Taking advantage of the large number of seismic stations installed in Europe, in particular in the greater Alpine region with the AlpArray experiment, we derive a new high-resolution 3-D shear wave velocity model of the European crust and uppermost mantle from ambientnoise tomography. The correlation of up to 4 yr of continuous vertical-component seismic recordings from 1293 broad-band stations (10 • W-35 • E, 30 • N-75 • N) provides Rayleigh wave group velocity dispersion data in the period band 5-150 s at more than 0.8 million virtual source-receiver pairs. 2-D Rayleigh wave group velocity maps are estimated using adaptive parametrization to accommodate the strong heterogeneity of path coverage. A probabilistic 3-D shear wave velocity model, including probability densities for the depth of layer boundaries and S-wave velocity values, is obtained by nonlinear Bayesian inversion. A weighted average of the probabilistic model is then used as starting model for the linear inversion step, providing the final V s model. The resulting S-wave velocity model and Moho depth are validated by comparison with previous geophysical studies. Although surface wave tomography is weakly sensitive to layer boundaries, vertical cross-sections through our V s model and the associated probability of the presence of interfaces display striking similarities with reference controlledsource seismology (CSS) and receiver function sections across the Alpine belt. Our model even provides new structural information such as an ∼8 km Moho jump along the CSS ECORS-CROP profile that was not imaged by the reflection data due to poor penetration across a heterogeneous upper crust. Our probabilistic and final shear wave velocity models have the potential to become new reference models of the European crust, both for crustal structure probing and geophysical studies including waveform modelling or full-waveform inversion.

The dynamics of continental subduction is largely controlled by the rheological properties of rocks involved along the subduction channel. Serpentinites have low viscosity at geological strain rates. However, compelling geophysical evidence of a serpentinite channel during continental subduction is still lacking. Here we show that anomalously low shear-wave seismic velocities are found beneath the Western Alps, along the plate interface between the European slab and the overlying Adriatic mantle. We propose that these seismic velocities indicate the stacked remnants of a weak fossilised serpentinite channel, which includes both slivers of abyssal serpentinite formed at the ocean floor and mantle-wedge serpentinite formed by fluid release from the subducting slab. Our results suggest that this serpentinized plate interface may have favoured the subduction of continental crust into the upper mantle and the formation/exhumation of ultra-high pressure metamorphic rocks, providing new constraints to develop the conceptual and quantitative understanding of continentalsubduction dynamics.

SUMMARY We have constructed a 3-D shear wave velocity (Vs) model for the crust and uppermost mantle beneath the Middle East using Rayleigh wave records obtained from ambient-noise cross-correlations and regional earthquakes. We combined one decade of data collected from 852 permanent and temporary broad-band stations in the region to calculate group-velocity dispersion curves. A compilation of >54 000 ray paths provides reliable group-velocity measurements for periods between 2 and 150 s. Path-averaged group velocities calculated at different periods were inverted for 2-D group-velocity maps. To overcome the problem of heterogeneous ray coverage, we used an adaptive grid parametrization for the group-velocity tomographic inversion. We then sample the period-dependent group-velocity field at each cell of a predefined grid to generate 1-D group-velocity dispersion curves, which are subsequently inverted for 1-D Vs models beneath each cell and combined to approximate the 3-D Vs structure of the area. The Vs model shows low velocities at shallow depths (5–10 km) beneath the Mesopotamian foredeep, South Caspian Basin, eastern Mediterranean and the Black Sea, in coincidence with deep sedimentary basins. Shallow high-velocity anomalies are observed in regions such as the Arabian Shield, Anatolian Plateau and Central Iran, which are dominated by widespread magmatic exposures. In the 10–20 km depth range, we find evidence for a band of high velocities (>4.0 km s–1) along the southern Red Sea and Arabian Shield, indicating the presence of upper mantle rocks. Our 3-D velocity model exhibits high velocities in the depth range of 30–50 km beneath western Arabia, eastern Mediterranean, Central Iranian Block, South Caspian Basin and the Black Sea, possibly indicating a relatively thin crust. In contrast, the Zagros mountain range, the Sanandaj-Sirjan metamorphic zone in western central Iran, the easternmost Anatolian plateau and Lesser Caucasus are characterized by low velocities at these depths. Some of these anomalies may be related to thick crustal roots that support the high topography of these regions. In the upper mantle depth range, high-velocity anomalies are obtained beneath the Arabian Platform, southern Zagros, Persian Gulf and the eastern Mediterranean, in contrast to low velocities beneath the Red Sea, Arabian Shield, Afar depression, eastern Turkey and Lut Block in eastern Iran. Our Vs model may be used as a new reference crustal model for the Middle East in a broad range of future studies.

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The European Alps are the site where classic geologic concepts such as nappe theory, continental subduction, and slab breakoff have been first proposed. However, the deep tectonic structure of the Alps has long been poorly constrained by independent geophysical evidence. This review paper summarizes the main results of the CIFALPS passive seismic experiment, which allows us to propose an updated image of the deep structure of the Alps at the scale of the lithosphere and the upper mantle. The concepts and ideas summarized in this article provide a baseline for further advances in the fields of Alpine tectonics and in the analysis of active continental margins more generally. MALUSÀ ET AL.

SUMMARY We present an improved crustal Vs model and Moho depth map using ambient noise wave-equation tomography. The so-called ‘ambient noise wave-equation tomography’ is a method to invert seismic ambient noise phase dispersion data based on elastic waveform simulation, which accounts for 3-D and finite-frequency effects. We use cross-correlations of up to 4 yr of continuous vertical-component ambient seismic noise recordings from 304 high-quality broad-band stations in the Alpine region. We use model LSP_Eucrust1.0 obtained from traditional ambient noise tomography as initial model, and we iteratively improve the initial model by minimizing frequency-dependent phase traveltime differences between the observed and synthetic waveforms of Rayleigh waves in the period range 10–50 s. We obtain the final model after 15 iterations with ∼65 per cent total misfit reduction compared to the initial model. At crustal depth, the final model significantly enhances the amplitudes and adjusts the shapes of velocity anomalies. At Moho and upper-mantle depth, the final model corrects an obvious systematic velocity shift of the initial model. The resulting isovelocity Moho map confirms a Moho step along the external side of the external crystalline massifs of the northwestern Alps and reveals underplated gabbroic plutons in the lower most crust of the central and eastern Alps. Ambient noise wave-equation tomography turns out to be a useful tool to refine shear wave velocity models obtained by traditional ambient noise tomography based on ray theory.

Purpose: The aim of this study was to compare the ocular microbial communities in humans with and without demodex blepharitis in order to elucidate the relationship between ocular microorganisms and demodex infestation. Methods: Bacterial 16S rRNA genes of conjunctival sac samples from 30 demodex blepharitis patients and 14 healthy controls were sequenced using a pyrosequencing method, and their bacterial community structures were compared by bioinformatics. Results: Bacterial community clustering of conjunctival sac in the demodex blepharitis group were significantly distinct from the healthy control group, with significantly higher relative abundances of Firmicutes and Corynebacterium at the phyla level, as well as higher abundances of Lactobacillus and Bifidobacterium at the genus level. The relative abundance of Staphylococcus epidermidis (0.07–2.27%) was positively correlated with the demodex amount and modified OSDI. The major potential factors contribute to demodex blepharitis were Bacilli, Firmicutes, Cyanobacteria, Lactobacillus and Streptophyta. Conclusions: Patients with demodex blepharitis have varying degrees of bacterial microbiota imbalance in the conjunctival sac. Demodex serving as vectors to transfer both skin and environmental flora might be the potential mechanism. In addition, the number and type of demodex affect the specific ocular surface bacteria, presenting as ocular discomfort and obvious signs of blepharitis.

Summary We examine regional transient changes of seismic velocities generated by the Mw 7.1 2019 Ridgecrest earthquake in California, using autocorrelations of moving time windows in continuous waveforms recorded at regional stations. We focus on travel time differences in a prominent phase generated by an interface around 2 km depth, associated with transmitted Pp waves and converted Ps waves from the ongoing microseismicity. Synthetic tests demonstrate the feasibility of the method for monitoring seismic velocity changes. Taking advantage of the numerous aftershocks in the early period following the mainshock, we obtain a temporal resolution of velocity changes up to 20 min in the early post-mainshock period. The results reveal regional coseismic velocity drops in the top 1–3 km with an average value of ∼2 per cent over distances up to 100 km from the Ridgecrest event. These average velocity drops are likely dominated by larger changes in the shallow materials, and are followed by rapid recoveries on timescales of days. Around the north end of the Ridgecrest rupture and the nearby Coso geothermal region, the observed coseismic velocity drops are up to ∼8 per cent. The method allows monitoring temporal changes of seismic velocities with high temporal resolution, fast computation, and precise spatial mapping of changes. The results suggest that significant temporal changes of seismic velocities of shallow materials are commonly generated on a regional scale by large events.