Highly sensitive and efficient voltammetric determination of ascorbic acid in food and pharmaceutical samples from aqueous solutions based on nanostructure carbon paste electrode as a sensor

Pardakhty, Abbas; Ahmadzadeh, Saeid; Avazpour, Sanaz; Gupta, Vinod Kumar

doi:10.1016/j.molliq.2016.01.010

Cited by 48 publications

(17 citation statements)

References 49 publications

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“…According to the Nernstian equation, the results showed that the number of protons and electrons are equal in the redox oxidation mechanism of PAR, A and ASA. Therefore, we can propose that the electrochemical oxidations of PAR, A and ASA occur on hydroxyl moieties of all compounds due to deprotonations and the loss of electrons (See Scheme 1 in Supporting Information) .…”

Section: Resultsmentioning

confidence: 99%

Application of Single‐use Electrode Based on Nano‐clay and MWCNT for Simultaneous Determination of Acetaminophen, Ascorbic Acid and Acetylsalicylic Acid in Pharmaceutical Dosage

Bayraktepe

Yazan

2020

Electroanalysis

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In this study, a highly sensitive, selective and cost‐effective electrochemical nano‐sensor has been developed for the first time so as to facilitate the simultaneous and low‐level detection of acetaminophen (paracetamol, PAR), ascorbic acid (A) and acetylsalicylic acid (ASA) ternary mixture. The sensor is based on nano‐sepiolite clay (SEP) with multiwall carbon nanotubes (MWCNTs) onto electrochemically pretreated pencil graphite electrode (pPGE). The surface properties of the sensor were examined by using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM) techniques. The pH effect, composition of modifiers, immobilization time, deposition potential and deposition time values were optimized to reach the best response of PAR, A and ASA. Moreover, in optimum analytical conditions, adsorptive stripping differential pulse voltammmetric (AdsDPV) method was developed for the simultaneous analysis of the ternary mixtures concerned by using SEP/MWCNTs/pPGE sensor. This sensor exhibited the low detection limits of 0.018, 0.042 and 0.047 μM for PAR, A and ASA ternary mixture, respectively. The developed AdsDPV method was applied for quantitative determination of PAR, A and ASA in the pharmaceutical formulation. The recovery experiments were carried out to control the accuracy and precision of the method. The obtained voltammetric recoveries were comparable with the HPLC data given in the literature.

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Section: Resultsmentioning

confidence: 99%

Application of Single‐use Electrode Based on Nano‐clay and MWCNT for Simultaneous Determination of Acetaminophen, Ascorbic Acid and Acetylsalicylic Acid in Pharmaceutical Dosage

Bayraktepe

Yazan

2020

Electroanalysis

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“…At present, the main detection methods are chemical uorescence method, 17 uorescence, 18 electron spin capture, [19][20][21][22][23] chromatography, 24 and so on. [25][26][27][28] Some of these methods require expensive instruments, and some operations are very complicated.…”

Section: Analytic Methods and Calculationmentioning

confidence: 99%

Kinetic study of hydroxyl radical formation in a continuous hydroxyl generation system

Wang

Zhang

2018

RSC Adv.

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“…1,2 Additionally, AA is also associated with many chronic diseases, including gout, mucositis, infertility, skin disease, HIV/AIDS, and cancer. [2][3][4][5] However, AA is an exogenous substance and cannot be synthesized in the human body. Therefore, taking a daily supplement of AA via food diet is necessary for the human health.…”

Section: Introductionmentioning

confidence: 99%

Microwave-assisted Synthesis of N,S-co-carbon Dots as Switch-on Fluorescent Sensor for Rapid and Sensitive Detection of Ascorbic Acid in Processed Fruit Juice

et al. 2019

ANAL. SCI.

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To achieve a rapid, sensitive, and economical method for the detection of ascorbic acid (AA) in the presence of Fe 3+ , a nitrogen and sulfur co-doped carbon dots (N,S-co-CDs) based fluorescence sensing system was developed. In this work, N,S-co-CDs were successfully synthesized via a one-step microwave-assisted method within 2.5 min using ammonium citrate and L-cysteine as precursors. The fluorescence of N,S-co-CDs was quenched (off) by Fe 3+ through a static-quenching mechanism. Subsequently, the fluorescence was recovered (on) after introducing AA into the quenched system, which was attributed to the reduction effect of AA for Fe 3+. Therefore, a switch-on sensor (N,S-co-CDs/Fe 3+ system) was developed for AA detection. Under optimal conditions, the limit of detection (LOD) of 2.31 μmol/L for AA was obtained over a linear range from 0 to 150 μmol/L. Furthermore, the proposed sensing method was successfully applied to detect AA in processed fruit juice with satisfactory results. The most important is that the sensor derived from a microwave-assisted method has simple and eco-friendly synthesis processes, is rapid, and has high detection efficiency. Therefore, such a switch-on sensor may be a promising candidate sensor for AA detection in processed fruit samples.

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Highly sensitive and efficient voltammetric determination of ascorbic acid in food and pharmaceutical samples from aqueous solutions based on nanostructure carbon paste electrode as a sensor

Cited by 48 publications

References 49 publications

Application of Single‐use Electrode Based on Nano‐clay and MWCNT for Simultaneous Determination of Acetaminophen, Ascorbic Acid and Acetylsalicylic Acid in Pharmaceutical Dosage

Application of Single‐use Electrode Based on Nano‐clay and MWCNT for Simultaneous Determination of Acetaminophen, Ascorbic Acid and Acetylsalicylic Acid in Pharmaceutical Dosage

Kinetic study of hydroxyl radical formation in a continuous hydroxyl generation system

Microwave-assisted Synthesis of N,S-co-carbon Dots as Switch-on Fluorescent Sensor for Rapid and Sensitive Detection of Ascorbic Acid in Processed Fruit Juice

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