Histopathological Features of Dental Pulp Tissue from Bleached Mandibular Incisors

Roderjan, Douglas Augusto; Stanislawczuk, Rodrigo; Hebling, Josimeri; Costa, Carlos Alberto de Souza; Soares, Diana Gabriela; Reis, Alessandra; Loguércio, Alessandro Dourado

doi:10.17265/2161-6221/2014.06.006

Cited by 4 publications

(2 citation statements)

References 29 publications

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“…[ 11 ] and Roderjan et al . [ 10 13 ], does not agree with previous literature findings. Earlier in vivo studies demonstrated insignificant pulp damage after in-office bleaching.…”

Section: Discussioncontrasting

confidence: 63%

“…Within 15 minutes of the application of bleaching gel, hydrogen peroxide can be found in the pulp tissue [ 9 ]. This molecule is capable of causing negative effects on the pulp, such as an inflammatory reaction and even partial tissue necrosis [ 10 11 12 13 ]. Several in vitro studies have shown damage to pulp cells stemming from the trans-enamel and trans-dentin diffusion of high concentrations of hydrogen peroxide [ 14 15 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of medium or high concentrations of in-office dental bleaching gel on the human pulp response in the mandibular incisors

Roderjan

Stanislawczuk²,

Soares

et al. 2023

Restor Dent Endod

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Objectives The present study evaluated the pulp response of human mandibular incisors subjected to in-office dental bleaching using gels with medium or high concentrations of hydrogen peroxide (HP). Materials and Methods The following groups were compared: 35% HP (HP35; n = 5) or 20% HP (HP20; n = 4). In the control group (CONT; n = 2), no dental bleaching was performed. The color change (CC) was registered at baseline and after 2 days using the Vita Classical shade guide. Tooth sensitivity (TS) was also recorded for 2 days post-bleaching. The teeth were extracted 2 days after the clinical procedure and subjected to histological analysis. The CC and overall scores for histological evaluation were evaluated by the Kruskal-Wallis and Mann-Whitney tests. The percentage of patients with TS was evaluated by the Fisher exact test (α = 0.05). Results The CC and TS of the HP35 group were significantly higher than those of the CONT group ( p < 0.05) and the HP20 group showed an intermediate response, without significant differences from either the HP35 or CONT group ( p > 0.05). In both experimental groups, the coronal pulp tissue exhibited partial necrosis associated with tertiary dentin deposition. Overall, the subjacent pulp tissue exhibited a mild inflammatory response. Conclusions In-office bleaching therapies using bleaching gels with 20% or 35% HP caused similar pulp damage to the mandibular incisors, characterized by partial necrosis, tertiary dentin deposition, and mild inflammation.

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“…[ 11 ] and Roderjan et al . [ 10 13 ], does not agree with previous literature findings. Earlier in vivo studies demonstrated insignificant pulp damage after in-office bleaching.…”

Section: Discussioncontrasting

confidence: 63%