Hyaluronic acid containing hydrogels for the reduction of protein adsorption

Beek, Mark van; Jones, Lyndon; Sheardown, Heather

doi:10.1016/j.biomaterials.2007.10.039

Cited by 118 publications

(104 citation statements)

References 29 publications

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“…68 this situation, the composition of the products suggested here and the delivery methods in liquid suspensions will generate very little, if at all, debris from the surface of the implants, but this is also an issue that must be analyzed in vivo. In fact, for hyaluronic acid, current research 124,144 suggests its viscoelastic and wetting properties may actually be an advantage when delivered in solution, acting to protect the implant surface from released debris and particulates.…”

Section: Selection Criteria For a (Bio)materials To Function As Regenementioning

confidence: 97%

Bioengineering the Skin–Implant Interface: The Use of Regenerative Therapies in Implanted Devices

Peramo

Marcelo

2010

Ann Biomed Eng

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This discussion and review article focuses on the possible use of regenerative techniques applied to the interfaces between skin and medical implants. As is widely known, the area of contact between an implant and the skin--the skin-implant interface--is prone to recurrent and persistent problems originated from the lack of integration between the material of the implant and the skin. Producing a long-term successful biointerface between skin and the implanted device is still an unsolved problem. These complications have prevented the development of advanced prosthetics and the evolution of biointegrated devices with new technologies. While previous techniques addressing these issues have relied mostly on the coating of the implants or the modification of the topology of the devices, recent in vitro developed techniques have shown that is possible to introduce biocompatible and possibly regenerative materials at the skin-device interface. These techniques have also shown that the process of delivering the materials has biological effects on the skin surrounding the implant, thus converting bioinert into bioactive, dynamic interfaces. Given that the best clinical outcome is the long-term stabilization and integration of the soft tissue around the implant, this article presents the basis for the selection of regenerative materials and therapies for long-term use at the skin-device interface, with focus on the use of natural biopolymers and skin cell transplantation.

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Section: Selection Criteria For a (Bio)materials To Function As Regenementioning

confidence: 97%

Bioengineering the Skin–Implant Interface: The Use of Regenerative Therapies in Implanted Devices

Peramo

Marcelo

2010

Ann Biomed Eng

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“…O AH é usado no tratamento de doenças degenerativas e inflamatórias das articulações dos ossos, na reposição do fluído sinovial e na liberação de agentes quimioterápicos em implantes cirúrgicos, como meio hidratante e como sistema para encapsulação e liberação controlada de fármacos e cosméticos (OGRODOWSKI, 2006). Ele também é aplicado em lentes de contato (Beek et al, 2008) e em aplicações vasculares, como um copolímero com propriedades antitrombóticas (XU et al, 2008).…”

Section: Introductionunclassified

Atividade antioxidante do ácido hialurônico extraído da crista de frango

Rosa¹,

Hoelzel²,

Viera³

et al. 2008

Cienc. Rural

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“…Studies have shown that the hyaluronic acid is not only a lubricant with dermatologic and ophthalmologic applications but also can be used in a control system for drug release, as in anesthesia prolongation in bones and joints (GOLDENHEIN et al, 2001), arthropathy treatment (SUZUKI et al, 2001), chemotherapeutic agents in surgical implants (AEBISCHER et al, 2001), drug release in dental caries (SUHONEN & SCHUG, 2000), controlled antigen release for immunotherapy (PARDOLL et al, 2001), and contact lenses (BEEK et al, 2008), and as a copolymer with anti-thrombotic properties in vascular applications (XU et al, 2008).…”

Section: Introductionmentioning

confidence: 99%