Histopathological Spectrum of Hyperpigmented Lesions of Skin

Jayker, Shushan Shweta; Anantharaj, Jyothi; Surhonne, Sharmila P; Ramachandra, Ramya; Gurumurthy, Radhika Yajaman

doi:10.14260/jemds/2016/453

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…No case of Lichen amyloidosis was observed. 16 Saha R et al in their study showed similar findings where Lichen planus and its variants constituting 20 cases out of 52 cases. This was followed by 14 cases of Post inflammatory hyperpigmentation, 5 cases of Macular amyloidosis, 4 cases of Lichen simplex chronicus, 3 cases of Morphea, 2 cases each of Lichen amyloidosis and Prurigo nodularis and 1 case each of DLE and Dawling Degos.…”

Section: Discussionmentioning

confidence: 55%

Histopathological spectrum of hyperpigmented skin lesions- A study in a tertiary hospital from western Uttar Pradesh

Jaiswal¹,

Avani²,

Gupta³

et al. 2023

PJMS

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Hyperpigmented skin lesions are the cause of concern for general people and are commonest reason for dermatology consultation. An accurate histopathological diagnosis helps a dermatologist in appropriate management of such lesionsA retroprospective study of 100 cases of skin biopsies in hyperpigmented lesions was conducted from January 2020 to July 2021 at our institute. Inadequate skin biopsies, lesions of neoplastic or congenital etiology were excluded from the study. A clinico-histopathological correlation was also done.Out of 100 skin biopsies studied, most cases (50%) were in the age group of 21-40 years. Females were more affected than males; F:M ::1.27:1 and the most common histopathological diagnosis was Lichen planus and its variants (38%).Hyperpigmented skin lesions can be the only presentation of wide variety of the skin lesions. To make the diagnosis;proper and detailed history, clinical examination and microscopic examination of the biopsies is must which helps the doctor to treat the patients effectively.

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Section: Discussionmentioning

confidence: 55%

Histopathological spectrum of hyperpigmented skin lesions- A study in a tertiary hospital from western Uttar Pradesh

Jaiswal¹,

Avani²,

Gupta³

et al. 2023

PJMS

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A histo-pathological study with an emphasis on stratification of pigmented lesions of the skin

Anand¹,

Ilanthodi²,

N³

et al. 2020

IJPO

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Pigmented lesions can be close mimickers of melanoma and clinically challenging to diagnose. These can be melanocytic or non-melanocytic pigmented disorders. Pigmented lesions are close mimickers of melanoma and histopathology is a cornerstone for diagnosing these lesions. 1.To study the histomorphological patterns of pigmented lesions of the skin; 2. To categorise and differentiate pigmented lesions from melanoma based on histomorphology.A total of 70 histologically diagnosed cases of pigmented lesions of the skin were retrospectively studied from January 2018 to December 2019 in department of Pathology, of a Tertiary care center, Mangalore (India). Clinically suspicious skin lesions were taken up for the study. Sections from the skin punch biopsies and wide excision of the lesion were processed, stained with Hematoxylin and Eosin stain and studied for its histomorphological features.Out of the 70 cases studied, 22 cases were melanocytic lesions including 12 cases of Malignant melanoma (17.1%), Benign Naevi- 10 cases (14.2%) and 48 cases were non-melanocytic lesions including Lichen planus- 30 cases (42%), Seborrheic keratosis- 10 cases (14.3%), Basal cell carcinoma- 8 cases (11.4%).The pigmented lesions are categorised into melanocytic and non melanocytic lesions for a better understanding. Among the Melanocytic lesions, our study witnessed predominantly cutaneous melanoma. And in non melanocytic lesions lichen planus predominated.

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Clinico-Pathological Study of Pigmented Skin Lesions

Jagannadham¹,

Chappa²,

Mohammad³

et al. 2020

jebmh

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BACKGROUND Pigmentary problems are one of the most frequent causes for dermatologic consultation. Skin colour is highly individual and the variations are controlled by numerous genes. Correct diagnosis of skin disorders including pigmented lesions depends on histopathologic examination of skin biopsies and clinicopathologic correlation. METHODS This is a hospital based observational study done for a period of 2 years from July 2017 to June 2019 with a sample size of 88 cases in the Department of Pathology, Andhra Medical College, Visakhapatnam. Specimens were formalin fixed and the tissue was adequately processed for histopathological examination. The sections were stained routinely with haematoxylin and eosin and examined under light microscopy. RESULTS Out of the 88 cases, 30 cases were inflammatory lesions which include 14 cases of classic lichen planus, 6 cases of lichen planus hypertrophicus, 9 cases of lichen planus pigmentosus and 1 case of lichenoid keratosis. 35 cases were benign lesions comprising 21 cases of benign melanocytic nevi and 14 cases of seborrheic keratosis. 23 malignant lesions include 16 cases of basal cell carcinoma and 7 cases of melanoma. Most common affected age group was 51-60 yrs. Most common site involved in malignant lesions was face (34.33%). There is slight female preponderance. Most common pigmented lesion under malignant category was basal cell carcinoma about 16 cases. 75 cases (85%) were correlated clinically. CONCLUSIONS Classic Lichen planus is the most common lesion seen under inflammatory category. The diagnosis of seborrheic keratosis is mainly based on the histopathological examination in order to differentiate from other pigmented skin lesions, hence a careful histopathological diagnosis is important.

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Histopathological Spectrum of Hyperpigmented Lesions of Skin

Abstract: BACKGROUNDHyperpigmentation of skin is one of the commonest cosmetic skin complaint encountered in Dermatology Outpatient Clinic. Evidence for a correct diagnosis may be lacking without histopathologic examination of skin biopsies.

Cited by 3 publications

References 8 publications

Histopathological spectrum of hyperpigmented skin lesions- A study in a tertiary hospital from western Uttar Pradesh

Histopathological spectrum of hyperpigmented skin lesions- A study in a tertiary hospital from western Uttar Pradesh

A histo-pathological study with an emphasis on stratification of pigmented lesions of the skin

Clinico-Pathological Study of Pigmented Skin Lesions

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