Hubungan Staging Kanker Paru dengan Skala Nyeri pada Pasien Kanker Paru yang Dirawat di Bagian Paru RSUP DR M Djamil Padang

Ananda, Rian Rizki; Ermayanti, Sabrina; Abdiana, Abdiana

doi:10.25077/jka.v7.i3.p430-435.2018

Cited by 4 publications

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“…21 Menurut penelitian Ananda RR, et al (2018) dan Anwar A, et al (2014), lebih dari 97% pasien yang menjadi subjek pada penelitian tersebut adalah kanker paru jenis NSCLC. 24,25 Hasil serupa juga didapatkan pada penelitian Aliya NK, et al (2019) dengan lebih dari 92%. 26 Bahkan pada penelitian Dana H Putra, et al (2016), menunjukkan bahwa seluruh pasiennya memiliki jenis kanker paru tersebut.…”

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“…27 Berdasarkan data penelitian tersebut, didapatkan hasil bahwa kanker jenis NSCLC memiliki prevalensi yang jauh lebih besar apabila dibandingkan dengan SCLC. [21][22][23][24][25][26][27][28][29][30] Adenokarsinoma masih menjadi varian NSCLC yang mendominasi gambaran histopatologi kanker paru. Data penelitian yang telah dilakukan menunjukkan bahwa adenokarsinoma masih menjadi jenis kanker paru yang paling sering dijumpai, sesuai dengan prevalensinya yang memang besar.…”

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Literature Review: Pengaruh Rokok terhadap Gambaran Histopatologi Kanker Paru

2022

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Kanker paru menempati urutan nomor dua jenis kanker yang paling sering terdiagnosis serta penyebab kematian nomor satu akibat kanker di dunia. Faktor risiko utama kanker paru adalah terdapatnya riwayat merokok pada pasien. Riyawat merokok memiliki pengaruh terhadap gambaran histopatologi pasien kanker paru. World Health Organization (WHO) 2015 menjelaskan terdapat lima klasifikasi dari tumor paru yaitu tumor epithelial, mesenkimal, limfohistiositik, tumours of ectopic origin dan tumor metastatik. Tumor epithelial merupakan kelompok tumor paru terbanyak. Tujuan dari literature review ini adalah untuk mengetahui apakah gambaran histopatologi pada pasien terdiagnosis kanker paru dapat dipengaruhi oleh riwayat merokok dari pasien tersebut. Metode yang digunakan pada studi ini dengan cara pencarian artikel dalam database jurnal penelitian, pencarian melalui internet, dan tinjauan ulang artikel menggunakan Google scholar dan Pubmed. Berdasarkan hasil penelitian yang didapatkan dalam literature review ini, dapat disimpulkan bahwa Non-Small Cell Lung Cancer (NSCLC) varian karsinoma sel skuamosa dan Small Cell Lung Cancer (SCLC) yang merupakan tumor neuroendokrin adalah jenis kanker paru yang memiliki hubungan paling erat dengan riwayat merokok, namun secara keseluruhan adenokarsinoma masih menjadi jenis kanker paru dengan prevalensi terbesar yang disebabkan oleh beberapa alasan.

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Literature Review: Pengaruh Rokok terhadap Gambaran Histopatologi Kanker Paru

2022

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“…16,18,19 This nicotine content acts as an prooxidant or free radicals that can trigger inflammation to cause cancer. 20 Active free radicals can attack cellular components of the body such as lipid compounds, carbohydrates, and proteins that will cause damage to both cell structure and function. 21 The effect is not only caused by nicotine, other subtances such as propylene glycol are using for the solvent and the flavour also taking part cause the lungs damage.…”

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confidence: 99%

THE EFFECT OF GARLIC (Allium sativum) EXTRACT ON THE HISTOPATOLOGICAL LUNG OF BALB/C MICE WITH NICOTINE EXPOSURE

Mahardika

Armalina

Purnawati

et al. 2022

DMJ

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Background: Nicotine is a major aspect of smoking. Nicotine cause damage to the lungs because the oxidative stress caused triggers an inflammatory response and lung damage to the alveoli. Garlic extract as an antioxidant agent so that it can against oxidative stress caused by nicotine exposure.Objective: This study is to proving the effect of multilevel dose of garlic extract on lung histopathology of BALB/c mice exposed to nicotine by inhalationMethods: The study used an experimental post test only control group design which was carried out for 24 days. Mice were given an adaptation period of 7 days followed by a treatment period of 14 days. On the last day, the lungs will be terminated and taken for histopathological tests. Mice were divided into 4 groups, namely a Healthy Control Group that was only given standard feed, a Negative Control Group that was given exposure to nicotine by inhalation at a dose of 10 mg/KgBW, treatment group 1 was given garlic extract 300 mg/KgBW orally and exposed to nicotine inhalation with a dose of 10 mg/KgBW, and treatment group 2 who were given garlic extract 500 mg/KgBW orally and exposed to nicotine by inhalation at a dose of 10 mg/KgBW. Histopathological preparations were made on each sample with Hematoxylin-Eosin paint which was then observed microscopically and assessed for severity of damage using scoring criteria.Results: Based on microscopic observations, the degree of lung damage is grouped into normal, mild, moderate, and severe degrees. The results in each group are in the following groups: Healthy Control Group : 73%,27%,0%,0% ; C(-) :0%,0%,33%,67% ; T1 : 0%,33%,67%,0% ; T2 : 0%,100%,0%,0%. The Kruskal Wallis test was performed to obtain significant differences, followed by the Mann Whitnney test which compared the treatment groups which showed significant results.Conclusion: By Giving garlic extract can reduce the degree of microscopic damage of mice lung due to nicotin inhalation exposure.

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“…Kan ker adalah istilah yang digunakan untuk penyakit dimana sel-sel abnormal membelah tanpa kontrol dan mampu menyerang jaringan sel lain. Sel-sel kanker dapat menyebar ke bagian lain tubuh melalui pembuluh darah dan sistem limfe [2]. Kanker bukan hanya satu penyakit tapi banyak penyakit, ada lebih dari 100 berbagai jenis penyakit kan ker [1].…”

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Komparasi Algoritma Klasifikasi Data Mining untuk Memprediksi Tingkat Kematian Dini Kanker dengan Dataset Early Death Cancer

Rahayuningsih

2019

JOINTECS

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Cancer is something big in the world. Cancer is a malignant disease that is difficult to cure if the spread is too wide. However, detecting cancer cells as early as possible can reduce the risk of death. This study aims to predict the level of early detection of disasters in European countries using 5 classification algorithms, namely: Desecion Tree, Naïve Bayes, k-Nearset Neighbor, Random Forest and Neural Network of which algorithm is the best for this study. Tests carried out with several stages of research include: dataset (data contains), initial data processing, proposed method, credit method using 10 times cross validation, test results and t-test different tests. The alpha value is 0.05. if the probability is> 0.05 then H0 is accepted. If the probability is <0.05 then Ho is rejected. The results of the research that obtained performance with an accuracy value of 98.35% were the Neural Network algorithm. Whereas, the results of the research usi ng the algirtic t-test with the best models are: Random Forest algorithm and Neural Network, the relatively good Naïve Bayes algorithm, the Desecion Tree algorithm is quite good and the poor algorithm is the K- Nearset Neighbor (K-NN) algorithm.

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Hubungan Staging Kanker Paru dengan Skala Nyeri pada Pasien Kanker Paru yang Dirawat di Bagian Paru RSUP DR M Djamil Padang

Cited by 4 publications

References 0 publications

Literature Review: Pengaruh Rokok terhadap Gambaran Histopatologi Kanker Paru

Literature Review: Pengaruh Rokok terhadap Gambaran Histopatologi Kanker Paru

THE EFFECT OF GARLIC (Allium sativum) EXTRACT ON THE HISTOPATOLOGICAL LUNG OF BALB/C MICE WITH NICOTINE EXPOSURE

Komparasi Algoritma Klasifikasi Data Mining untuk Memprediksi Tingkat Kematian Dini Kanker dengan Dataset Early Death Cancer

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