Histologic pattern analysis of basal cell carcinoma

Mohs' micrographic surgery for basal cell carcinomas on the eyelids and medial canthal areaI

“…Many ways of classifying BCCs have been suggested (Lowe & Rapini 1991;Sexton et al 1990;Strutton 1997). We subtyped the tumours in morpheiform, intermediate, nodular/micronodular and superficial BCCs, reflecting the aggressiveness of the tumour growth.…”

Value of p53 protein in biological behavior of basal cell carcinoma and in normal epithelia adjacent to carcinomas

“…4,13 BSCC -Dermal infiltration of nests of basaloid cells, with peripheral palisading demonstrating foci of squamous cells with intercellular bridges and epithelial pearls. Both pseudoepithelial hyperplasia associated with BCC and the keratinizing form of BCC were excluded.…”

Basal cell carcinoma: biology, morphology and clinical implications

“…7 In one large retrospective series of 1039 consecutive neoplasms, and using a slightly dissimilar classification scheme, 21% were nodular, 17.4% were superficial, 14.5% were micronodular, 7.4% were infiltrative and 1.1% were morpheiform. 32 Roughly one-third of all tumors showed an admixture of patterns. 32 Superficial BCC Superficial BCC is characterized by a proliferation of atypical basaloid cells that form an axis parallel to the epidermal surface and demonstrate slit-like retraction of the palisaded basal cells from the subjacent stroma (Figure 4).…”

“…32 Roughly one-third of all tumors showed an admixture of patterns. 32 Superficial BCC Superficial BCC is characterized by a proliferation of atypical basaloid cells that form an axis parallel to the epidermal surface and demonstrate slit-like retraction of the palisaded basal cells from the subjacent stroma (Figure 4). 7 The resulting cleft-like spaces often contain alcian blue-positive mesenchymal mucoid material, a presumed product of the stromal cells.…”