History of Cyclodextrins

Morin‐Crini, Nadia; Fourmentin, Sophie; Fenyvesi, Éva; Lichtfouse, Éric; Torri, Giangiacomo; Fourmentin, Marc; Crini, Grégorio

doi:10.1007/978-3-030-49308-0_1

Cited by 17 publications

(19 citation statements)

References 398 publications

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“…Pringsheim is recognized as the first researcher to have published prolifically on dextrins. However, the works were repetitive, marred by frequently contradictory results and by even hot debate between the two groups (French 1957a;Szejtli 1998;Crini 2014Crini , 2020aMorin-Crini et al 2015).…”

Section: The Foundation Of the Cyclodextrin Chemistrymentioning

confidence: 99%

“…Four substances, i.e., α-diamylose, α-tetraamylose, α-hexaamylose, and α-octaamylose, were included in the α-series of dextrins, while the β-series only contained two substances, i.e., β-triamylose and β-hexaamylose. Indeed, for Pringsheim, the Schardinger dextrins arose through the bacterial depolymerization of starch to the fundamental units: the amylose fraction being broken down into the α-series of dextrins, i.e., polyamyloses, and the amylopectin fraction being degraded to the β-series (French 1957a;Thoma and Stewart 1965;Caesar 1968;Szejtli 1998;Morin-Crini et al 2015;Crini 2020b). Pringsheim also used the terms of α-amylosan, α-allo-amylosan and α-iso-amylosan, and β-amylosan, β-allo-amylosan and β-isoamylosan for α-dextrin and β-dextrin, respectively (Crini 2014).…”

Section: Nomenclaturementioning

confidence: 99%

“…For Karrer, these two products were identical. In addition, Karrer regarded maltose as the fundamental unit of the whole of the starch molecule while Pringsheim considered the polyamyloses as the basic units of the starch molecule (French 1957a;Thoma and Stewart 1965;Caesar 1968;Szejtli 1998;Morin-Crini et al 2015). Like Pringsheim, Karrer also used the amylosan-based terminology (Crini 2014).…”

Section: Nomenclaturementioning

confidence: 99%

“…Figure 1 shows that cyclodextrins occur in many daily products such as an ibuprofen tablet, a non-steroidal antiinflammatory drug, a whooping cough vaccine, a curative antidote, a hair loss solution, a stop smoking aid, toothpastes, shampoo, colognes, a deodorant toilet, razors, a turmeric-based food supplement, a butter, a mayonnaise, fish sausages, modified steaks, a horseradish powder, mustard sauces, a sweetener, honey, a cinnamon extract, green tea without bitterness, vanilla coffee, clarified fruit juices, chewing gums, chromatographic columns, biopesticides, catalysts, tubular materials, a curtain, cosmetotextiles, an ink, a detergent, a bioflocculant for swimming pool, or a bioadsorbent for water treatment (Morin-Crini et al 2015;Crini et al 2018;Fourmentin et al 2018a, b).…”

Section: Introductionmentioning

confidence: 99%

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130 years of cyclodextrin discovery for health, food, agriculture, and the industry: a review

et al. 2021

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Cyclodextrins are a group of cyclic oligosaccharides obtained by enzymatic degradation of starch. They are remarkable macrocyclic molecules that have led major theoretical and practical advances in chemistry, biology, biochemistry, health science, and agriculture. Their molecular structure is composed of a hydrophobic cavity that can encapsulate other compounds to form inclusion complexes through host-guest interactions. This unique feature is at the origin of many applications. Cyclodextrins and their derivatives have a wide variety of practical applications in almost all sectors of the industry, including pharmacy, medicine, foods, cosmetics, chromatography, catalysis, biotechnology, and the textile industry. Villiers published the first reference to cyclodextrins in 1891, and since then, these molecules have continued to fascinate academia and industry. Currently, more than 2000 publications on cyclodextrins are published each year. On the occasion of the 130th anniversary of their discovery, in this review, we present an historical overview of the development and applications of cyclodextrins. First, we present the discovery and first chemical studies on cyclodextrins. Then, the main results obtained during the 1911-1970 exploration period are discussed. A third part presents the historical landmarks in the development of cyclodextrins from 1970 to the present day.

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Section: The Foundation Of the Cyclodextrin Chemistrymentioning

confidence: 99%

Section: Nomenclaturementioning

confidence: 99%

Section: Nomenclaturementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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130 years of cyclodextrin discovery for health, food, agriculture, and the industry: a review

et al. 2021

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“…Cyclodextrins (CDs) are a family of macromolecules composed of α-1,4-linked D-glucopyranoside subunits obtained by enzymatic degradation of starch [ 1 ]. Their structure resembles a truncated cone, with a somewhat lipophilic central cavity and an external hydrophilic surface.…”

Section: Introductionmentioning

confidence: 99%

Cyclodextrin Multicomponent Complexes: Pharmaceutical Applications

et al. 2021

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Cyclodextrins (CDs) are naturally available water-soluble cyclic oligosaccharides widely used as carriers in the pharmaceutical industry for their ability to modulate several properties of drugs through the formation of drug–CD complexes. The addition of an auxiliary substance when forming multicomponent complexes is an adequate strategy to enhance complexation efficiency and to facilitate the therapeutic applicability of different drugs. This review discusses multicomponent complexation using amino acids; organic acids and bases; and water-soluble polymers as auxiliary excipients. Special attention is given to improved properties by including information on the solubility, dissolution, permeation, stability and bioavailability of several relevant drugs. In addition, the use of multicomponent CD complexes to enhance therapeutic drug effects is summarized.

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Co‐Aggregation Induced by Amphiphilic Membrane Interface for the Capture of Trace Endocrine Disruptors from Water

Ouyang

Gui

Liu

et al. 2022

Adv Materials Inter

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Endocrine disruptors (EDCs) are widely detected in water resources owing to the abuse of plastic products, posing a serious global concern. Unfortunately, the rapid, effective, and economical removal of trace EDCs from water remains a significant challenge. Herein, a novel adsorptive membrane (PVPM) with excellent recyclability and stability is prepared by the UV‐initiated grafting of poly(N‐vinylpyrrolidone) (PNVP) onto the surface of polypropylene fibrous membrane (PPM). The PVPM exhibits high flux, low‐pressure drop, and excellent adsorption performance. It can efficiently capture trace (10 µg L−1) EDCs with a removal efficiency of 99%. Notably, the adsorption performance of the PVPM remains unchanged even in river water. A mechanism for the adsorption is proposed based on adsorption kinetics and thermodynamics. Specifically, dynamic hydrophobic microdomains are generated between amphiphilic PNVP and EDCs and form co‐aggregates on the PPM substrate. This co‐aggregation is responsible for the large adsorption capacity for EDCs. A large decrease in the free energy (−16.65 kJ mol−1) of the adsorption process provides additional evidence for the strong adsorption affinity of the PVPM to EDCs. This study introduces a new pathway for designing low‐cost and high‐performance membrane adsorbents for prompt and efficient capture of trace EDCs from water.

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History of Cyclodextrins

Cited by 17 publications

References 398 publications

130 years of cyclodextrin discovery for health, food, agriculture, and the industry: a review

130 years of cyclodextrin discovery for health, food, agriculture, and the industry: a review

Cyclodextrin Multicomponent Complexes: Pharmaceutical Applications

Co‐Aggregation Induced by Amphiphilic Membrane Interface for the Capture of Trace Endocrine Disruptors from Water

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