Hydrophilic surface modification of poly(methyl methacrylate)-based ocular prostheses using poly(ethylene glycol) grafting

Ko, Jeong Hoon; Cho, Kanghee; Han, Sang Won; Sung, Hyung Kyung; Baek, Seung Wook; Koh, Won Gun; Yoon, Jin Sook

doi:10.1016/j.colsurfb.2017.07.017

Cited by 42 publications

(15 citation statements)

References 32 publications

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“…This is confirmed by the present observation. As PMMA is highly hydrophobic [65], the proteins tend to be adsorbed as can be clearly seen in contact images in Fig. 7C and 7D.…”

Section: Discussionmentioning

confidence: 83%

Towards the understanding of lubrication mechanisms in total knee replacements – Part I: Experimental investigations

Nečas

Vrbka

Marian

et al. 2021

Tribology International

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“…This is confirmed by the present observation. As PMMA is highly hydrophobic [65], the proteins tend to be adsorbed as can be clearly seen in contact images in Fig. 7C and 7D.…”

Section: Discussionmentioning

confidence: 83%

Towards the understanding of lubrication mechanisms in total knee replacements – Part I: Experimental investigations

Nečas

Vrbka

Marian

et al. 2021

Tribology International

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“…The cytotoxicity of the materials used for 3D printing was evaluated using the method described in our previous study 16 . Specifically, samples of 3D-printed polymer resin were prepared in the form of 1 × 1 × 1 cm blocks, and samples of poly(methyl methacrylate) (PMMA)—the material used to fabricate most modern ocular prostheses—were prepared in the same shape and size.…”

Section: Methodsmentioning

confidence: 99%

Semi-automated fabrication of customized ocular prosthesis with three–dimensional printing and sublimation transfer printing technology

Kim

Baek

et al. 2019

Sci Rep

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An ocular prosthesis is a custom-made polymeric insert that can be placed in an anophthalmic socket for cosmetic rehabilitation of patients who have lost their eyes. The process of creating such a custom-made ocular prosthesis is time-consuming and labor-intensive because it involves artistic work that is carried out manually. This paper proposes a novel semi-automated method for fabricating customized ocular prostheses using three-dimensional (3D) printing and sublimation transfer printing. In the proposed method, an impression mold of the patient’s anophthalmic socket is first optically scanned using a 3D scanner to produce a 3D model. The ocular prosthesis is then produced via a digital light processing 3D printer using biocompatible photopolymer resin. Subsequently, an image of the iris and blood vessels of the eye is prepared by modifying a photographed image of the contralateral normal eye, and printed onto the 3D-printed ocular prosthesis using a dye sublimation transfer technique. Cytotoxicity assessments of the base material and fabricated ocular prosthesis indicate that there is no adverse effect on cellular viability and proliferation. The proposed method reduces the time and skill required to fabricate a customized ocular prosthesis, and is expected to provide patients with easier access to quality custom-made ocular prostheses.

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“…However, all may not be bad for PMMA, as van der Worp discussed the relevance of PMMA as scleral lenses [73]. In addition, PEG grafted onto PMMA is seen as a prosthetic eye replacement [74]. Overall, these are only a few works amongst an enormous amount of literature on contact lenses.…”

Section: Contact Lens Materialsmentioning

confidence: 99%

Contact Lens Materials: A Materials Science Perspective

2019

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More is demanded from ophthalmic treatments using contact lenses, which are currently used by over 125 million people around the world. Improving the material of contact lenses (CLs) is a now rapidly evolving discipline. These materials are developing alongside the advances made in related biomaterials for applications such as drug delivery. Contact lens materials are typically based on polymer- or silicone-hydrogel, with additional manufacturing technologies employed to produce the final lens. These processes are simply not enough to meet the increasing demands from CLs and the ever-increasing number of contact lens (CL) users. This review provides an advanced perspective on contact lens materials, with an emphasis on materials science employed in developing new CLs. The future trends for CL materials are to graft, incapsulate, or modify the classic CL material structure to provide new or improved functionality. In this paper, we discuss some of the fundamental material properties, present an outlook from related emerging biomaterials, and provide viewpoints of precision manufacturing in CL development.

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Hydrophilic surface modification of poly(methyl methacrylate)-based ocular prostheses using poly(ethylene glycol) grafting

Cited by 42 publications

References 32 publications

Towards the understanding of lubrication mechanisms in total knee replacements – Part I: Experimental investigations

Towards the understanding of lubrication mechanisms in total knee replacements – Part I: Experimental investigations

Semi-automated fabrication of customized ocular prosthesis with three–dimensional printing and sublimation transfer printing technology

Contact Lens Materials: A Materials Science Perspective

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