Histopathological study of a natural outbreak of Peste des petits ruminants in goats of Tamilnadu

Aruni, Wilson; Lalitha, Pattabhiraman; Mohan, Anand; Chitravelu, P.; Anbumani, S.

doi:10.1016/s0921-4488(97)00095-3

Cited by 30 publications

(23 citation statements)

References 8 publications

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“…Common clinical signs of infection with PPRV such as high fever, anorexia, necrotic stomatitis, dehydration, ulceration of mucous membranes and inflammation of the gastrointestinal tract leading to severe diarrhea, purulent ocular and nasal discharges, lacrimation and respiratory distress were observed in the present study which were also reported elsevere [38][39][40][41][42] .…”

Section: Discussionsupporting

confidence: 82%

Peste Des Petits Ruminants (PPR) Virus Infections in Goats in the Eastern Anatolia of Turkey

Gürçay¹,

Kizil²,

Baydar³

2013

Kafkas Univ Vet Fak Derg

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SummaryIn this study, a totally 98 materials were used consist of different samples such as blood, oro-nasal swap, lung, spleen and lymph node from goats (n=38) in the 28 flocks suspected the PPRV infection as clinically and macroscopic pathologic remarks. The goats that used in this study housed in the 11 different provinces of Eastern Anatolia. RT-PCR was used for the diagnosis of PPRV infection. PPRV nucleic acid was detected in 50 of 98 materials by RT-PCR. According to the results of RT-PCR, the PPRV nucleic acid was detected in 39.2% (11/28), 44.7% (17/38) and 45.4% (5/11) of the flocks, sampled animals and provinces in eastern anatolia, respectively. Diagnostic value of necropsy materials such as lymph node, spleen, lung and of clinical samples such as oro-nasal swap and blood were determined more valuable diagnostic materials in the diagnosis of PPRV infection by RT-PCR. Data showed that PPRV infections of the goats were widespread in the Eastern Anatolia region. Additionally, it is determined that RT-PCR is sensitive and reliable method in the diagnosis of PPRV infections. Keywords: Goat, PPR, RT-PCR Türkiye'nin Doğu Anadolu Bölgesin'deki Keçilerde Peste Des Petits Ruminants (PPR) Virus Enfeksiyonları ÖzetBu çalışmada, klinik ve makroskobik patolojik olarak PPRV enfeksiyonundan şüphelenilen 28 farklı sürüdeki keçilerden (n=38) alınan kan, oral-nazal swap, akciğer, dalak ve lenf nodülü gibi farklı örneklerden toplam 98 materyal kullanıldı. Bu çalışmada kullanılan keçiler Doğu Anadolu Bölgesi'nin 11 farklı ilinde yetiştiriliyordu. PPRV enfeksiyonunun teşhisinde RT-PCR kullanıldı. RT-PCR tekniğiyle 98 materyalin 50'sinde PPRV nükleik asidi belirlendi. RT-PCR sonuçlarına göre, PPRV nükleik asidi sürülerin %39.2'si (11/28), örneklenen hayvanların %44.7'si (17/38) ve Doğu Anadolu Bölgesinde örnekleme yapılan illerin %45.4 (5/11)' inde tespit edildi. RT-PCR ile PPRV enfeksiyonunun teşhisinde oral-nazal swap ve kan gibi klinik örnekler ve lenf nodülü, dalak ve akciğer gibi nekropsi materyali teşhis değeri yüksek materyal olarak belirlendi. Bu bilgiler keçilerin PPRV enfeksiyonunun Doğu Anadolu'da yaygın olduğunu ve PPRV enfeksiyonunun teşhisinde RT-PCR'ın duyarlı ve güvenilir bir metod olduğunu gösterdi.

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Section: Discussionsupporting

confidence: 82%

Peste Des Petits Ruminants (PPR) Virus Infections in Goats in the Eastern Anatolia of Turkey

Gürçay¹,

Kizil²,

Baydar³

2013

Kafkas Univ Vet Fak Derg

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“…The involvement of respiratory system in PPR is remarkable and pneumonia is a predominant sign in PPR. Most reports found lung involvement in almost more than 90 % of cases dying during outbreak of PPR [4,74,100,153,154]. Bronchopneumonia is a constant lesion, with possibility of pleuritis and hydrothorax.…”

Section: Diagnosismentioning

confidence: 99%

Diagnosis and control of peste des petits ruminants: a comprehensive review

Balamurugan¹,

Hemadri²,

Gajendragad³

et al. 2013

VirusDis.

130

118

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Peste des petits ruminants (PPR) is an acute, highly contagious, world organization for animal health (OIE) notifiable and economically important transboundary viral disease of sheep and goats associated with high morbidity and mortality and caused by PPR virus. PPR is considered as one of the main constraints in augmenting the productivity of small ruminants in developing countries and particularly severely affects poor farmer's economy. The disease is clinically manifested by pyrexia, oculo-nasal discharges, necrotizing and erosive stomatitis, gastroenteritis, diarrhoea and bronchopneumonia. The disease can be diagnosed from its clinical signs, pathological lesions, and specific detection of virus antigen/antibodies/genome in the clinical samples by various serological tests and molecular assays. PPR is the one of the priority animal diseases whose control is considered important for poverty alleviation in enzootic countries. Availability of effective and safe live attenuated cell culture PPR vaccines and diagnostics have boosted the recently launched centrally sponsored control programme in India and also in other countries. This review article primarily focus on the current scenario of PPR diagnosis and its control programme with advancement of research areas that have taken place in the recent years with future perspectives.

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“…Between December 2004 and September 2005, 9 dead animals (case Nos. 4,5,8,9,12,[18][19][20][21] and 8 organ samples (case Nos. 7, 10, 11, 13-17) from 14 different flocks (Flocks B2N) suspected to have PPR were submitted to the Kirikkale University Veterinary Faculty Pathology Laboratory for necropsy and histopathologic examination.…”

Section: Animalsmentioning

confidence: 99%

“…In addition, endothelial cells of cortical vessels (case Nos. 4,6) and numerous perivascular macrophages (case No. 4) showed immunoreactivity.…”

Section: Immunoperoxidase Findingsmentioning

confidence: 99%

Natural Peste des Petits Ruminants Virus Infection: Novel Pathologic Findings Resembling Other Morbillivirus Infections

et al. 2007

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Abstract. The present study describes pathologic and virologic findings in 15 sheep and 6 goats that died of natural peste des petits ruminants virus infection in Turkey. Pathologic findings included erosiveulcerative stomatitis, fibrino-necrotic tracheitis, bronchointerstitial pneumonia, multifocal coagulation necroses in the liver, and severe lymphocytolysis in lymphoid tissues. Syncytial cells were conspicuous, especially in the oral mucosa, pulmonary alveoli, liver, and lymphoid tissues. In addition to the typical tissue distribution, eosinophilic intracytoplasmic and/or intranuclear inclusions were observed in epithelial cells lining the renal pelvis and abomasal mucosa. Immunolabeling of the viral antigen was observed in the kidney, brain, rumen, abomasum, heart, and myocytes of the tongue besides its more typical locations. In this study, we report and describe in detail the first peste des petits ruminants endemic in Kirikkale Province, Central Anatolia of Turkey. In conclusion, these previously unreported pathologic findings in natural peste des petits ruminants virus infection establish a basis for resemblance to other morbillivirus infections, such as canine distemper and distemper of sea mammals. Reverse transcriptase-polymerase chain reaction analyses indicated that the 448-bp genome fragment was amplified in 18 cases (18/21, 85.7 %). Phylogenetic analysis showed that viruses belong to lineage 4 in the peste des petits ruminants virus common phylogenetic tree.

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Histopathological study of a natural outbreak of Peste des petits ruminants in goats of Tamilnadu

Cited by 30 publications

References 8 publications

Peste Des Petits Ruminants (PPR) Virus Infections in Goats in the Eastern Anatolia of Turkey

Peste Des Petits Ruminants (PPR) Virus Infections in Goats in the Eastern Anatolia of Turkey

Diagnosis and control of peste des petits ruminants: a comprehensive review

Natural Peste des Petits Ruminants Virus Infection: Novel Pathologic Findings Resembling Other Morbillivirus Infections

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