Histopathological Findings in Uterus and Cervix of Hysterectomy Specimens

Abstract

<strong>Background:</strong> For centuries, the female reproductive system has been affected by various abnormalities and diseases and hence has been the subject of interest and the basis for the gynaecological practice. The uterus being a vital reproductive and hormone-responsive organ, is subjected to a variety of physiological changes and benign and malignant disorders. <strong>Aims and Objectives:</strong> To study the indications of hysterectomy, to study gross and histopathological features of uterus and cervix in hysterectomy specimens and correlate with clinical findings. <strong>Material and Methods:</strong> This was a descriptive study of the gross and histopathological findings of uterus and cervix in 150 hysterectomy specimens received in the department. The hysterectomy specimens received were fixed in 10% formalin for 24 hours, were examined grossly and necessary sections were obtained. The tissue pieces were then processed in automated tissue processor, well labelled paraffin blocks were made. Approximately 2-3μ thickness sections were cut with the help of microtome and were stained routinely by Hematoxylin & Eosin stain and special stains like PAS or other were used wherever necessary. The histopathological findings of uterus and cervix were noted and these findings were then correlated with clinical diagnosis. <strong>Results:</strong> Overall clinicopathological correlation was noted in all 150 cases. In cases of uterine fibroid it was 69.7% and 100% in case of endometrial carcinoma and cervical dysplasia. Most common pathology found was uterine leiomyomas in 48 cases and next to it was adenomyosis in 30 cases. <strong>Conclusion:</strong> It can be concluded that clinico-pathological correlation in case of endometrial cancer and uterine fibroid is excellent, but in case of DUB and prolapse uterus it varies. This signifies the importance of clinico-pathological correlation in all cases of hysterectomy to improve the clinical outcome and post-operative management.

An audit of hysterectomies: indications, complications and clinico pathological analysis of hysterectomy specimens in a tertiary care center

“…Most common age group was 41-50 years. Similar age group was observed in other studies conducted by Saravana A et al, Perveen S et al, Medhi P et al, Domblae V et al, Patil H et al, Sharma C et al [2][3][4][5][6][7] Most of the cases were parous women, majority were with para 2. This was similar to studies conducted by Saravana A et al 2 Most common route of hysterectomy was abdominal route.…”

Histopathological analysis of hysterectomy specimens in a tertiary care centre: study of 160 cases

“…The most common route of hysterectomy was total abdominal hysterectomy with bilateral salpingoophrectomy (102; 63.7%) followed by total abdominal hysterectomy (38; 23.7%). Similar observations were made by Ajmera et al and Patil et al 3,7 The most common age group was 41-50 years in the present study which was in concordance with Domblae et al, Patil et al and many others. 3,8 In this study the most common In our study most common finding in endometrium was proliferative phase, myometrium was leiomyoma and cervix was chronic cervitis which was comparable with other studies conducted by Patil et al and Khunte et al 3,12 Verma et al had similar findings in endometrium and cervix but in myometrium adenomyosis was most common in his study.…”

“…The lesions of the uterine corpus and cervix account for most patient visits to gynaecologists. 3 Many treatment are available nowadays including medical and conservative surgical procedures but hysterectomy remains the most preferred method to manage gynaecological disorders. 4 Hysterectomy is the removal of the uterus and it is the most common gynecological procedure performed in the females worldwide, as it is affected by various nonneoplastic and neoplastic conditions during the life time of a woman.…”

Histopathological analysis of hysterectomy specimens: one year study

“…In an analysis of 150 cases by Harshal A. et al 3 Atrophic endometrium was seen in 20 cases, all except one was diagnosed in vaginal hysterectomy done in the postmenopausal women. Endometrial polyp was seen in 5 cases.…”

“…However, other studies have shown a larger percentage of patients presenting with dual pathology. 3 Chronic cervicitis is the most common finding in the cervix histopathologically. In our study 29% of the cases were chronic cervicitis.…”