Hydroxyapatite ceramics with selected sintering additives

Suchanek, Wojciech L.; Yashima, Masatomo; Kakihana, Masato; Yoshimura, Masahiro

doi:10.1016/s0142-9612(97)00019-7

Cited by 196 publications

(129 citation statements)

References 31 publications

Supporting

Mentioning

120

Contrasting

Order By: Relevance

“…Within bone matrix, calcium is important at the whole tissue level, both as a structural component of the mineralized matrix and as a signal transduction molecule for eliciting cellular responses. Owing to its closed structural resemblance to bones and teeth, HAP has attracted much attention as a substitute material for damaged teeth or bones over the last years (Suchanek and Yoshimura 1997;Hench 1991;Ohura et al 1996).…”

Section: Introductionmentioning

confidence: 99%

Effect of preparation conditions on the nanostructure of hydroxyapatite and brushite phases

et al. 2015

View full text Add to dashboard Cite

Hydroxyapatite (HAP) and dicalcium phosphate dihydrate (brushite) nanoparticles were prepared by co-precipitation method. The obtained products were characterized by X-ray powder diffraction (XRD), Fourier transformation infra-red spectroscopy (FTIR) and thermogravimetric analysis (TGA). Scanning electron microscopy (SEM) and transmission electron microscope (TEM) were used to investigate the morphology of the powdered samples as well as their microstructure, respectively. Brushite samples were obtained in a spherical shape, while hydroxyapatite was formed in a needle and rice shape depending on the pH value.

show abstract

Section: Introductionmentioning

confidence: 99%

Effect of preparation conditions on the nanostructure of hydroxyapatite and brushite phases

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Additionally, the stable temperature of α-TCP (1125-1430 °C) differs from that of β-TCP (< 1250 °C), and HAp is stable in a wide range of temperature between 800 °C and 1400°C [20] according to various published literature data. Hence, it can be assumed that after sintered into dense forms, the properties of these three materials would also differ with each other.…”

Section: Research Articlementioning

confidence: 96%

Optimization of Sintering Conditions for Improvement of Mechanical Property of a-Tricalcium Phosphate Blocks

Iy¹

2016

Glob J Biotechnol Biomater Sci

View full text Add to dashboard Cite

Bioactive ceramic materials have been under research as bone substitute for several decades. To repair the high-load bearing bones, mainly cortical bones, there is a need for the substitute to possess comparable mechanical strength to cortical bone, of which the compressive strength ranges between 100 and 230 MPa. Two prevailing bone repairing material, β-tricalcium phosphate (β-TCP, β-Ca 3 (PO 4 ) 2 ) and hydroxyapatite (HAp: Ca 10 (PO 4 ) 6 (OH) 2 ) have been widely researched and sintered into dense blocks to meet the mechanical requirements. α-tricalcium phosphate (α-TCP, α-Ca 3 (PO 4 ) 2 ), a high temperature polymorph of β-TCP, received relatively less attention and α-TCP dense sintered blocks have not been reported yet. In this research, we fabricated α-TCP dense blocks by sintering under various temperatures (1150-1400 °C) and the highest compressive strength was around 230 MPa. Intermediate porous blocks (porosity: 33%) were also fabricated from mixed powder of α-TCP and starch. In vitro properties variation of the intermediate porous blocks were investigated by soaking samples in simulated body fluid (SBF) and the compressive strength was maintained above 100 MPa after soaking for 14 d.

show abstract

“…3) Boron nitride (BN), which is usually used as the dental cement and cosmetics for its unique characteristics profile, has also been used as an additive. Research and development in BN-containing products are brought together for improvement that is enabled by the material in existing processes and in the materials itself.…”

Section: )5)mentioning

confidence: 99%

Characterization of boron nitride-reinforced hydroxyapatite composites prepared by spark plasma sintering and hot press

Prajatelistia

Han

Kim

et al. 2013

J. Ceram. Soc. Japan

View full text Add to dashboard Cite

Hydroxyapatite (HA) has been introduced as a bone grafting material due to its similar composition to that of natural bone, along with its lack of toxicity and high chemical stability, which prevent inflammatory or antigenic reactions. However, the high porosity of HA leads to increased osteoconductive capacity to the implant, while reducing its mechanical resistance and hence limiting its clinical use. Research on the mechanical properties of HA such as superplasticity has been necessary to solve these disadvantages. In this study, boron nitride (BN; 0, 2, 4 wt %) was added as the second phase reinforcement to increase the bone strength and improve the mechanical combination. The BN was added using the appropriate sintering method in order to control the grain size and reduce the chances of HA being dissociated into tricalcium phosphate (TCP) due to the shorter exposure at high temperature. The microstructures of the samples with various percentages of BN-reinforced HA demonstrated some variation. Xray diffraction (XRD) and scanning electron microscopy (SEM) analyses were conducted to determine the elemental composition of the materials and observe the microstructural transformation. As a result, the various percentages of BN-reinforced HA combined with hot press (HP) and spark plasma sintering (SPS) methods demonstrated the improved consolidation of the HA composites with BN, which is a promising result for the development of bioactive load bearing ceramic bone substitution with improved mechanical properties.

show abstract

Hydroxyapatite ceramics with selected sintering additives

Cited by 196 publications

References 31 publications

Effect of preparation conditions on the nanostructure of hydroxyapatite and brushite phases

Effect of preparation conditions on the nanostructure of hydroxyapatite and brushite phases

Optimization of Sintering Conditions for Improvement of Mechanical Property of a-Tricalcium Phosphate Blocks

Characterization of boron nitride-reinforced hydroxyapatite composites prepared by spark plasma sintering and hot press

Contact Info

Product

Resources

About