Histopatologi Limpa dan Limfonodus pada Kasus Lapangan dengan Dugaan Kematian Akibat Virus African Swine Fever Pada Babi di Kabupaten Kupang

Abstract

African swine fever is a fatal hemorrhagic disease in the Suidae family that has become a significant economic challenge to the global pig farming industry. The continued spread of this disease has threatened global pork production and food security. Recognizing the disease manifestations and pathological changes of ASF is critical for a comprehensive and accurate early warning program. Knowledge of the key characteristics of this disease, such as its pathology anatomy, and histopathology, is also needed for early identification of ASF before establishing a tentative diagnosis. This article aims to discuss the pathologic changes and to update disease understanding in order to improve early detection of ASF in the field. A histopathological study of clinical samples collected during the February to April 2021 outbreak of ASF was performed to determine the characteristic lesions of ASF. Three dead ASFV-suspected pigs from a farm in Kupang regency were examined in this study. The main characteristics at the gross pathology inspection were hemorrhage and enlargement of the spleens and lymph nodes. The histopathologic findings confirmed spleen and lymph nodes hemorrhages, as well as congestion of spleen and follicle necrotic at the lymph nodes. Based on the clinical manifestation, pathological findings, and epidemiology observation, it is suspected that the pigs were infected with ASF. However, a molecular diagnostic test should be taken to confirm the definitive cause of the pig’s deaths.

Laporan Kasus: Studi Morfopatologi Demam Babi Afrika pada Babi di Bogor, Jawa Barat

“…Perubahan tersebut tidak ditemukan pada babi kedua. Sebagai informasi, organ target utama pada ASF adalah sistem limfatik, limpa serta limfonodus yang mengalami radang disertai pendarahan (Gelolodo et al, 2021). Hasil pemeriksaan PA paru-paru menunjukkan warna yang tidak homogen dan kejadian pneumonia interstisial.…”

Sistem Pemeliharaan Babi dan Pemahaman Peternak Terhadap Demam Babi Afrika di Bangka Kenda,Manggarai, Nusa Tenggara Timur

“…Pada babi yang berhasil sembuh dari infeksi ASF, virus tetap bertahan di dalam jaringan dan darah, sehingga babi tersebut bertindak sebagai carrier (Sánchez-Cordón et al, 2018). Di dunia peternakan babi, penyakit ASF menjadi ancaman serius meskipun penyakit ini bersifat non-zoonotik (Gelolodo et al, 2021). Penyakit ASF ini dapat mengakibatkan kerugian ekonomi yang sangat signifikan akibat ketiadaan vaksin.…”

“…Penyakit ASF pertama kali dilaporkan di Kenya, Afrika pada tahun 1921 kemudian menyebar dan menjadi endemik di wilayah sub-Sahara Afrika termasuk di Pulau Madagaskar (Gelolodo et al, 2021) hingga saat ini menjadi endemik di Afrika (Sendow et al, 2020). Kejadian ASF di Benua Asia pertama kali terjadi di Tiongkok pada bulan Agustus 2018 (Zhao et al, 2019).…”