Highly Sensitive Determination of 2,4,6-Trichlorophenol by Using a Novel SiO₂@MIPIL Fluorescence Sensor with a Double Recognition Functional Monomer

Abstract

A novel SiO2@ MIPIL fluorescence sensor for the highly sensitive detection of 2,4,6-trichlorophenol was prepared by using surface molecularly imprinting technology with SiO2 microspheres as carriers and 3,3′-(anthracene-9,10-diylbis­(methylene))­bis­(1-vinyl-1H-imidazole-3-ium) chloride as a double recognition fluorescence functional monomer. The prepared molecularly imprinted polymer (SiO2@MIPIL) was characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, laser confocal microscopy, and nuclear magnetic resonance. Compared with the polymer obtained via bulk polymerization (MIPIL), the surface molecularly imprinted polymer (SiO2@MIPIL) has a better linear range (0.1–50 nM), lower detection limit (89 pM), and shorter detection time (approximately 1.5 min). The fluorescence sensor also shows good specificity, high sensitivity, good stability, and reusability. Satisfactory results were obtained when using this sensor in industrial wastewater and spiked environmental water.

A gel fluorescence sensor based on CDs@SiO2/FeS2@MIPs for the visual detection of p-chlorophenol

“…The extra absorption peak at 1650 cm À1 for CDs@SiO 2 /FeS 2 @MIPs compared to CDs@SiO 2 /FeS 2 @NIPs is a blue shi phenomenon caused by the hydrogen bond that formed between the -COOH bond on the functional monomer and the phenolic hydroxyl group on the template molecule. 45 The zeta potential value of CDs@SiO 2 / FeS 2 @MIPs was À52.1 mV. As p-chlorophenol was in the anionic form in a weakly acidic environment and had a negative zeta potential value, the sensing of p-chlorophenol was likely generated by the hydrogen bond rather than the electrostatic…”

Selective Preparation of Mo2N and MoN with High Surface Area for Flexible SERS Sensing

“…Trichlorophenol (2,4,5-TCP) and dichlorophenol (2,4-DCP) are two typical environmental pollutants. 28 Benefitting from the high adsorption effect and electromagnetic field hot spot (HS) effect produced by SCP nanostructure, SERS test results show that trace detection of 2,4,5-TCP and 2,4-DCP is achieved on the γ-Mo 2 N flexible membrane (Figure 5E,F), and the detection limit is up to 10 −11 M. By evaluating the enhancement effect of the substrate on the Raman signal of the Rhodamine 6G molecules (R6G, a probe most commonly used to calculate Raman enhancement factor), the enhancement factor obtained is 5.2 × 10 7 . As far as we know, this may be the first discovery of the SERS effect of γ-Mo 2 N, which can be attributed to its strong SPR effect and the hot spot effect caused by the SCP nanostructure.…”

“…The strong SPR effect and the interconnected SCP structure make the novel γ-Mo 2 N nanobelts possess excellent SERS effects (Figure D). Trichlorophenol (2,4,5-TCP) and dichlorophenol (2,4-DCP) are two typical environmental pollutants . Benefitting from the high adsorption effect and electromagnetic field hot spot (HS) effect produced by SCP nanostructure, SERS test results show that trace detection of 2,4,5-TCP and 2,4-DCP is achieved on the γ-Mo 2 N flexible membrane (Figure E,F), and the detection limit is up to 10 –11 M. By evaluating the enhancement effect of the substrate on the Raman signal of the Rhodamine 6G molecules (R6G, a probe most commonly used to calculate Raman enhancement factor), the enhancement factor obtained is 5.2 × 10 7 .…”

Gold Nano/Micro-Islands Overcome the Molecularly Imprinted Polymer Limitations to Achieve Ultrasensitive Protein Detection

“…10−12 Surface imprinting techniques and nanomaterial-conjugated MIPs can be successfully used to improve the sensitivity and simplify the fabrication process. 13,14 Specifically for proteins, template removal is the most challenging step in fabrication because it is usually performed at high temperatures and for several minutes using alkaline or acidic solutions. 2,15,16 Surface imprinting technology is one of the most promising methods for the fabrication of MIPs, via two common strategies.…”

“…Molecularly imprinted polymers (MIPs), a group of biomimetic receptors, have gained significant attention as an alternative to antibody-based immunosensors owing to high stability at room temperature and a cost-effective fabrication process. − However, current challenges and limitations on the application of MIPs in biosensing are mainly focused on improving their selectivity, sensitivity, and ease of fabrication. In terms of selectivity, the combination of aptamers and MIPs is a promising approach. − Surface imprinting techniques and nanomaterial-conjugated MIPs can be successfully used to improve the sensitivity and simplify the fabrication process. , Specifically for proteins, template removal is the most challenging step in fabrication because it is usually performed at high temperatures and for several minutes using alkaline or acidic solutions. ,, Surface imprinting technology is one of the most promising methods for the fabrication of MIPs, via two common strategies. , First, by combining the template and monomer and subsequent polymerization, and second, by immobilizing protein on the surface and carrying out UV polymerization or electropolymerization. − The former can undesirably cause confinement of the protein in the polymeric layer, while in the latter, controlling thickness of the polymeric layer is crucial. , Thus, the fabrication of ultrathin and controllable polymeric layers with high sensitivity is known as another current challenge in the field of MIPs. Among various surface imprinting methods, electropolymerization provides a compact and ultrathin polymeric layer on the surface of the biosensor to enhance the read-out signal and sensitivity for detection of proteins, , peptides, small molecules, bacteria, and metallic ions …”