Highly Sensitive Electrochemical Sensor Based on PEDOT:PSS-β-CD-SWCNT-COOH Modified Glassy Carbon Electrode Enables Trace Analysis Shikonin

Abstract

An electrochemical sensor based on PEDOT:PSS-β-CD-SWCNT-COOH/GCE for highly sensitive analysis of shikonin (SHI) in PBS buffer solution was reported. PEDOT:PSS-β-CD-SWCNT-COOH composite was obtained by using poly(3,4ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS), β-Cyclodextrin (β-CD) and carboxylated single-walled carbon nanotube (SWCNT-COOH) to modify glassy carbon electrode (GCE) and characterized by scanning electron microscopy and electrochemical impedance spectroscopies. In optimized conditions, PEDOT:PSS-β-CD-SWCNT-COOH had a high sensitivity to SHI and it could detect SHI in linear ranges 6 nM to 30 μM with a low detection limit of 1.8 nM. And a series of experiments showed that the modified electrode exhibited good repeatability, reproducibility, and selectivity to electrochemical determination of SHI.

Multifunctional Porous Nanohybrid Based on Graphene-Like Tungsten Disulfide on Poly(3,4-ethoxylenedioxythiophene) for Supercapacitor and Electrochemical Nanosensing of Quercetin

“…The peak current reduced when the electrodeposited time was less than 15 s, which might be assigned to the too thin film. 43 However, the peak current also reduced when the electrodeposited time is more than 15 s, which might be because the polymeric film was too thick, 43 Thus, 15 s was selected as the electrodeposited time for the electrochemical polymerization of EDOT in acetonitrile solution. The mechanism for preparation of WS 2 /PEDOT was that the electrochemical synthesis of PEDOT was a cationic radical polymerization, and the anion such as the perchlorate was used as the dopant to balance the charge, other material like WS 2 was incorporated into polymeric films to improve morphologies and properties.…”

“…The calculation of A was also similar with our previous work. 43 According to the Randles-Sevick equation as follows:…”

“…[38][39][40][41][42] TMDs were known to be electrochemically active materials for applications in SCs and sensors, but to date, very few WS 2 was used to fabricate SCs and sensors relative to molybdenum disulfide due to the poor electronic conductivity. 43,44 Herein, a multifunctional porous nanohybrid based on 2D layered WS 2 nanosheet onto a porous and conductive PEDOT was successfully developed for supercapacitor and nanosensor for voltammetric detection of Chinese traditional herbal drug Qu in a lotus leaves extract sample compared with HPLC. Instrumentation.-The electrochemical behaviors were performed by CHI660E electrochemical workstation (Shanghai Chenhua Instrument Co., Ltd., China), carrying through a onechamber three-electrode system under computer control.…”

Graphene-Based Sensor for the Detection of Cortisol for Stress Level Monitoring and Diagnostics

“…Electrochemical sensors are attractive devices with potential applications in quality control of food, water and pharmaceutical compounds [ 1 , 2 , 3 ]. In recent years, there has taken place an ongoing search in the scientific community for low-cost and high-precision electrochemical sensors [ 4 , 5 , 6 ].…”

The Fabrication of Multiple Stimuli-Responsive Film Electrode and Logic Gates of Rutin

“…Various electrochemical sensors have aroused great interests among researchers, such as glucose sensors, [1][2][3] sensors modified with nanomaterials, [4][5][6][7] and other types of sensors. [8][9][10] Hydrogel polymer is assembled on electrode surface to form thin films, which are called as environmental-sensitive hydrogel film sensors.…”