Hybrid lesion: central giant cell granuloma and benign fibro-osseous lesion

Crusoé‐Rebello, Iêda; Torres, Marianna Guanaes Gomes; Burgos, Valdelice Oliveira; Oliveira, Catarina Rodrigues Rosa De; Santos, Jean Nunes dos; Azevedo, Roberto Almeida de; Campos, P. S. F.

doi:10.1259/dmfr/44753298

Cited by 19 publications

(23 citation statements)

References 11 publications

(18 reference statements)

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“…The authors described the importance of CT in lesion mapping and treatment planning. In another case report (14), a CGCL was associated with a fibro-osseous lesion and the authors emphasized that the CT images were important to reveal the localization, nature and extent of the lesion.…”

Section: Discussionmentioning

confidence: 99%

Clinical and imagiological findings of central giant cell lesion and cherubism

Pinheiro

Júnior

et al. 2013

Braz. Dent. J.

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Cone beam computed tomography (CBCT) is the best examination for bone lesions of the maxilla, allowing the dentist to evaluate precisely the behavior and components of the lesion and their relationship to the surrounding structures. Central giant cell lesion and cherubism are histologically very similar lesions. Therefore clinical and radiological examinations are fundamentally important for the diagnosis. The aim of this paper is to report two cases diagnosed as central giant cell lesions and cherubism using CBCT. This imaging modality was very important for the diagnosis of the lesions presented in the current study. It also allowed observing precisely the limits of the lesions, the components, the behavior and the exact relationship to adjacent structures.

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Section: Discussionmentioning

confidence: 99%

Clinical and imagiological findings of central giant cell lesion and cherubism

Pinheiro

Júnior

et al. 2013

Braz. Dent. J.

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“…multi nucleated giant cells (MGCs) and spindle shaped stromal cells [2][3][4][5][6][7][8][9]. The latter are thought to be proliferating tumour cells and they form the active cycling compartment.…”

Section: Discussionmentioning

confidence: 99%

“…The latter are thought to be proliferating tumour cells and they form the active cycling compartment. Histologically, in a giant cell containing lesion, haemorrhage occurs with intact areas of frank or partially degenerated RBCs and numerous MGCs and spindle cells are also observed in the stroma, along with mononuclear fibrohistiocytic cells [9,10].…”

Section: Discussionmentioning

confidence: 99%

Fibrous Dysplasia and Central Giant Cell Granuloma: A Report of Hybrid Lesion with its Review and Hypotheticated Pathogenesis

Kurra¹

2013

JCDR

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Benign fibro-osseous lesions (BFOLS) of the jaws are a wide array of lesions that actually represent distinct phases of a single benign morphological process. These lesions share certain histopathological features which are in common with giant cell containing lesions, which include central giant cell granulomas (CGCGs). The association of BFOLS and CGCG has to be critically evaluated, pertaining to their clinical, radiologic and histologic features. Many pathologists diagnose these types of lesions, considering only one of the prominent features. Eventually, surgeons end up treating these lesions inadequately. This ambiguity may be because of very small number of cases have been reported in the literature, with uncertain clinical, radiologic and histologic features. We are reporting a case of fibrous dysplasia (FD) which was associated with a central giant cell granuloma (CGCG) and discussing the hypothetical pathogenesis of giant cells.

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“…2 It is most prevalent in patients younger than 40 years and is more common in the anterior area of the jaw.…”

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confidence: 99%

“…An acquired defect of the nasal septum may be due to causes such as trauma, 1 infection, and resection of tumor. 2 However, a congenital nasal septal defect of vomeral bone is a very rare nasal anomaly, 3Y5 and few reconstructed cases have been reported. There has been a report of a congenital nasal septal defect in a patient with thalassemia.…”

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confidence: 99%