritis. 1,2 El mecanismo de transmisión es por el contacto piel con piel, por lo que resulta importante en esta pandemia debido al hacinamiento y el contacto estrecho y prolongado entre las personas.…”
Section: Introductionunclassified
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