A systematic review and meta-analysis was conducted in an attempt to systematically collect and evaluate the associations of epidemiological, comorbidity factors with the severity and prognosis of coronavirus disease 2019 (COVID-19). The systematic review and meta-analysis was conducted according to the guidelines proposed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Sixty nine publications met our study criteria, and 61 studies with more than 10,000 COVID-19 cases were eligible for the quantitative synthesis. We found that the males had significantly higher disease severity (RR: 1.20, 95% CI: 1.13-1.27, P <0.001) and more prognostic endpoints. Older age was found to be significantly associated with the disease severity and six prognostic endpoints. Chronic kidney disease contributed mostly for death (RR: 7.10, 95% CI: 3.14-16.02), chronic obstructive pulmonary disease (COPD) for disease severity (RR: 4.20, 95% CI: 2.82-6.25), admission to intensive care unit (ICU) (RR: 5.61, 95% CI: 2.68-11.76), the composite endpoint (RR: 8.52, 95% CI: 4.36-16.65,), invasive ventilation (RR: 6.53, 95% CI: 2.70-15.84), and disease progression (RR: 7.48, 95% CI: 1.60-35.05), cerebrovascular disease for acute respiratory distress syndrome (ARDS) (RR: 3.15, 95% CI: 1.23-8.04), coronary heart disease for cardiac abnormality (RR: 5.37, 95% CI: 1.74-16.54). Our study highlighted that the male gender, older age and comorbidities owned strong epidemiological evidence of associations with the severity and prognosis of COVID-19.
Materials with ultralong phosphorescence have wide-ranging application prospects in biological imaging, light-emitting devices, and anti-counterfeiting. Usually, molecular phosphorescence is significantly quenched with increasing temperature, rendering it difficult to achieve high-efficiency and ultralong room temperature phosphorescence. Herein, we spearhead this challenging effort to design thermal-quenching resistant phosphorescent materials based on an effective intermediate energy buffer and energy transfer route. Co-crystallized assembly of zero-dimensional metal halide organic-inorganic hybrids enables ultralong room temperature phosphorescence of (Ph4P)2Cd2Br6 that maintains luminescent stability across a wide temperature range from 100 to 320 K (ΔT = 220 °C) with the room temperature phosphorescence quantum yield of 62.79% and lifetime of 37.85 ms, which exceeds those of other state-of-the-art systems. Therefore, this work not only describes a design for thermal-quenching-resistant luminescent materials with high efficiency, but also demonstrates an effective way to obtain intelligent systems with long-lasting room temperature phosphorescence for optical storage and logic compilation applications.
Efficient
nitrogen fixation under ambient conditions is an exigent
task in both basic research and industrial applications. Recently,
reduction of N2 to NH3 based on photocatalysis
and/or electrocatalysis offers a possible route to the typical Haber–Bosch
process. However, achieving a high yield of N2 reduction
reaction (NRR) is still a challenging goal because of the limitations
of efficient catalysts. Herein, we propose a photoelectrochemical
NRR route based on the rational design of MoS2@TiO2 semiconductor nanojunction catalysts through a facile hydrothermal
synthetic method. The developed MoS2@TiO2 photocathode
attains a high NH3 yield rate (1.42 × 10–6 mol h–1 cm–2) and a superhigh
faradaic efficiency (65.52%), which is the highest record to the best
of our knowledge. Moreover, MoS2@TiO2 exhibits
high stability over 10 consecutive reaction cycles. Therefore, this
work demonstrates an effective NRR photoelectrocatalyst and results
in a breakthrough in the low faradaic efficiency because of the interfacial
electronic coupling and synergistic effects between the MoS2 and TiO2 components.
Perovskite/silicon tandem solar cells are promising avenues for achieving high‐performance photovoltaics with low costs. However, the highest certified efficiency of perovskite/silicon tandem devices based on economically matured silicon heterojunction technology (SHJ) with fully textured wafer is only 25.2% due to incompatibility between the limitation of fabrication technology which is not compatible with the production‐line silicon wafer. Here, a molecular‐level nanotechnology is developed by designing NiOx/2PACz ([2‐(9H‐carbazol‐9‐yl) ethyl]phosphonic acid) as an ultrathin hybrid hole transport layer (HTL) above indium tin oxide (ITO) recombination junction, to serve as a vital pivot for achieving a conformal deposition of high‐quality perovskite layer on top. The NiOx interlayer facilitates a uniform self‐assembly of 2PACz molecules onto the fully textured surface, thus avoiding direct contact between ITO and perovskite top‐cell for a minimal shunt loss. As a result of such interfacial engineering, the fully textured perovskite/silicon tandem cells obtain a certified efficiency of 28.84% on a 1.2‐cm2 masked area, which is the highest performance to date based on the fully textured, production‐line compatible SHJ. This work advances commercially promising photovoltaics with high performance and low costs by adopting a meticulously designed HTL/perovskite interface.
The development of bifunctional and stable non-noble metal electrocatalysts for the high-performance hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) is very important and challenging for renewable energy.
Smart molecular crystals with light‐driven mechanical responses have received interest owing to their potential uses in molecular machines, artificial muscles, and biomimetics. However, challenges remain in control over both the dynamic photo‐mechanical behaviors and static photonic properties of molecular crystals based on the same molecule. Herein, we show the construction of isostructural co‐crystals allows their light‐induced cracking and jumping behaviors (photosalient effect) to be controlled. Hydrogen‐bonded co‐crystals from 4‐(1‐naphthylvinyl)pyridine (NVP) with co‐formers (tetrafluoro‐4‐hydroxybenzoic acid (THA) and tetrafluorobenzoic acid (TA)) crystallize as isostructural crystals, but have different static and dynamic photo‐mechanical behaviors. These differences are due to alternations in the orientation of NVP and hydrogen‐bonding modes of the co‐formers. After light activation, the 1D NVP‐TA crystal splits and shears off within 1 s. For NVP‐THA, its photostability and high quantum yield give novel photonic properties, including low optical waveguide loss, highly polarized anisotropy, and efficient up‐conversion fluorescence.
Ammonia is the main precursor for the production of fertilizers, a hydrogen energy carrier and an emerging clean fuel that plays a crucial role in sustaining life on the globe.
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