Hypertension and diabetes mellitus as a predictive risk factors for stroke

Alloubani, Aladeen; Saleh, Abdulmoneam; Abdelhafiz, Ibrahim

doi:10.1016/j.dsx.2018.03.009

Cited by 154 publications

(116 citation statements)

References 32 publications

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“…Hypertension is an established risk factor for CeVD and CaVD and therefore known to contribute to the development of dementia and mostly to VaD [8,12,14]. However, studies are not in agreement when it comes to the connection and contribution of HT as a risk factor for AD and LBD [16,18,47,48].…”

Section: Hypertensionmentioning

confidence: 99%

“…It is known that cerebrovascular disease (CeVD) and cardiovascular disease (CaVD) contribute to cognitive impairment and dementia in general [8,10,11]. Hypertension (HT) and diabetes mellitus (DM), both considered risk factors for CeVD and CaVD [8,[12][13][14], are known risk factors for VaD [8] and they have been suggested as risk factors for AD [15][16][17]. However, research on these factors is limited when it comes to LBD.…”

Section: Introductionmentioning

confidence: 99%

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Cardiovascular Disease, Diabetes Mellitus, and Hypertension in Lewy Body Disease: A Comparison with Other Dementia Disorders

Javanshiri

Haglund

Englund

2019

JAD

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Background: Research concerning the potential roles of cardiovascular disease (CaVD) and diabetes mellitus (DM) as risk factors for Lewy body disease (LBD) is limited. These disorders are, however, established risk factors for vascular dementia (VaD) and have been proposed as risk factors for Alzheimer's disease (AD). Objective: The aim of this study was to investigate the prevalence of CaVD and DM in LBD and compare the results with previous findings in cases with AD, VaD, and mixed AD-VaD (MD). Methods: Autopsy reports at the Clinical Department of Pathology in Lund from 2001-2018 were analyzed. All cases with a complete neuropathological diagnosis of LBD were selected, not distinguishing between subjects with clinical Parkinson disease dementia and dementia with Lewy bodies, on the condition of a clinical diagnosis of dementia. Clinical data were retrieved through the patients' medical records and the Swedish National Diabetes Register (NDR) and compared with those of the AD, VaD, and MD cases. Results: In LBD, there was less CaVD, significantly less DM (p = 0.002) and likewise significantly less hypertension (p < 0.001) than in VaD. The results of the LBD group were consistent with the results of the AD group. Conclusion: Our findings of a low prevalence of CaVD and CaVD risk factors in LBD and in AD argue against the association between these risk factors and their contribution to the development of neurodegenerative diseases.

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Section: Hypertensionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cardiovascular Disease, Diabetes Mellitus, and Hypertension in Lewy Body Disease: A Comparison with Other Dementia Disorders

Javanshiri

Haglund

Englund

2019

JAD

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“…A theory of pathophysiology of diabetes with comorbid hypertension that caused the stroke explains atherosclerotic changes in extracranial and intracranial vessels are caused due to insulin resistance by the cells and hyperinsulinemia which cause diabetes and not due to high glucose levels or other risk factors. 21 Regular insulin was used in blood glucose control during the acute phase of stroke given subcutaneously every 6 hours by means of a sliding scale or continuous intravenous infusion. Management of hyperglycemia in the acute phase of stroke, according to The European Stroke Organization guideline, is when the blood glucose levels ≤ 180 mg / dL insulin were not given, insulin delivery started to be given at blood glucose levels > 180 mg/dL.…”

Section: Discussionmentioning

confidence: 99%

Profile of Type 2 Diabetes Mellitus in Acute Thrombotic Stroke

Jordan

Islamiyah

Prayitno

2019

MNJ

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Background: Stroke is a brain disorder in blood circulation that occur suddenly and last more than 24 hours, which is one leading cause of death in the world. One of the main risk factors of stroke is diabetes mellitus type 2. One complication is that when thrombosis occurs in the brain causing a stroke. Objective: This study aimed to determine the profile of type 2 diabetes mellitus in patients with acute thrombotic stroke who were treated in the Neurology Department at the Hospital Dr. Soetomo. Methods: Sampling was done with purposive sampling by observing the medical records of patients in the period of January 2014 to December 2015 based on inclusion and exclusion criterias that have been set. Results: Women with a history of type 2 diabetes are more exposed to acute thrombotic stroke; the age group which is most at risk for stroke is between age of 56-60 years; the average duration of DM until the occurence of stroke is 6,54 ± 4,85 years; more than two-thirds of patients come to the hospital when the acute thrombotic stroke occurs with a condition of hyperglycemia; the most common comorbid disease is hypertension; and insulin therapy is the most widely used therapy in acute thrombotic stroke patients with type 2 diabetes. Conclusion: Managing the risk factors of stroke should prolong or prevent the incident of acute thrombotic stroke since most of the patients with type 2 diabetes mellitus came to the hospital with a condition of hyperglycemia and hypertension.

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“…Ada faktor risiko stroke iskemik yang dapat dimodifikasi dan tidak dapat dimodifikasi. Usia, riwayat keluarga stroke, dan jenis kelamin adalah risiko yang tidak dapat dimodifikasi sedangkan factor risiko yang dapat dimodifikasi yaitu diabetes, hipertensi, kolesterol tinggi, penyakit jantung dan merokok (Alloubani, Saleh and Abdelhafiz, 2012;Rammal and Almekhlafi, 2016).…”

Section: Hasil Dan Pembahasanunclassified

Perbedaan Length of Stay (LOS) Pasien Diabetes Mellitus Berdasarkan Komplikasi Di RSUP Dr. Sardjito Yogyakarta

Salim¹,

Lubis²,

Sugeng

2019

JurnalMIKI

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Complications are the factors that determine the length of the day of treatment of diabetes mellitus patients in the hospital such as hypertension, stroke, coronary heart disease, cholesterol, obesity and others. This study aims to analyze differences in Length of Stay (LOS) of patients with diabetes mellitus based on complications in RSUP Dr. Sardjito Yogyakarta.This research is an analytic observational quantitative research with cross sectional design. The population is all people with diabetes mellitus from year 2011-2016 recorded in electronic medical record. All the population used as research sample that is as many as 1,554 people. Independent variables in this study were hypertension, nephropathy, neuropathy, obesity, CHD, stroke, and pulmonary TB. Dependent variable is Length of Stay or long treatment of diabetes mellitus patient. Data analysis was performed using Independent T test. Diabetes mellitus patients at RSUP Dr. Sardjito year 2011-2016 amounted to 1,554 people with a trend that tends to decline. Most patients were aged 56-63 years (27.86%). The incidence of diabetes mellitus is dominated by type 2 with the highest complications being hypertension, nephropathy, and neuropathy. Based on the result of statistical test, there is a significant difference between the average LOS between patients with diabetes mellitus who have hypertension complications with non-hypertensive (p-value = 0.00), neuropathy with non-neuropathy (p-value = 0.00), coronary heart disease with which is not coronary heart disease (p-value = 0.035), and stroke with non-stroke (p-value = 0.032). Conclusions: There is significant difference in mean LOS among patients with diabetes mellitus who have complications of hypertension, neuropathy, coronary heart disease, and stroke with no complications of the disease.

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Hypertension and diabetes mellitus as a predictive risk factors for stroke

Cited by 154 publications

References 32 publications

Cardiovascular Disease, Diabetes Mellitus, and Hypertension in Lewy Body Disease: A Comparison with Other Dementia Disorders

Cardiovascular Disease, Diabetes Mellitus, and Hypertension in Lewy Body Disease: A Comparison with Other Dementia Disorders

Profile of Type 2 Diabetes Mellitus in Acute Thrombotic Stroke

Perbedaan Length of Stay (LOS) Pasien Diabetes Mellitus Berdasarkan Komplikasi Di RSUP Dr. Sardjito Yogyakarta

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