Human Seminal Biochemistry: Fructose, Ascorbic Acid, Citric Acid, Acid Phosphatase and their Relationship with Sperm Count

Abstract

The sperm count has been correlated with the concentration of different substances secreted by the adnexal glands with conflicting results.In order to assess their diagnostic significance in male infertility the following substances were measured in seminal plasma: fructose and ascorbic acid produced by seminal vesicles and acid phosphatase and citric acid by the prostate gland. A statistical evaluation was made with the data obtained from azoospermic, oligozoospermic and control subjects.

Aminopeptidase in Human Seminal Plasma

“…Previously, Ishibe et al (1971) and reported that the leucine aminopeptidase activity decreases as sperm count declines. Similar correlation was observed by Jathar and Rashmi (1977) and Videla et al (1981) between sperm count and seminal plasma acid phosphatase activity which is known to be directly androgen dependent (Engberg et al -1974;Ostrowski -1980). Similar correlation was observed by Jathar and Rashmi (1977) and Videla et al (1981) between sperm count and seminal plasma acid phosphatase activity which is known to be directly androgen dependent (Engberg et al -1974;Ostrowski -1980).…”

“…Present investigation however shows a significantly higher aminopeptidase activity in seminal fluid of non-obstructive azoospermic patients than that of other groups ( Table 2), suggesting an inverse relationship between aminopeptidase activity and sperm concentration. Similar correlation was observed by Jathar and Rashmi (1977) and Videla et al (1981) between sperm count and seminal plasma acid phosphatase activity which is known to be directly androgen dependent (Engberg et al -1974;Ostrowski -1980). The higher activity of acid phosphatase in non-obstructive azoospermic group is probably due to hyperplasia of testicular Leydig cell and increased androgen secretion (Phadke et al -1973).…”

Seminal Fructose Concentration in Man Infertility and the Fructose Test's Meaning In Diagnosis Reason of Azoospermia Man

“…The purpose of the studies is using seminal fructose test to replace percutaneous epididymis sperm aspiration (PESA) to diagnosis CBAVD. Fructose is essential for spermatozoa metabolism and spermatozoa motility [5]. Fructose is an energy source for spermatozoa.…”

Assessment of the level of seminal zinc and fructose concentration in seminal plasma of Vietnamese infertile men

“…5,6 Fructose is essential for spermatozoa metabolism and spermatozoa motility. 7 Fructose is an energy source for spermatozoa. It is produced by the seminal vesicles with some contribution from the ampulla of the ductus deferens.…”