Homolytic Cleavage of the O-glycoside Bond in Carbohydrates: A Steady-state Radiolysis Study

Abstract

The formation of products resulting from the O-glycoside bond cleavage following radiolysis of aqueous solutions of methyl-alpha-D-glucopyranoside (I), 3-O-methyl-alpha-D-glucopyranose (II), maltose, lactose, gentiobiose and cellobiose were studied. Radiation-induced destruction yields were also determined for dextran, laminarin and trimethylcelulose upon irradiation of their aqueous solutions. Oxygen, quinones and compounds capable of forming quinoid structures were found to inhibit radiation-induced homolytic destruction processes taking place in glycosides, di- and polysaccharides. The data obtained in this study enabled the authors to demonstrate an important role played by the fragmentation reaction of C-2 radicals which were generated from the starting substances in the formation of final radiolysis products.

Non-Enzymatic Methylglyoxal Formation From glucose Metabolites and Generation of Superoxide Anion Radical During Methylglyoxal-Dependent Cross-Links Reaction

“…Our previous studies [25][26][27] proved that the fragmentation of hydroxyl-containing organic compounds procceding in parallel with (proceeding vis-à-vis) the formation of carbon-centered radicals is possible under hypoxic conditions ( Figure 3).…”

Microwave initiated synthesis of polyacrylamide grafted Psyllium and its application as a flocculant

“…Consequently, they may damage the structural integrity of the backbone polymer by breaking the essential bonds. There is always a strong probability of radiation damage (radiolysis) to the polysaccharide backbone [14][15][16][17][18][19]. This method is perfectly fit for synthesis in case of fluoro-polymers, which are exceptionally stable [20][21][22].…”

Microwave assisted synthesis of polyacrylamide grafted agar (Ag-g-PAM) and its application as flocculant for wastewater treatment

“…However, the high energy radiations make no distinction between the bonds to be broken and the bonds essential for structural integrity of the preformed/backbone polymer. There is always a strong probability of radiation damage (radiolysis) to the polysaccharide backbone [22][23][24][25][26][27]. The processes of high energy radiation induced graft copolymerization are especially suitable for fluro-polymers, due to their exceptional stability [28][29][30][31][32][33][34][35][36].…”