Hypotension and pruritus induced by neuraxial anaesthesia in a cat

Bauquier, Sébastien H

doi:10.1111/j.1751-0813.2012.00975.x

Cited by 19 publications

(18 citation statements)

References 18 publications

(40 reference statements)

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“…RM-ANOVA revealed a significant effect of propofol and group × time interaction (F[ (2,15] = 46.87, P < 0.001; F [22, 165] = 2.37, P = 0.001); compared with intralipid and normal saline groups, the scratching behavior was significantly attenuated in the propofol group (P < 0.001, Dunnett test) (Fig. 2).…”

Section: Resultsmentioning

confidence: 99%

The Effect of Propofol on Intrathecal Morphine-Induced Pruritus and Its Mechanism

Liu

Zhang

Zhao

et al. 2014

Anesthesia &Amp; Analgesia

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Section: Resultsmentioning

confidence: 99%

The Effect of Propofol on Intrathecal Morphine-Induced Pruritus and Its Mechanism

Liu

Zhang

Zhao

et al. 2014

Anesthesia &Amp; Analgesia

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“…Mild respiratory depression has been reported after epidural administration of 0.1 mg kg −1 of morphine in dogs (6) but this is not clinically relevant (38) if assisted or mechanical ventilation is promptly instituted. Pruritus has also been reported following epidural and intrathecal morphine administration (99–101). The use of a 5-hydroxytryptamine antagonists (e.g., ondansetron) has been described as treatment for neuraxial opioid-induced pruritus (102).…”

Section: Opioidsmentioning

confidence: 99%

An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

Steagall

2017

Front. Vet. Sci.

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This review aims to report an update on drugs administered into the epidural space for anesthesia and analgesia in dogs, describing their potential advantages and disadvantages in the clinical setting. Databases searched include Pubmed, Google scholar, and CAB abstracts. Benefits of administering local anesthetics, opioids, and alpha2 agonists into the epidural space include the use of lower doses of general anesthetics (anesthetic “sparing” effect), perioperative analgesia, and reduced side effects associated with systemic administration of drugs. However, the potential for cardiorespiratory compromise, neurotoxicity, and other adverse effects should be considered when using the epidural route of administration. When these variables are considered, the epidural technique is useful as a complementary method of anesthesia for preventive and postoperative analgesia and/or as part of a balanced anesthesia technique.

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“…To the authors’ knowledge, this is the largest study to date investigating safety and complications in cats receiving epidurals. Case reports exist in the veterinary literature of complications related to lumbosacral epidurals including hypotension, pruritis, chronic urinary and bowel dysfunction, and urinary retention 42‐46 . Because of concerns that urinary retention can occur, cats in this study were required to be hospitalized with an indwelling urinary catheter.…”

Section: Discussionmentioning

confidence: 99%

A prospective randomized, double‐blinded clinical study evaluating the efficacy and safety of bupivacaine versus morphine‐bupivacaine in caudal epidurals in cats with urethral obstruction

Pratt

Balakrishnan

McGowan

et al. 2020

J Vet Emergen Crit Care

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Objective To investigate the efficacy and safety of the caudal epidural technique in cats with urethral obstruction (UO). Design Prospective, double‐blinded, randomized, sham‐controlled study. Animals Eighty‐eight male cats with UO. Interventions Thirty cats randomized to bupivacaine epidural (BUP), 28 cats to bupivacaine‐morphine epidural (BUP/MOR), and 30 cats to sham epidural (SHAM). Measurements and Main Results Time to perform the epidural and efficacy of the epidural was assessed by evaluation of tail and perineal responses. The amount of propofol for urinary catheterization and time to administration of rescue analgesia (buprenorphine) was recorded. Cats were monitored for epidural complications. The median time to perform the epidural was 2 min (range, 0.2‐13 min and range, 0.5‐13 min), with an epidural success rate of 70%. The median amount of propofol administered for urinary catheterization was significantly less in the BUP (2.1 mg/kg; range, 0‐7.5 mg/kg) and MOR/BUP cats (1.85 mg/kg; range, 0‐8.6 mg/kg) as compared to SHAM cats (4 mg/kg; range, 0‐12.7 mg/kg) (P = 0.006, P = 0.0008, respectively). The median time to administration of rescue analgesia was also significantly longer in the BUP (10 h; range, 2‐32 h) and MOR/BUP cats (10 h; range, 4‐45 h) as compared to SHAM cats (4 h; range, 2‐36 h) (P = 0.0026, P = 0.0004, respectively). There were no recognized complications related to the epidural. Conclusion Caudal epidural appears to be safe, may reduce the amount of IV anesthesia needed to facilitate urinary catheterization, and can be used to provide long‐term analgesia in the hospital.

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Hypotension and pruritus induced by neuraxial anaesthesia in a cat

Cited by 19 publications

References 18 publications

The Effect of Propofol on Intrathecal Morphine-Induced Pruritus and Its Mechanism

The Effect of Propofol on Intrathecal Morphine-Induced Pruritus and Its Mechanism

An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

A prospective randomized, double‐blinded clinical study evaluating the efficacy and safety of bupivacaine versus morphine‐bupivacaine in caudal epidurals in cats with urethral obstruction

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