History of dementia and dementia in history: An overview

Boller, François; Forbes, Margaret

doi:10.1016/s0022-510x(98)00128-2

Cited by 91 publications

(55 citation statements)

References 53 publications

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“…As an example, Alzheimer's disease was considered as a rare disease until the end of the 1970s, but a better understanding of the disease and its delineation from dementia increased the number of diagnoses and deaths classified as Alzheimer's since (Boller and Forbes 1998). Progress in perception and knowledge of this disease is still ongoing.…”

Section: Discussionmentioning

confidence: 99%

Changes in cause-specific mortality among the elderly in Canada, 1979–2011

Bergeron-Boucher

Bourbeau

Légaré

2017

CSP

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The structure of causes of death in Canada has been changing since the onset of the "cardiovascular revolution." While mortality due to cardiovascular diseases has been declining, mortality due to other causes of death, such as cancers and Alzheimer's disease has been increasing. Our research investigates how these changes have re-modeled life expectancy at age 65 and age 85, and what specific causes of death are involved. We distinguish between premature and senescent deaths in Canada, using a cause-specific age structure. Our results suggest that although a decline in premature deaths has contributed to increasing life expectancy in recent years, most of the gains in life expectancy at age 65 and 85 have resulted from a decline in senescent deaths. We also find a decline in mortality due to the main causes of death, leading to a greater diversification of causes.Keywords: Causes of death, life expectancy, age patterns of mortality, Canada, decomposition. RésuméDepuis le début de la révolution cardiovasculaire, le Canada a connu d'importants changements dans la distribution des décès selon la cause. La mortalité par maladies cardiovasculaires a connu une importante diminution alors que les taux de mortalité pour les cancers et pour la maladie d'Alzheimer ont augmenté. Cet article examine comment ces changements ont influencé les tendances de l'espérance de vie à 65 et à 85 ans et quelles causes de décès spécifiques furent impliquées. Une distinction entre les décès prématurés et les décès liés à un processus de sénescence est réalisée, se basant sur deux indicateurs de variations par âge des causes de décès. Nos résultats suggèrent que la majorité des gains en espérance de vie à 65 et 85 ans proviennent d'une plus faible mortalité par cause de décès sénescente. De plus, une diminution des principales causes de décès chez les personnes âgées de 65 ans et plus laisse place à une plus grande diversification de causes aux grands âges.

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Section: Discussionmentioning

confidence: 99%

Changes in cause-specific mortality among the elderly in Canada, 1979–2011

Bergeron-Boucher

Bourbeau

Légaré

2017

CSP

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“…Dementia appeared in medical texts during antiquity to describe clinical syndromes of diminished cognitive function associated with a variety of neurological conditions (Boller and Forbes 1998). Over time dementia evolved from a broad concept that included any type of mental incapacitation, reversible or irreversible, into a modern diagnosis with highly specialized clinical meaning that itself continued to change, including very recently.…”

Section: Dementia Diagnosis Disease Burdenmentioning

confidence: 99%

The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline

et al. 2016

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The World Health Organization reports that 47.5 million people are affected by dementia worldwide. With aging populations and 7.7 million new cases each year, the burden of illness due to dementia approaches crisis proportions. Despite significant advances in our understanding of the biology of Alzheimer’s disease, the leading dementia diagnosis, the actual causes of dementia in affected individuals are unknown except for rare fully penetrant genetic forms. Evidence from epidemiology and pathology studies indicates that damage to the vascular system is associated with an increased risk of many types of dementia. Both Alzheimer’s pathology and cerebrovascular disease increase with age. How Alzheimer’s disease affects small blood vessel function and how vascular dysfunction contributes to the molecular pathology of Alzheimer’s are areas of intense research. The science of vascular contributions to cognitive impairment and dementia (VCID) integrates diverse aspects of biology and incorporates the roles of multiple cell types that support the function of neural tissue. Because of the proven ability to prevent and treat cardiovascular disease and hypertension with population benefits for heart and stroke outcomes, it is proposed that understanding and targeting the biological mechanisms of VCID can have a similarly positive impact on public health.

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“…Recently, the number of people suffering from AD is estimated in 35 million and the number is expected to raise to 110 million by the year 2050. As the number of elderly population affected by AD rises, the need for making available to the community innovative, accurate, inexpensive and noninvasive diagnostic techniques for early screening of population at risk is becoming a relevantly urgent public health concern [15], [16]. Many researches have shown that the EEG of patients suffering from AD start to modify well in advance of the clinical diagnosis.…”

Section: Effects Of Alzheimer's Disease On Eegmentioning

confidence: 99%

Effects of Artifacts Rejection on EEG Complexity in Alzheimer’s Disease

Labate

Foresta

Mammone

et al. 2015

Smart Innovation, Systems and Technologies

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Abstract. EEG complexity analysis has recently been shown to help to diagnose Alzheimer's Disease (AD) in the early stages. The complexity study is based on the processing of continuous artifact-free Electroencephalography (EEG). Therefore, artifact rejection is normally required because artifacts might mimic cognitive or pathologic activity and therefore bias the neurologist visual interpretation of the EEG. Furthermore, the EEG complexity analysis is strongly altered by artifacts. In this paper, we evaluate the effects of artifacts rejection by a promising technique, Automatic Wavelet-Independent Component Analysis (AWICA), on the EEG Complexity in AD patients. We also investigate the EEG complexity before and after artifact rejection through some measures based on Shannon's Entropy, Renyi's Entropy and Tsallis's Entropy.

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History of dementia and dementia in history: An overview

Cited by 91 publications

References 53 publications

Changes in cause-specific mortality among the elderly in Canada, 1979–2011

Changes in cause-specific mortality among the elderly in Canada, 1979–2011

The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline

Effects of Artifacts Rejection on EEG Complexity in Alzheimer’s Disease

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